KEGG ENZYME: 2.3.1.17

ENZYME: 2.3.1.17

Entry

EC 2.3.1.17                 Enzyme

Name

aspartate N-acetyltransferase;
aspartate acetyltransferase;
L-aspartate N-acetyltransferase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:L-aspartate N-acetyltransferase

Reaction(IUBMB)

acetyl-CoA + L-aspartate = CoA + N-acetyl-L-aspartate [RN:R00487]

Reaction(KEGG)

R00487

Substrate

acetyl-CoA [CPD:C00024];
L-aspartate [CPD:C00049]

Product

CoA [CPD:C00010];
N-acetyl-L-aspartate [CPD:C01042]

History

EC 2.3.1.17 created 1965

Pathway

ec00250

Alanine, aspartate and glutamate metabolism

ec01100

Metabolic pathways

Orthology

K18309

aspartate N-acetyltransferase

Genes

HSA:	339983(NAT8L)

PTR:	107974150(NAT8L)

PPS:	100977888(NAT8L)

GGO:	101142106(NAT8L)

PON:	100436366(NAT8L)

PPYG:

129035764(NAT8L)

NLE:	100587578(NAT8L)

HMH:	116456687(NAT8L)

SSYN:

129464806(NAT8L)

MCC:	722359(NAT8L)

MCF:	102127634(NAT8L)

MTHB:

126955578

MNI:	105483846(NAT8L)

CSAB:

103246472(NAT8L)

CATY:

105585478(NAT8L)

PANU:

101008786(NAT8L)

TGE:	112624793(NAT8L)

RRO:	104678940(NAT8L)

RBB:	108532290(NAT8L)

TFN:	117085051(NAT8L)

PTEH:

111538984(NAT8L)

CJC:	100406799(NAT8L)

SBQ:	101052380(NAT8L)

CIMI:

108311578(NAT8L)

ANAN:

105727162(NAT8L)

CSYR:

103249834(NAT8L)

MMUR:

105856037(NAT8L)

LCAT:

123622068(NAT8L)

PCOQ:

105826210(NAT8L)

OGA:	100944894(NAT8L)

MMU:	269642(Nat8l)

MCAL:

110295151(Nat8l)

MPAH:

110330690(Nat8l)

RNO:	289727(Nat8l)

MCOC:

116070270(Nat8l)

ANU:	117712806(Nat8l)

ASYL:

127696338(Nat8l)

MUN:	110557251(Nat8l)

CGE:	100769399(Nat8l)

MAUA:

101824782(Nat8l)

PROB:

127233645(Nat8l)

PLEU:

114694065(Nat8l)

MORG:

121436457 121459416

MFOT:

126500862

AAMP:

119805966(Nat8l)

NGI:	103741134(Nat8l)

HGL:	101707458(Nat8l)

CCAN:

109695013(Nat8l)

DSP:	122100684(Nat8l)

DMER:

138826511(Nat8l)

PLOP:

125364805(Nat8l)

NCAR:

124995112

MMMA:

107138892(Nat8l)

ITI:	101967626(Nat8l)

OCU:

108175775

OPI:	101523904(NAT8L)

TUP:	102494078(NAT8L)

GVR:	103587913(NAT8L)

CFA:	612955(NAT8L)

CLUD:

112653332(NAT8L)

VVP:	112922629(NAT8L)

VLG:	121489679(NAT8L)

NPO:	129510558(NAT8L)

AML:	100464561(NAT8L)

UMR:	103676989(NAT8L)

UAH:	113245722(NAT8L)

UAR:	123777861(NAT8L)

ELK:

111148887

LLV:

125093466

MPUF:

101688058(NAT8L)

MNP:	131999086(NAT8L)

MLK:	131827032(NAT8L)

NVS:	122919109(NAT8L)

ORO:	101367617(NAT8L)

EJU:	114198313(NAT8L)

ZCA:	113925352(NAT8L)

MLX:	118010179(NAT8L)

NSU:	110583043(NAT8L)

