KEGG   ENZYME: 2.3.1.137
Entry
EC 2.3.1.137                Enzyme                                 
Name
carnitine O-octanoyltransferase;
medium-chain/long-chain carnitine acyltransferase;
carnitine medium-chain acyltransferase;
easily solubilized mitochondrial carnitine palmitoyltransferase;
overt mitochondrial carnitine palmitoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
octanoyl-CoA:L-carnitine O-octanoyltransferase
Reaction(IUBMB)
octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine [RN:R03779]
Reaction(KEGG)
R03779
Substrate
octanoyl-CoA [CPD:C01944];
L-carnitine [CPD:C00318]
Product
CoA [CPD:C00010];
L-octanoylcarnitine [CPD:C02838]
Comment
Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC 2.3.1.7 (carnitine O-acetyltransferase) and EC 2.3.1.21 (carnitine O-palmitoyltransferase).
History
EC 2.3.1.137 created 1992
Orthology
K05940  carnitine O-octanoyltransferase
Genes
HSA54677(CROT)
PTR463514(CROT)
PPS100977046(CROT)
GGO101140286(CROT)
PON100452848(CROT)
NLE100601416(CROT)
HMH116810866(CROT)
MCC706186(CROT)
MCF101925311(CROT)
MTHB126951273
MNI105475441(CROT)
CSAB103226610(CROT)
CATY105595519(CROT)
PANU101007882(CROT)
TGE112621434(CROT)
MLEU105550952(CROT)
RRO104668030(CROT)
RBB108515085(CROT)
TFN117072397(CROT)
PTEH111552444(CROT)
CANG105525960(CROT)
CJC100399460(CROT)
SBQ101051126(CROT)
CIMI108298403(CROT)
CSYR103263645(CROT)
MMUR105879364(CROT)
LCAT123647325(CROT)
PCOQ105809671(CROT)
OGA100941306(CROT)
MMU74114(Crot)
MCAL110294643(Crot)
MPAH110316407(Crot)
RNO83842(Crot)
MCOC116097476(Crot)
ANU117720598(Crot)
MUN110555237(Crot)
CGE100750995(Crot)
MAUA101826835(Crot)
PROB127214205(Crot)
PLEU114687552(Crot)
MORG121434739 121459029
MFOT126500097
AAMP119803776(Crot)
NGI103725174(Crot)
HGL101716437(Crot)
CPOC100722629(Crot)
CCAN109695711(Crot)
DORD105992949(Crot)
DSP122111853(Crot)
PLOP125346966(Crot)
NCAR124990758
MMMA107156293(Crot)
OCU100355549 127482691
OPI101525413(CROT)
TUP102478805(CROT)
GVR103604799(CROT)
CFA482283(CROT)
CLUD112674996(CROT)
VVP112935065(CROT)
VLG121474647(CROT)
NPO129498200(CROT)
AML100475120(CROT)
UMR103658682(CROT)
UAH113259454(CROT)
UAR123789333(CROT)
ELK111155283
LLV125081043
MPUF101685728(CROT)
MNP132015102(CROT)
MLK131829330(CROT)
NVS122904774(CROT)
ORO101367784(CROT)
EJU114222147(CROT)
ZCA113911932(CROT)
MLX118020710(CROT)
NSU110580162(CROT)
LWW102733928(CROT)
FCA101096799(CROT)
PYU121028034(CROT)
PCOO112866559(CROT)
PBG122487836(CROT)
LRUF124524396
PTG102972245(CROT)
PPAD109263645(CROT)
PUC125929870
AJU106987584
HHV120222232(CROT)
BTA281092(CROT)
BOM102278173(CROT)
BBUB102391500(CROT)
BBIS105002499(CROT)
CHX102178596(CROT)
OAS101111626(CROT)
BTAX128046662(CROT)
ODA120878099(CROT)
CCAD122438232(CROT)
MBEZ129552322(CROT)
SSC100521142(CROT)
CFR102512006(CROT)
