KEGG ENZYME: 2.3.1.17

ENZYME: 2.3.1.17

Entry

EC 2.3.1.17                 Enzyme

Name

aspartate N-acetyltransferase;
aspartate acetyltransferase;
L-aspartate N-acetyltransferase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:L-aspartate N-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + L-aspartate = CoA + N-acetyl-L-aspartate [RN:R00487]

Reaction(KEGG)

R00487

Substrate

acetyl-CoA [CPD:C00024];
L-aspartate [CPD:C00049]

Product

CoA [CPD:C00010];
N-acetyl-L-aspartate [CPD:C01042]

History

EC 2.3.1.17 created 1965

Pathway

ec00250

Alanine, aspartate and glutamate metabolism

ec01100

Metabolic pathways

Orthology

K18309

aspartate N-acetyltransferase

Genes

HSA:	339983(NAT8L)

PTR:	107974150(NAT8L)

PPS:	100977888(NAT8L)

GGO:	101142106(NAT8L)

PON:	100436366(NAT8L)

NLE:	100587578(NAT8L)

MCC:	722359(NAT8L)

MCF:	102127634(NAT8L)

CSAB:

103246472(NAT8L)

CATY:

105585478(NAT8L)

PANU:

101008786(NAT8L)

TGE:	112624793(NAT8L)

RRO:	104678940(NAT8L)

RBB:	108532290(NAT8L)

TFN:	117085051(NAT8L)

PTEH:

111538984(NAT8L)

CJC:	100406799(NAT8L)

SBQ:	101052380(NAT8L)

CSYR:

103249834(NAT8L)

MMUR:

105856037(NAT8L)

LCAT:

123622068(NAT8L)

OGA:	100944894(NAT8L)

MMU:	269642(Nat8l)

MCAL:

110295151(Nat8l)

MPAH:

110330690(Nat8l)

RNO:	289727(Nat8l)

MCOC:

116070270(Nat8l)

MUN:	110557251(Nat8l)

CGE:	100769399(Nat8l)

MAUA:

101824782(Nat8l)

PLEU:

114694065(Nat8l)

MORG:

121436457 121459416

AAMP:

119805966(Nat8l)

NGI:	103741134(Nat8l)

HGL:	101707458(Nat8l)

CCAN:

109695013(Nat8l)

DSP:	122100684(Nat8l)

NCAR:

124995112

OCU:	108175775(NAT8L)

OPI:	101523904(NAT8L)

TUP:	102494078(NAT8L)

CFA:	612955(NAT8L)

CLUD:

112653332(NAT8L)

VVP:	112922629(NAT8L)

VLG:	121489679(NAT8L)

AML:	100464561(NAT8L)

UMR:	103676989(NAT8L)

UAH:	113245722(NAT8L)

UAR:	123777861(NAT8L)

ELK:

111148887

LLV:

125093466

MPUF:

101688058(NAT8L)

ORO:	101367617(NAT8L)

EJU:	114198313(NAT8L)

ZCA:	113925352(NAT8L)

MLX:	118010179(NAT8L)

FCA:	101083676(NAT8L)

PBG:	122479126(NAT8L)

PPAD:

109269771(NAT8L)

HHV:	120231840(NAT8L)

BTA:	614317(NAT8L)

BOM:	102287615(NAT8L)

BIU:	109560729(NAT8L)

BBUB:

102389914(NAT8L)

CHX:	108636240(NAT8L)

OAS:	101102905(NAT8L)

ODA:	120861829(NAT8L)

CCAD:

122428370(NAT8L)

SSC:	102158081(NAT8L)

CFR:	102505541(NAT8L)

CBAI:

105072218(NAT8L)

CDK:	105100865(NAT8L)

VPC:	102541577(NAT8L)

BACU:

103003310(NAT8L)

LVE:	103069339(NAT8L)

OOR:	101289374(NAT8L)

DLE:	111164816(NAT8L)

PCAD:

102980581(NAT8L)

PSIU:

116754724(NAT8L)

ECB:	100052893(NAT8L)

EPZ:	103556144(NAT8L)

EAI:	106823798(NAT8L)

MYB:	102252987(NAT8L)

MMYO:

118665515(NAT8L)

