KEGG ENZYME: 2.3.1.167

ENZYME: 2.3.1.167

Entry

EC 2.3.1.167                Enzyme

Name

10-deacetylbaccatin III 10-O-acetyltransferase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:taxan-10beta-ol O-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III [RN:R06311]

Reaction(KEGG)

R06311

Substrate

acetyl-CoA [CPD:C00024];
10-deacetylbaccatin III [CPD:C11700]

Product

CoA [CPD:C00010];
baccatin III [CPD:C11900]

Comment

The enzyme will not acylate the hydroxy group at 1beta, 7beta or 13alpha of 10-deacetyl baccatin III, or at 5alpha of taxa-4(20),11-dien-5alpha-ol. May be identical to EC 2.3.1.163, 10-hydroxytaxane O-acetyltransferase.

History

EC 2.3.1.167 created 2002

Pathway

ec00904

Diterpenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K12926

10-deacetylbaccatin III 10-O-acetyltransferase

Reference

1 [PMID:10639122]

Authors

Walker K, Croteau R

Title

Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.

Journal

Proc Natl Acad Sci U S A 97:583-7 (2000)
DOI:10.1073/pnas.97.2.583

Sequence

[ag:AAF27621]

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.167

IUBMB Enzyme Nomenclature:

2.3.1.167

ExPASy - ENZYME nomenclature database:

2.3.1.167

BRENDA, the Enzyme Database:

2.3.1.167

CAS:	220946-63-4

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