KEGG   ENZYME: 2.3.1.205
Entry
EC 2.3.1.205                Enzyme                                 
Name
fumigaclavine B O-acetyltransferase;
FgaAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:fumigaclavine B O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A [RN:R10200]
Reaction(KEGG)
R10200
Substrate
acetyl-CoA [CPD:C00024];
fumigaclavine B [CPD:C20437]
Product
CoA [CPD:C00010];
fumigaclavine A [CPD:C20436]
Comment
The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid produced by some fungi of the Trichocomaceae family.
History
EC 2.3.1.205 created 2012
Pathway
ec00901  Indole alkaloid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K19184  fumigaclavine B O-acetyltransferase
Genes
ANIAN9250.2
AFMAFUA_2G18020
ACTACLA_059750
ANGANI_1_1240084(An09g02790) ANI_1_2062144(An16g08610)
ALUCAKAW2_40331A AKAW2_70683S
ACHEACHE_11446A
APUUAPUU_20933A APUU_60002A APUU_60803A
TRGTRUGW13939_05969
Reference
1  [PMID:19672909]
  Authors
Liu X, Wang L, Steffan N, Yin WB, Li SM
  Title
Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B.
  Journal
Chembiochem 10:2325-8 (2009)
DOI:10.1002/cbic.200900395
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.205
IUBMB Enzyme Nomenclature: 2.3.1.205
ExPASy - ENZYME nomenclature database: 2.3.1.205
BRENDA, the Enzyme Database: 2.3.1.205

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