Entry |
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Name |
phosphinothricin acetyltransferase;
PAT (ambiguous);
PPT acetyltransferase;
Pt-N-acetyltransferase
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Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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Sysname |
acetyl-CoA:phosphinothricin N-acetyltransferase
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Reaction(IUBMB) |
acetyl-CoA + phosphinothricin = CoA + N-acetylphosphinothricin [RN: R08938]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The substrate phosphinothricin is used as a nonselective herbicide and is a potent inhibitor of EC 6.3.1.2, glutamine synthetase, a key enzyme of nitrogen metabolism in plants [2].
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History |
EC 2.3.1.183 created 2007
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Pathway |
ec00440 | Phosphonate and phosphinate metabolism |
ec01110 | Biosynthesis of secondary metabolites |
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Orthology |
K03823 | phosphinothricin acetyltransferase |
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Genes |
» show all
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Reference |
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Authors |
Botterman J, Gossele V, Thoen C, Lauwereys M. |
Title |
Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins. |
Journal |
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Reference |
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Authors |
Droge-Laser W, Siemeling U, Puhler A, Broer I. |
Title |
The Metabolites of the Herbicide L-Phosphinothricin (Glufosinate) (Identification, Stability, and Mobility in Transgenic, Herbicide-Resistant, and Untransformed Plants). |
Journal |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 2.3.1.183 |
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