CBAI105062362(CROT)
CDK105087356(CROT)
VPC102533285(CROT)
BACU103003725(CROT)
LVE103087959(CROT)
OOR101277059(CROT)
DLE111182205(CROT)
PCAD102986912(CROT)
PSIU116759580(CROT)
NASI112395341(CROT)
ECB100050111(CROT)
EPZ103541520(CROT)
EAI106844005(CROT)
MYB102246466(CROT)
MYD102755354(CROT)
MMYO118666262(CROT)
MLF102422510(CROT)
MNA107541722(CROT)
PKL118714340(CROT)
EFUS103293164(CROT)
HAI109371297(CROT)
DRO112303552(CROT)
SHON119000976(CROT)
AJM119037194(CROT)
PDIC114508132(CROT)
PHAS123811965(CROT)
MMF118620378(CROT)
RFQ117012092(CROT)
PPAM129063078(CROT)
PALE102880644(CROT)
PGIG120615076(CROT)
PVP105294815(CROT)
RAY107512459(CROT)
MJV108409489(CROT)
TOD119244692(CROT)
SARA101550473(CROT)
LAV100673752(CROT)
TMU101348777
ETF101637941(CROT)
DNM101425223(CROT)
MDO100027224(CROT)
GAS123250518(CROT)
SHR100934458(CROT)
AFZ127563963
PCW110209192(CROT)
OAA100077745
GGA420533(CROT)
PCOC116243189(CROT)
MGP100548491(CROT)
CJO107309018(CROT)
TPAI128086384(CROT)
LMUT125695990(CROT)
NMEL110393968(CROT)
APLA101793765(CROT)
ACYG106039688(CROT)
CATA118247481(CROT)
AFUL116486344(CROT)
TGU100231530(CROT)
LSR110482466(CROT)
SCAN103812799(CROT)
PMOA120503848(CROT)
OTC121338151(CROT)
PRUF121353100(CROT)
GFR102036972(CROT)
FAB101816162(CROT)
OMA130249521(CROT)
PHI102110439(CROT)
PMAJ107198602(CROT)
CCAE111924183(CROT)
CCW104689198(CROT)
CBRC103612275(CROT)
ETL114065105(CROT)
ZAB102073912(CROT)
ACHL103797930
SVG106852797(CROT)
MMEA130583671(CROT)
HRT120749954(CROT)
FPG101919746(CROT)
FCH102049905(CROT)
CLV102095452(CROT)
EGZ104128762(CROT)
NNI104022901(CROT)
PCRI104024075
PLET104613800(CROT)
EHS104512323(CROT)
PCAO104042125(CROT)
ACUN113476613(CROT)
TALA104369101(CROT)
PADL103922455(CROT)
AFOR103895941(CROT)
ACHC115339414(CROT)
HALD104316171(CROT)
HLE104836503(CROT)
AGEN126037759
GCL127013234
CCRI104164666(CROT)
CSTI104549317(CROT)
CMAC104476374(CROT)
MUI104547062(CROT)
BREG104638411(CROT)
FGA104073885(CROT)
GSTE104250690
LDI104344624(CROT)
MNB103771967(CROT)
OHA104332507(CROT)
NNT104407764(CROT)
SHAB115612556(CROT)
DPUB104306987(CROT)
PGUU104465745(CROT)
ACAR104529260(CROT)
CPEA104392210(CROT)
AVIT104267035(CROT)
CVF104289926(CROT)
RTD128905827(CROT)
CUCA104057705(CROT)
TEO104379421
BRHI104501354(CROT)
AAM106483608(CROT)
AROW112967006(CROT)
NPD112947352(CROT)
TGT104580900(CROT)
DNE112982317(CROT)
SCAM104144113(CROT)
ASN102386610(CROT)
AMJ102558111(CROT)
CPOO109308405(CROT)
GGN109291371(CROT)
PSS102461470(CROT)
CMY102941072(CROT)
CCAY125631397(CROT)
DCC119850993(CROT)
CPIC101942862(CROT)
TST117872177(CROT)
CABI116839972(CROT)
MRV120399501(CROT)
ACS100564060(crot)
ASAO132778876(CROT)
PVT110070292(CROT)
SUND121934122(CROT)
PBI103065388(CROT)
PMUR107283318(CROT)
CTIG120302671(CROT)
TSR106537910(CROT)
PGUT117655221(CROT)
APRI131196644(CROT)
PTEX113446470(CROT)
