KEGG   ENZYME: 2.3.1.158
Entry
EC 2.3.1.158                Enzyme                                 
Name
phospholipid:diacylglycerol acyltransferase;
PDAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase
Reaction(IUBMB)
phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol [RN:R05333]
Reaction(KEGG)
R05333
Substrate
phospholipid [CPD:C00865];
1,2-diacyl-sn-glycerol [CPD:C00641]
Product
lysophospholipid [CPD:C06254];
triacylglycerol [CPD:C00422]
Comment
This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid.
History
EC 2.3.1.158 created 2001
Pathway
ec00561  Glycerolipid metabolism
ec01100  Metabolic pathways
Orthology
K00679  phospholipid:diacylglycerol acyltransferase
Genes
ATHAT3G44830 AT5G13640(PDAT)
ALY9309690 9313438
CRB17881928 17885438
CSAT104705618 104735371 104769582 104780334 104790735
EUSEUTSA_v10002852mg EUTSA_v10012888mg
BRP103846553 103850885
BNA106372279 106377188 106406534 111211845
BOE106318490 106327439
RSZ108817295 108842067
THJ104799356 104809891 104814810
CPAP110808547 110817685 110818323
CIT102608065 102609133 102609799
CICCICLE_v10025070mg CICLE_v10025078mg CICLE_v10027727mg
PVY116120024 116142184 116146808
MINC123199205 123200792 123211318 123219550
TCC18588322 18590424 18596196
GRA105772831 105774265 105784202 105792333 105792937 105799046
GHI107891726 107897707 107901080 107932867 107941265 107944192 107947285 107949699 107953304 107954163 107960298 121204773
GAB108456991 108458391 108470153 108474009 108480395 108485128
DZI111274675 111279003 111286760 111299177 111303069 111303764
EGR104421248 104422999 104436439
GMX100779225 100800857 100803760 100806313 100812643
GSJ114372974 114379317 114382442 114390510 114392747 114418155
PVUPHAVU_003G133000g PHAVU_010G132900g PHAVU_011G088800g
VRA106769440 106774144
VAR108319333 108338425
VUN114166844 114178533
CCAJ109799093 109802310 109808306
APRC113846357 113849576 113860043
MTR25492334 25500534
CAM101497807 101499408 101505056
LJALj3g3v2656650.1(Lj3g3v2656650.1) Lj4g3v2179270.1(Lj4g3v2179270.1)
ADU107457657 107464761 107479082
AIP107618017 107634440 107643486
AHF112710451 112723677 112735910 112770407 112775717
LANG109334037 109347629 109355287 109356249
FVE101301468 101311410
RCN112163750 112187750
PPER18771381 18774807
PMUM103326545 103340552
PAVI110749222 110755303
PDUL117631934 117634845
MDM103400853 103448013 103450792
PXB103929853 103932552 103951912
ZJU107403549 107410573 107424140
MNT21396621 21397235 21409968
CSV101215610 101222563
CMO103497986 103500706
BHJ120085798 120088742
MCHA111011365 111018295
CMAX111484072 111488585 111494451
CMOS111448684 111456080 111464287
CPEP111777293 111778524 111807354
RCU8266990 8272509 8284674
JCU105631411 105637340 105637933(PDAT)
HBR110632849 110635770 110641537 110651489 110668138
MESC110612221 110613312 110613532 110626552 110626764
POP18098005 7475706 7490955