FCA:	101083676(NAT8L)

PBG:	122479126(NAT8L)

PVIV:

125159209(NAT8L)

LRUF:

124522603

LGF:	123596268(NAT8L)

AJU:

128314599

PPAD:

109269771(NAT8L)

PUC:

125923865

PLEZ:

122217273(NAT8L)

HHV:	120231840(NAT8L)

BTA:	614317(NAT8L)

BOM:	102287615(NAT8L)

BIU:	109560729(NAT8L)

BBUB:

102389914(NAT8L)

CHX:	108636240(NAT8L)

OAS:	101102905(NAT8L)

BTAX:

128050045(NAT8L)

CSUM:

138082423(NAT8L)

ODA:	120861829(NAT8L)

CCAD:

122428370(NAT8L)

MREE:

136152917(NAT8L)

OVR:	110151537(NAT8L)

MBEZ:

129561555(NAT8L)

SSC:	102158081(NAT8L)

CFR:	102505541(NAT8L)

CBAI:

105072218(NAT8L)

CDK:	105100865(NAT8L)

VPC:	102541577(NAT8L)

BACU:

103003310(NAT8L)

BMUS:

118895364(NAT8L)

LVE:	103069339(NAT8L)

OOR:	101289374(NAT8L)

LALB:

132520081(NAT8L)

GMF:	115863677(NAT8L)

DDP:	132426214(NAT8L)

DLE:	111164816(NAT8L)

PCAD:

102980581(NAT8L)

PSIU:

116754724(NAT8L)

PPHC:

136123911(NAT8L)

NASI:

112391377(NAT8L)

ECB:	100052893(NAT8L)

EPZ:	103556144(NAT8L)

EAI:	106823798(NAT8L)

MYB:	102252987(NAT8L)

MMYO:

118665515(NAT8L)

MDT:	132222439(NAT8L)

MYUM:

138998326(NAT8L)

PKL:	118707168(NAT8L)

EFUS:

103294573(NAT8L)

MNA:	107524115(NAT8L)

DRO:	112316663(NAT8L)

SHON:

118987723(NAT8L)

AJM:	119035604(NAT8L)

PDIC:

114489950(NAT8L)

PHAS:

123815593(NAT8L)

MMF:	118640241(NAT8L)

PPAM:

129077484(NAT8L)

HAI:	109390963(NAT8L)

RFQ:	117022031(NAT8L)

PALE:

102896372(NAT8L)

PGIG:

120582900(NAT8L)

PVP:	105301860(NAT8L)

RAY:	107517990(NAT8L)

MJV:	108383897(NAT8L)

TOD:	119260757(NAT8L)

SARA:

101552313(NAT8L)

SFUM:

130030761(NAT8L)

SETR:

126032035(NAT8L)

LAV:	100672904(NAT8L)

TMU:

101362053

ETF:	101643562(NAT8L)

DNM:

101424776

MDO:	100015872(NAT8L)

GAS:	123252478(NAT8L)

SHR:	100933681(NAT8L)

AFZ:

127539931

PCW:	110212180(NAT8L)

TVP:	118853644(NAT8L)

PBRV:

138150774(NAT8L)

MLAO:

141518167(NAT8L)

OAA:	100093218(NAT8L)

GGA:	422893(NAT8L)

PCOC:

116225745(NAT8L)

MGP:	100542220 116216607(NAT8L)

CJO:	107314038(NAT8L)

TPAI:

128080351(NAT8L)

LMUT:

125692270(NAT8L)

NMEL:

110397424(NAT8L)

APLA:

101793941(NAT8L)

ACYG:

106034395(NAT8L)

CATA:

118248330(NAT8L)

AFUL:

116488859(NAT8L)

TGU:	100224712(NAT8L)

LSR:	110473285(NAT8L)

SCAN:

103826119(NAT8L)

PMOA:

120509393(NAT8L)

OTC:	121335068(NAT8L)

PRUF:

121348572(NAT8L)