MNA:	107524115(NAT8L)

PKL:	118707168(NAT8L)

HAI:	109390963(NAT8L)

DRO:	112316663(NAT8L)

SHON:

118987723(NAT8L)

AJM:	119035604(NAT8L)

PDIC:

114489950(NAT8L)

PHAS:

123815593(NAT8L)

MMF:	118640241(NAT8L)

RFQ:	117022031(NAT8L)

PALE:

102896372(NAT8L)

PGIG:

120582900(NAT8L)

PVP:	105301860(NAT8L)

RAY:	107517990(NAT8L)

MJV:	108383897(NAT8L)

TOD:	119260757(NAT8L)

SARA:

101552313(NAT8L)

LAV:	100672904(NAT8L)

TMU:

101362053

DNM:

101424776

MDO:	100015872(NAT8L)

GAS:	123252478(NAT8L)

SHR:	100933681(NAT8L)

PCW:	110212180(NAT8L)

OAA:	100093218(NAT8L)

GGA:	422893(NAT8L)

PCOC:

116225745(NAT8L)

MGP:	100542220 116216607(NAT8L)

CJO:	107314038(NAT8L)

NMEL:

110397424(NAT8L)

APLA:

101793941(NAT8L)

ACYG:

106034395(NAT8L)

AFUL:

116488859(NAT8L)

TGU:	100224712(NAT8L)

LSR:	110473285(NAT8L)

SCAN:

103826119(NAT8L)

PMOA:

120509393(NAT8L)

OTC:	121335068(NAT8L)

PRUF:

121348572(NAT8L)

GFR:	102034013(NAT8L)

FAB:	101812899(NAT8L)

PHI:	102112532(NAT8L)

PMAJ:

107203555(NAT8L)

CCW:	104690786(NAT8L)

CBRC:

103611186(NAT8L)

ETL:	114059975(NAT8L)

ZAB:	102070888(NAT8L)

FPG:	101915368(NAT8L)

FCH:	102045888(NAT8L)

CLV:	102094826(NAT8L)

EGZ:	104130198(NAT8L)

NNI:	104018092(NAT8L)

PLET:

104617086

ACUN:

113479125(NAT8L)

TALA:

104362551(NAT8L)

PADL:

103920988(NAT8L)

ACHC:

115343627(NAT8L)

HALD:

104318328

CCRI:

104167625(NAT8L)

CSTI:

104560157

CMAC:

104487652

MUI:	104539417(NAT8L)

FGA:

104076467

GSTE:

104260939(NAT8L)

LDI:	104347394(NAT8L)

MNB:	103771578(NAT8L)

OHA:	104329625(NAT8L)

AAM:	106498694(NAT8L)

AROW:

112965518(NAT8L)

NPD:	112943030(NAT8L)

DNE:	112990795(NAT8L)

ASN:	102374815(NAT8L)

AMJ:	102561647(NAT8L)

CPOO:

109322250(NAT8L)

GGN:	109303904(NAT8L)

PSS:	102463198(NAT8L)

CMY:	102941545(NAT8L)

CPIC:

101954085(NAT8L)

TST:	117877578(NAT8L)

CABI:

116822239(NAT8L)

MRV:	120406715(NAT8L)

ACS:	100564143(nat8l)

PVT:	110085596(NAT8L)

SUND:

121926017(NAT8L)

PBI:	103061437(NAT8L)

PMUR:

107291443(NAT8L)

TSR:	106548468(NAT8L)

PGUT:

117664703(NAT8L)

VKO:	123032383(NAT8L)

PMUA:

114596960(NAT8L) 114596961

ZVI:	118096449(NAT8L)

GJA:	107121903(NAT8L)

STOW:

125437095(NAT8L)

XLA:	108697734(nat8l.L) 108706518(nat8l.S)

XTR:	100124940(nat8l)

NPR:	108798993(NAT8L)

RTEM:

120924373(NAT8L)

BBUF:

120990408(NAT8L)

BGAR:

122939423(NAT8L)

DRE:	564754(nat8l)

SRX:	107741469 107753918

SANH:

107668697 107691926

SGH:	107562319 107588165

CCAR:

109092952 109094149

CAUA:

113052112 113105696

PPRM:

120487613(nat8l)

MAMB:

125264536(nat8l)

IPU:	108267961(nat8l)

PHYP:

113540350(nat8l)

SMEO:

124387040(nat8l)

TFD:	113663119(nat8l)

AMEX:

103037639(nat8l)

EEE:	113578333(nat8l)

TRU:	101075784(nat8l)

TNG:	GSTEN00025906G001

LCO:	104932916(nat8l) 109141877

NCC:	104959669 104966448

CGOB:

115013875 115023755(nat8l)

ELY:	117254794 117272701(nat8l)

EFO:	125884135(nat8l) 125886581

PLEP:

121937863 121941540 121962236(nat8l) 121966475

SLUC:

116039639 116043293(nat8l)

ECRA:

117937081 117962101(nat8l)

ESP:	116705236 116707020(nat8l)

PFLV:

114545966(nat8l) 114562953

GAT:	120823021(nat8l) 120825478

PPUG:

119217619 119223484(nat8l)

MSAM:

119899926 119913182(nat8l)

CUD:	121504208(nat8l) 121508652

ALAT:

119026656(nat8l) 119033179

MZE:	101484234(nat8l)

ONL:	100693080(nat8l) 100696276

OAU:	116333149 116333569(nat8l)

OLA:	101173814(nat8l)

OML:	112137520 112156197(nat8l)

XMA:	102230667(nat8l)

XCO:	114157704(nat8l)

XHE:	116732935(nat8l)

PRET:

103475969(nat8l)

PFOR:

103145966(nat8l)

PLAI:

106944729(nat8l)

PMEI:

106932174(nat8l)

GAF:	122820376(nat8l)

CVG:	107085259(nat8l) 107098478

CTUL:

119773383(nat8l) 119786956

GMU:	124880694(nat8l)

NFU:	107377265(nat8l)

KMR:	108245912(nat8l)

ALIM:

106526425(nat8l)

NWH:	119416028(nat8l)

AOCE:

111567478(nat8l) 111583385

MCEP:

125003591(nat8l) 125004525

CSEM:

103388298(nat8l)

POV:	109627415 109642466(nat8l) 109645502

SSEN:

122766683(nat8l)

HHIP:

117752225(nat8l) 117771472

HSP:	118103050(nat8l)

LCF:	108900136 108903071(nat8l)

SDU:	111229439 111235643(nat8l)

SLAL:

111647165(nat8l) 111666665

XGL:	120797550(nat8l) 120799622

HCQ:	109508395(nat8l)

BPEC:

110171955(nat8l) 110175162

MALB:

109974402(nat8l)

BSPL:

114851418(nat8l)

SASA:

106577271 106577818 106608862(nat8l)

OTW:	112214619 112240169 112259900

OMY:	110500846 110512764 110518994 110531620

OGO:	124008602 124013596 124020764

ONE:	115124493 115133428(nat8l)

SALP:

111953083 112072449 112078622

SNH:	120030398 120049434

CCLU:

121572202(nat8l) 123482919

ELS:	105020548(nat8l)

SFM:	108932924(nat8l)

PKI:	111851005(nat8l)

AANG:

118232311(nat8l)

LOC:	102689105(nat8l)

PSPA:

121325436 121330806

ARUT:

117409041 117421411 117971004

LCM:	102362340(NAT8L)

CMK:	103183111(nat8l)

RTP:

109920501

BFO:	118409954 118423353

SCLV:

120347071

PCHN:

125044251

EPA:

110254767

DGT:

114516641

XEN:

124440641

CCP:	CHC_T00001523001

MRR:	Moror_7693

» show all

Reference

Authors

Goldstein, F.B.

Title

Biosynthesis of N-acetyl-L-aspartic acid.

Journal

J Biol Chem 234:2702-2706 (1959)

Reference

2 [PMID:6061408]

Authors

Knizley H Jr.

Title

The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder.

Journal

J Biol Chem 242:4619-22 (1967)

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.17

IUBMB Enzyme Nomenclature:

2.3.1.17

ExPASy - ENZYME nomenclature database:

2.3.1.17

BRENDA, the Enzyme Database:

2.3.1.17

CAS:

9029-99-6

DBGET integrated database retrieval system