PEU105111967 105118354 105133404 105136421
PALZ118034818 118038074 118045532 118060023
JRE108985608 109000668 109005305 109008819
QSU111992758 112011200 112012906 112023522
QLO115976039 115976040 115989696
TWL119993493 120002366 120002391
VVI100243077 100256634 100259274
VRI117915678 117922549 117925314
SLY101258674 101259322 101261928 101263223 101266485
SPEN107004164 107014474 107021662 107022891 107024408
SOT102586946 102590232 102597079 102597924 102606040
SSTN125844671 125857978 125872487 125875158 125876187
CANN107848184 107861698 107874787 107875629 107877860
NTA107768032 107775478 107782802 107789323 107809139 107811062 107815607 107818243
NSY104220307 104221715 104236791 104239807 104240673
NTO104090483 104097532 104116567 104121161
NAU109211607 109214649 109217286 109218871 109242616
INI109186432 109187504 109193143
ITR116009903 116013955 116014715
SIND105157789 105163255 105169966 105173654
OEU111401505 111401783
EGT105951305 105958532 105971047 105975942
SSPL121744432 121745022 121767668 121790702 121794181 121797749 121811371 121811380
HAN110886458 110893689 110904203 110909071 118490100
ECAD122595117 122595250 122603264 122607890
LSV111892640 111899140 111901442 111905326 111910335
CCAV112500771 112511716 112516913 112516986 112522263
DCR108192584 108206149 108213502 108223304 108227780
CSIN114270756 114276665 114291097 114296637
BVG104883605 104899770
SOE110793733 110803768
CQI110683011 110684360 110688112 110715985
NNU104600613 104609357 104612529
MING122064870 122086945
TSS122656175 122667478
PSOM113314070 113321076 113347605 113350354 113351133 113352849
NCOL116262343
OSA4347190
DOSAOs09t0444200-01(Os09g0444200)
OBR102703714
BDI100835274
ATS109745768
TDC119301544 119309383
TAES123103717 123111938 123121495
TUA125509275
SBI8081010
ZMA100191489 100273525
SITA101769545
SVS117843960
PVIR120660811 120680373
PHAI112880526
PDA103708654
EGU105041806
MUS103977610 103998045
DCT110096119
PEQ110022551
AOF109823033 109844472
ATR18439382 18441499
SMOSELMODRAFT_164869 SELMODRAFT_171888
PPP112275614
CRECHLRE_02g106400v5
VCNVOLCADRAFT_97885
MNGMNEG_3131
CSLCOCSUDRAFT_37169
OLUOSTLU_1469
OTAOT_ostta09g03210
BPGBathy10g01290
MISMICPUN_58725
MPPMICPUCDRAFT_58904
SCEYNR008W(LRO1)
SEUBDI49_4743
SPAOSPAR_N03100
AGOAGOS_AFL179C
ERCEcym_2120
KLAKLLA0_F06380g
KMXKLMA_60455(LRO1)
LTHKLTH0A05742g
ZROZYRO0C05478g
CGRCAGL0I05786g
NCSNCAS_0G00980(NCAS0G00980)
NDINDAI_0F01110(NDAI0F01110)
TPFTPHA_0D03660(TPHA0D03660)
TBLTBLA_0A02430(TBLA0A02430)
TDLTDEL_0A07120(TDEL0A07120)
TGBHG536_0A08690
KAFKAFR_0F00910(KAFR0F00910)
KNGKNAG_0D00600(KNAG0D00600)
ZMKHG535_0A06970
PPAPAS_chr2-1_0878
DHADEHA2D09922g
PICPICST_72946(LRO1)
PGUPGUG_04692
SPAASPAPADRAFT_132946
LELLELG_01378
CALCAALFM_C100870WA(LRO1)
CTPCTRG_04390
COTCORT_0B11180
CDUCD36_00820
CTENCANTEDRAFT_92085
YLIYALI0E16797g
CLUCLUG_00975
CLUSA9F13_09g00253
CAURCJI97_005022
SLBAWJ20_3581(LRO1)