NSS113421117(CROT)
VKO123020653(CROT)
PMUA114607874(CROT)
PRAF128423917(CROT)
ZVI118091954(CROT)
HCG128330719(CROT)
GJA107124960(CROT)
STOW125440774(CROT)
EMC129337487(CROT)
XLA108719881(crot.S)
XTR733879(crot)
NPR108795594(CROT)
RTEM120939956(CROT)
BBUF121002899(CROT)
BGAR122938496(CROT)
MUO115468249(CROT)
GSH117354190(CROT)
DRE553204(crot)
SRX107717792 107738865
SANH107681585 107689876
SGH107549228 107597963
CCAR109082828(crot) 109106454
CAUA113059127 113116610
CGIB127975066 128030809
PTET122360287(crot)
LROH127178221(crot)
OMC131521270(crot)
PPRM120484666(crot)
RKG130069260(crot)
MAMB125243437(crot)
CIDE127497687
MASI127452999
TROS130557622(crot)
TDW130432359(crot)
MANU129448101(crot)
IPU108256531
IFU128599574(crot)
PHYP113532856(crot)
SMEO124375297(crot)
TFD113658677(crot)
TVC132839980(crot)
AMEX103046237(crot)
CMAO118798644(crot)
EEE113577078(crot)
CHAR105891923(crot)
TRU101075450(crot)
TFS130532267(crot)
TNGGSTEN00034002G001
LCO104923077 104940192
TBEN117480478 117480600 117480601
CGOB115020729(crot)
PGEO117451337(crot)
GACU117554056
ELY117266273(crot)
EFO125892802(crot)
PLEP121945831(crot)
SLUC116049506(crot)
ECRA117946867(crot)
ESP116691802(crot)
PFLV114557953(crot)
GAT120810340(crot) 120810341
PPUG119197977(crot) 119197978
AFB129110290(crot)
CLUM117745035(crot)
MSAM119897635(crot)
SCHU122882214(crot)
CUD121513383(crot)
ALAT119005499(crot)
MZE101470173
ONL100701298(acbd7)
OLA101171357(crot)
OML112143959(crot)
XMA102224261(crot)
XCO114141598(crot)
XHE116717009(crot)
PRET103478127(crot)
PFOR103140838(acbd7)
PLAI106940409(crot)
PMEI106929186(acbd7)
GAF122831216(crot)
CVG107096303(crot)
CTUL119772737(crot)
GMU124866095(crot)
NFU107379651(crot)
KMR108241122(crot)
ALIM106522589(crot)
NWH119409410(crot)
AOCE111581712(crot)
MCEP125016380(croT)
POV109633457(crot)
SSEN122774220(crot)
HHIP117777368
HSP118113677
LCF108889589
SDU111237186(crot)
SLAL111650837(crot)
XGL120784794(crot)
HCQ109528977(acbd7)
SSCV125975380
SBIA133501380
PEE133401276
BPEC110163072 110163075
MALB109964164(crot)
BSPL114842423
SJO128366788(crot)
SASA106576069 106606005
STRU115177235 115187336 115187353
OTW112222698 112225585 112225612
OMY110507826 110534183
OGO123998275 124017065
ONE115113758 115146783 115146876
OKI109884780 109905745 116352987
OKE118376271
SALP112077972
SNH120031181 120048783 120048785
CCLU121542678 121543229 121543230
ELS105018942(crot)
SFM108940735(crot)
PKI111860652(crot)
AANG118211128(crot)
LOC102684076(crot)
PSPA121313183 121315000
ARUT117400292(crot)
PSEX120515462(crot)
LCM102358236(CROT)
CMK103181560(crot)
RTP109914454(crot)
CPLA122550318(crot)
HOC132815773(crot)
LERI129709341(crot)
PMRN116941119(CROT)
LRJ133344706(CROT)
BFO118407980 118407990 118424118 118424119 118424330 118424334 118424498 118427318 118430885