ATRC:

139599677(NAT8L)

GFR:	102034013(NAT8L)

FAB:	101812899(NAT8L)

OMA:	130252805(NAT8L)

PHI:	102112532(NAT8L)

PMAJ:

107203555(NAT8L)

CCW:	104690786(NAT8L)

CBRC:

103611186(NAT8L)

ACOE:

138110020(NAT8L)

ETL:	114059975(NAT8L)

ZAB:	102070888(NAT8L)

ZLE:	135446448(NAT8L)

SVG:	106865254(NAT8L)

MMEA:

130578155(NAT8L)

HRT:	120753251(NAT8L)

SATI:

136360265(NAT8L)

CCIC:

134044209(NAT8L)

FPG:	101915368(NAT8L)

FCH:	102045888(NAT8L)

CCRI:

104167625(NAT8L)

NNT:	104412368(NAT8L)

SHAB:

115610716(NAT8L)

ACUN:

113479125(NAT8L)

TALA:

104362551(NAT8L)

ACHC:

115343627(NAT8L)

HALD:

104318328

HLE:	104837868(NAT8L)

AGEN:

126053163

HHAR:

128138928(NAT8L)

GCL:

127016267

CSTI:

104560157

LDI:	104347394(NAT8L)

MNB:	103771578(NAT8L)

DPUB:

104303579(NAT8L)

PPUS:

135179580(NAT8L)

EGZ:	104130198(NAT8L)

NNI:	104018092(NAT8L)

PADL:

103920988(NAT8L)

AFOR:

103904060(NAT8L)

FGA:

104076467

GSTE:

104260939(NAT8L)

CBOY:

140652083(NAT8L)

CLV:	102094826(NAT8L)

CNIC:

135988421(NAT8L)

MUI:	104539417(NAT8L)

PGUU:

104470670

PLET:

104617086

CMAC:

104487652

CUCA:

104060243(NAT8L)

TEO:	104374536(NAT8L)

BREG:

104644027(NAT8L)

OHA:	104329625(NAT8L)

CPEA:

104391028(NAT8L)

CVF:	104284234(NAT8L)

RTD:	128910559(NAT8L)

CRID:

134516025(NAT8L)

LMIC:

141743386(NAT8L)

AAM:	106498694(NAT8L)

AROW:

112965518(NAT8L)

NPD:	112943030(NAT8L)

TGT:	104572909(NAT8L)

DNE:	112990795(NAT8L)

ASN:	102374815(NAT8L)

AMJ:	102561647(NAT8L)

CPOO:

109322250(NAT8L)

GGN:	109303904(NAT8L)

PSS:	102463198(NAT8L)

CMY:	102941545(NAT8L)

CCAY:

125636239(NAT8L)

DCC:	119855007(NAT8L)

CPIC:

101954085(NAT8L)

TST:	117877578(NAT8L)

CABI:

116822239(NAT8L)

MRV:	120406715(NAT8L)

ACS:	100564143(nat8l)

ASAO:

132771380(NAT8L)

PVT:	110085596(NAT8L)

SUND:

121926017(NAT8L)

PBI:	103061437(NAT8L)

PMUR:

107291443(NAT8L)

CTIG:

120309920(NAT8L)

TSR:	106548468(NAT8L)

PGUT:

117664703 132710435(NAT8L)

PCAE:

139316644(NAT8L)

APRI:

131200080(NAT8L)

PTEX:

113449393(NAT8L)

NSS:	113425200(NAT8L)

VKO:	123032383(NAT8L)

PMUA:

114596960(NAT8L) 114596961

PRAF:

128413605(NAT8L)

ZVI:	118096449(NAT8L)

HCG:	128349860(NAT8L)

GJA:	107121903(NAT8L)

STOW:

125437095(NAT8L)

EMC:	129332886(NAT8L)

XLA:	108697734(nat8l.L) 108706518(nat8l.S)

XTR:	100124940(nat8l)

NPR:	108798993(NAT8L)