PKZC5L36_0A12660
BNNFOA43_000117
BBRXBRETT_000982
OPAHPODL_01811
SLUDSCDLUD_001195
NCRNCU02416
NTENEUTE1DRAFT85933(NEUTE1DRAFT_85933)
SMPSMAC_08306
PANPODANSg9241
TTTTHITE_2116760
MTMMYCTH_2309146
CTHRCTHT_0048370
MGRMGG_03560
PPEIPpBr36_06697
TMNUCRPA7_1931
SSCKSPSK_00461
FGRFGSG_06375
FPUFPSE_12276
FVRFVEG_05051
FOXFOXG_08128
NHENECHADRAFT_59755
TRETRIREDRAFT_121546
TRRM419DRAFT_98582
MAWMAC_04716
MAJMAA_04510
CMTCCM_01242
PLJVFPFJ_02264
VALVDBG_09717
VDAVDAG_09453
CFJCFIO01_08076
CLUPCLUP02_06211
CHIGCH63R_01158
SAPOSAPIO_CDS4514
ELAUCREL1_3852
PFYPFICI_03524
SSLSS1G_11136
BFUBCIN_02g05210(Bclro1)
MBEMBM_06753
PSCOLY89DRAFT_686481
GLZGLAREA_10021
ANIAN4992.2
AFMAFUA_3G09950
ACTACLA_037790
NFINFIA_067340
AORAO090003000514
ANGANI_1_1660144(An16g03640)
AFVAFLA_001177
ALUCAKAW2_70312S
ACHEACHE_20944S
APUUAPUU_30836S
PCSPc12g15540
PDPPDIP_76480
TMFPMAA_025850
TRGTRUGW13939_03288
CIMCIMG_03952
CPWCPC735_004070
UREUREG_01995
PBLPAAG_07904
PBNPADG_08171
ABEARB_01216
TVETRV_01292
AJEHCAG_05471
BGHBDBG_02489
PNOSNOG_03081
PTEPTT_20057
BZECOCCADRAFT_33431
BSCCOCSADRAFT_158418
BORCOCMIDRAFT_83639
AALTCC77DRAFT_947980
ZTRMYCGRDRAFT_73528
PFJMYCFIDRAFT_155012
FFUCLAFUR5_09068
BCOMBAUCODRAFT_109446
NPAUCRNP2_3325
TMLGSTUM_00000255001
SPOSPBC776.14(plh1)
CNECNL04710
CNBCNBI2140
CNGCNAG_05152
CGICGB_D2350W
TMSTREMEDRAFT_68093
TASAA1Q1_06453
TVSTRAVEDRAFT_56169
DSQDICSQDRAFT_132754
PCOPHACADRAFT_197922
SHSSTEHIDRAFT_60411
HIRHETIRDRAFT_57041
PSQPUNSTDRAFT_105867
ADLAURDEDRAFT_113617
FMEFOMMEDRAFT_16796
GTRGLOTRDRAFT_135908
LBCLACBIDRAFT_156742(PDAT)
CCICC1G_02002
ABPAGABI1DRAFT71227(AGABI1DRAFT_71227)
ABVAGABI2DRAFT204119(AGABI2DRAFT_204119)
PCUBJR316_0002060
MRRMoror_1504
SCMSCHCO_02631503(SCHCODRAFT_02631503)
CPUTCONPUDRAFT_57356
SLASERLADRAFT_447691
WSEWALSEDRAFT_59615
WICJ056_003834
UMAUMAG_00322
PFPPFL1_03662
MGLMGL_3156 MGL_3157
MRTMRET_2127
MSYMMSY001_2834
PGRPGTG_14693
MLRMELLADRAFT_88797
EHIEHI_099180(57.t00020)
ACANACA1_036290 ACA1_074840 ACA1_327920 ACA1_399790
PTIPHATRDRAFT_8860
FCYFRACYDRAFT_166543
TPSTHAPSDRAFT_261132(PDT1)
AAFAURANDRAFT_1287 AURANDRAFT_23177
PIFPITG_11965
PSOJPHYSODRAFT_355873
GTTGUITHDRAFT_159571
TBRTb11.01.4790
TBGTbgDal_XI14750
TCR506757.10 510359.340
LMALMJF_09_1040
LIFLINJ_09_1100
LDOLDBPK_091100
LMILMXM_09_1040
LBZLBRM_09_1100
LPANLPMP_091050
 » show all
Reference
1  [PMID:10829075]
  Authors
Dahlqvist A, Stahl U, Lenman M, Banas A, Lee M, Sandager L, Ronne H, Stymne S
  Title
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants.
  Journal
Proc Natl Acad Sci U S A 97:6487-92 (2000)
DOI:10.1073/pnas.120067297
  Sequence
[sce:YNR008W]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.158
IUBMB Enzyme Nomenclature: 2.3.1.158
ExPASy - ENZYME nomenclature database: 2.3.1.158
BRENDA, the Enzyme Database: 2.3.1.158
CAS: 288587-47-3

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