BBEL109478028 109478823 109486559
CIN100178156 100178681
SCLV120338901 120343210 120343215
SPU580492 585404
LPIC129274804 129281711
APLC110985552
AJC117109207
SKO100371063 100376850 100379081 102801069 102804985 102806374
DMEDmel_CG12428(CROT)
DER6554387
DSE6618707
DSIDsimw501_GD29096(Dsim_GD29096)
DYADyak_GE10545
DAN6501465
DSR110177312
DPO4800672
DPE6595181
DMN108155278
DWI6647023
DGR6568645
DMODmoj_GI10740
DAZ108620762
DNV108651568
DHE111593234
DVI6633212
CCAT101459927
BOD106619588
BDR105227584
RZE108363623
TDA119680486
MDE101888731
SCAC106084480
LCQ111675773
LSQ119600897 119601573
GFS119638773
ECOE129941801
HIS119651017 119651018
AGA1273639
ACOZ120948049
AARA120902041
AMER121588328
ASTE118508480
AFUN125762055
AMOU128297206
AALI118458975
AAG5566097
AALB109397288 115266637
CQUCpipJ_CPIJ005329
CPII120431712
BCOO119067949
DCI113465332
NLU111047633
HVI124359523
PHUPhum_PHUM025470
FOC113218447
TPAL117641402
IEL124164358
PVM113813496
PJA122251825
PCHN125036115
PMOO119594193
HAME121872648
PCLA123759403
CQD128703211
PTRU123506696
ESN126991100
HAZT108674415
PPOI119109273
DSV119441543
RSAN119386689
RMP119178230
VDE111248150
VJA111259880
TUT107363886
CSCU111622241
PTEP107437700
UDV129225995
SDM118204696
LPOL106466459
CELCELE_F41E7.6(F41E7.6) CELE_T20B3.1(T20B3.1)
CBRCBG_17205 CBG_23894
CRQGCK72_019819 GCK72_023554
NAINECAME_03714
LGILOTGIDRAFT_226052
PVUL126807698
PCAN112564556
BGT106059629 106068542
GAE121381837
HRF124135048
HRJ124260565
CRG105325406
CVN111112801 111113258 111113259
CANU128163218
MYI110461181 110461182
PMAX117343711 117343902
MCAF127731251
MMER123531015
RPHI132712915
DPOL127855167 127855772
OBI106877705
OSN115216450
LAK106156438 106171270
NVE5514354
EPA110239307
ATEN116304492
ADF107331942
AMIL114961517
PDAM113685234
SPIS111334755
DGT114517480
XEN124440835
HMG100205473
HSY130622038
PIFPITG_01418
PSOJPHYSODRAFT_559750
SPARSPRG_15834
 » show all
Reference
1  [PMID:6436243]
  Authors
Farrell SO, Fiol CJ, Reddy JK, Bieber LL
  Title
Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
  Journal
J Biol Chem 259:13089-95 (1984)
  Sequence
[mmu:74114]
Reference
2  [PMID:3342008]
  Authors
Healy MJ, Kerner J, Bieber LL.
  Title
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
  Journal
Biochem J 249:231-7 (1988)
DOI:10.1042/bj2490231
Reference
3  [PMID:6630173]
  Authors
Miyazawa S, Ozasa H, Osumi T, Hashimoto T.
  Title
Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
  Journal
J Biochem (Tokyo) 94:529-42 (1983)
DOI:10.1093/oxfordjournals.jbchem.a134384
  Sequence
[rno:83842]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.137
IUBMB Enzyme Nomenclature: 2.3.1.137
ExPASy - ENZYME nomenclature database: 2.3.1.137
BRENDA, the Enzyme Database: 2.3.1.137
CAS: 39369-19-2

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