RTEM:

120924373(NAT8L)

ACAT:

141118477(NAT8L)

BBUF:

120990408(NAT8L)

BGAR:

122939423(NAT8L)

DTC:	141088405(NAT8L)

PWL:	138249733(NAT8L)

MUO:	115462583(NAT8L)

GSH:	117363324(NAT8L)

DRE:	564754(nat8l)

SRX:	107741469 107753918

SANH:

107668697 107691926

SGH:	107562319 107588165

CCAR:

109092952(nat8l) 122137947 122145605

CAUA:

113052112 113105696

CGIB:

127962132 128017125

PTET:

122348436(nat8l)

LROH:

127168349(nat8l)

GRF:	141331277(nat8l)

OMC:	131544312(nat8l)

PPRM:

120487613(nat8l)

RKG:	130102643(nat8l)

MAMB:

125264536(nat8l)

CIDE:

127516247

CERY:

137030967(nat8l)

MASI:

127411728 127442657

TROS:

130557571(nat8l)

TDW:	130427103(nat8l)

MANU:

129440479(nat8l)

PDAB:

135730792(nat8l)

IPU:

108267961

IFU:	128610286(nat8l)

PHYP:

113540350(nat8l)

SMEO:

124387040(nat8l)

TFD:	113663119(nat8l)

TVC:	132848001(nat8l)

CGAR:

128531784(nat8l)

NGRA:

132889021(nat8l)

TRN:	134311703(nat8l)

AMEX:

103037639(nat8l)

CMAO:

118825556(nat8l)

EEE:	113578333(nat8l)

CHAR:

105904563(nat8l) 116218338

SPIL:

134059996(nat8l) 134100749

ASAD:

121689723(nat8l) 121715840

TRU:	101075784(nat8l)

TFS:	130523455(nat8l)

TNG:	GSTEN00025906G001

LCO:	104932916(nat8l) 109141877

NCC:	104959669 104966448

TBEN:

117498120(nat8l)

CGOB:

115013875 115023755(nat8l)

PGEO:

117463874(nat8l)

GACU:

117539222(nat8l)

EMAC:

134872644(nat8l)

ELY:	117254794 117272701(nat8l)

EFO:	125884135(nat8l) 125886581

PLEP:

121937863 121941540 121962236(nat8l) 121966475

SLUC:

116039639 116043293(nat8l)

ECRA:

117937081 117962101(nat8l)

ESP:	116705236 116707020(nat8l)

PFLV:

114545966(nat8l) 114562953

GAT:	120823021(nat8l) 120825478

PPUG:

119217619 119223484(nat8l)

AFB:	129093533(nat8l) 129095401

CLUM:

117747946(nat8l)

PSWI:

130190201 130212032(nat8l)

CANA:

137792070(nat8l) 137793338

CVE:	137885883(nat8l) 137890546

MSAM:

119899926 119913182(nat8l)

SCHU:

122870017(nat8l) 122873486

CUD:	121504208(nat8l) 121508652

SPUL:

138600658(nat8l) 138604793

LMIX:

132954394 132958279(nat8l)

ALAT:

119026656(nat8l) 119033179

ASTR:

137590826(nat8l)

MZE:	101484234(nat8l)

ONL:	100693080(nat8l) 100696276

OAU:	116333149 116333569(nat8l)

OLA:	101173814(nat8l)

OML:	112137520 112156197(nat8l)

CSAI:

133420346(nat8l) 133453631

XMA:	102230667(nat8l)

XCO:	114157704(nat8l)

XHE:	116732935(nat8l)

PRET:

103475969(nat8l)

PFOR:

103145966(nat8l)

PLAI:

106944729(nat8l)

PMEI:

106932174(nat8l)

GAF:	122820376(nat8l)

PPRL:

129379431(nat8l)

CVG:	107085259(nat8l) 107098478

CTUL:

119773383(nat8l) 119786956

GMU:	124880694(nat8l)

NFU:	107377265(nat8l)

