Entry
Name
carnitine O-octanoyltransferase;
medium-chain/long-chain carnitine acyltransferase;
carnitine medium-chain acyltransferase;
easily solubilized mitochondrial carnitine palmitoyltransferase;
overt mitochondrial carnitine palmitoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
octanoyl-CoA:L-carnitine O-octanoyltransferase
Reaction(IUBMB)
octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine [RN:
R03779 ]
Reaction(KEGG)
Substrate
Product
Comment
Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC
2.3.1.7 (carnitine O-acetyltransferase) and EC
2.3.1.21 (carnitine O-palmitoyltransferase).
History
EC 2.3.1.137 created 1992
Orthology
K05940 carnitine O-octanoyltransferase
Genes
MORG : 121434739 121459029
SANH : 107681585 107689876
CCAR : 109082828(crot) 109106454
CAUA : 113059127 113116610
CGIB : 127975066 128030809
TBEN : 117480478 117480600 117480601
GAT : 120810340(crot) 120810341
PPUG : 119197977(crot) 119197978
BPEC : 110163072 110163075
SASA : 106576069 106606005
STRU : 115177235 115187336 115187353
OTW : 112222698 112225585 112225612
ONE : 115113758 115146783 115146876
OKI : 109884780 109905745 116352987
SNH : 120031181 120048783 120048785
CCLU : 121542678 121543229 121543230
PSPA : 121313183 121315000
BFO : 118407980 118407990 118424118 118424119 118424330 118424334 118424498 118427318 118430885
BBEL : 109478028 109478823 109486559
SCLV : 120338901 120343210 120343215
LPIC : 129274804 129281711
SKO : 100371063 100376850 100379081 102801069 102804985 102806374
DSI : Dsimw501_GD29096(Dsim_GD29096)
AALB : 109397288 115266637
CEL : CELE_F41E7.6(F41E7.6) CELE_T20B3.1(T20B3.1)
CRQ : GCK72_019819 GCK72_023554
CVN : 111112801 111113258 111113259
PMAX : 117343711 117343902
DPOL : 127855167 127855772
» show all
Taxonomy
Reference
Authors
Farrell SO, Fiol CJ, Reddy JK, Bieber LL
Title
Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
Journal
J Biol Chem 259:13089-95 (1984)
Sequence
Reference
Authors
Healy MJ, Kerner J, Bieber LL.
Title
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
Journal
Reference
Authors
Miyazawa S, Ozasa H, Osumi T, Hashimoto T.
Title
Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.3.1.137