KMR:	108245912(nat8l)

ALIM:

106526425(nat8l)

NWH:	119416028(nat8l)

AOCE:

111567478(nat8l)

EJA:	138208125 138210658(nat8l)

BFRE:

138614413 138633027(nat8l)

MCEP:

125003591(nat8l) 125004525

CSEM:

103388298(nat8l)

POV:	109627415 109642466(nat8l) 109645502

SSEN:

122766683(nat8l)

SSOE:

131456217(nat8l)

HHIP:

117752225(nat8l) 117771472

HSP:	118103050(nat8l)

PPLT:

128430495(nat8l)

SMAU:

118290155(nat8l) 118312472

LCF:	108900136 108903071

SDU:	111229439 111235643(nat8l)

SLAL:

111647165(nat8l) 111666665

XGL:	120797550(nat8l) 120799622

HCQ:	109508395(nat8l)

SSCV:

125976145(nat8l)

SBIA:

133494342(nat8l) 133506628

PEE:	133398060(nat8l) 133404030

PTAO:

133472511(nat8l) 133476503

BPEC:

110171955(nat8l) 110175162

ENY:	140371478(nat8l) 140377976

MALB:

109974402(nat8l)

BSPL:

114851418(nat8l)

SJO:	128374544 128384009(nat8l)

SSCO:

133997300 134005688(nat8l)

GMH:	115529720(nat8l)

SASA:

106577271 106577818 106608862(nat8l)

STRU:

115189945 115194410 115198416(nat8l) 115202464

OTW:	112214619 112240169 112259900

OMY:	110500846 110512764 110518994 110531620

OGO:	124008602 124013596 124020764

ONE:	115124493 115133428(nat8l)

OKI:	109896437 109906864 116372057

OKE:	118368879 118383606 118392102

OMM:	135507184 135510478 135516218

OCLA:

139379405 139402814 139417128

SALP:

111953083 112072449 112078622

SNH:	120030398 120049434

SFON:

129835338 129841604 129841612 129865664

CCLU:

121572202(nat8l) 123482919

ELS:	105020548(nat8l)

OEP:	134010014(nat8l)

SFM:	108932924(nat8l)

PKI:	111851005(nat8l)

AANG:

118232311(nat8l)

AROT:

135259375(nat8l)

CCOG:

133134423(nat8l)

LOC:	102689105(nat8l)

PSPA:

121325436 121330806

ARUT:

117409041 117421411 117971004

PSEX:

120527843(nat8l)

LCM:	102362340(NAT8L)

CMK:	103183111(nat8l)

RTP:	109920501(nat8l)

HOC:	132826665(nat8l)

LERI:

129695368(nat8l)

HAKA:

140716453 140728885(nat8l)

PMRN:

116940424(NAT8L)

LRJ:

133343290

BFO:	118409954 118423353

SCLV:

120347071

PCHN:

125044251

EPA:

110254767

DGT:

114516641

XEN:

124440641

CCP:	CHC_T00001523001

MRR:	Moror_7693

» show all

Reference

Authors

Goldstein FB.

Title

Biosynthesis of N-acetyl-L-aspartic acid.

Journal

J Biol Chem 234:2702-2706 (1959)

Reference

2 [PMID:6061408]

Authors

Knizley H Jr.

Title

The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder.

Journal

J Biol Chem 242:4619-22 (1967)

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.17

IUBMB Enzyme Nomenclature:

2.3.1.17

ExPASy - ENZYME nomenclature database:

2.3.1.17

BRENDA, the Enzyme Database:

2.3.1.17

CAS:

9029-99-6

All links

Gene (348)   
   MGENES (203)   
   RefGene (145)   
Protein sequence (842)   
   UniProt (822)   
   SWISS-PROT (5)   
   RefSeq(pep) (15)   
DNA sequence (37)   
   RefSeq(nuc) (16)   
   GenBank (12)   
   EMBL (9)   
Protein domain (3)   
   InterPro (3)   
All databases (1230)   

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