| Entry |
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| Name |
dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase;
VioB
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase
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| Reaction(IUBMB) |
acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [RN: R10174]
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| Reaction(KEGG) |
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| Substrate |
acetyl-CoA [CPD: C00024];
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose [CPD: C04268]
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| Product |
CoA [CPD: C00010];
dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose [CPD: C06018]
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| Comment |
The non-activated product, 4-acetamido-4,6-dideoxy-alpha-D-glucose, is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7.
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| History |
EC 2.3.1.209 created 2012
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| Pathway |
| ec00541 | Biosynthesis of various nucleotide sugars |
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| Orthology |
| K21379 | dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase |
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| Genes |
| TFT: | RI844_07055 RI844_07120 |
| SMIO: | CATMQ487_13220(vioB) |
| HCB: | HCBAA847_0832 HCBAA847_0839 |
| BTHR: | YBT1520_10510 YBT1520_30374 |
| BTHI: | BTK_10650 BTK_30179 |
| BWD: | CT694_10650 CT694_31475 |
| BALU: | QRY64_01625 QRY64_11870 |
| FPE: | Ferpe_0117 Ferpe_1105 |
| FIA: | NA23_00725 NA23_09235 |
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| Reference |
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| Authors |
Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L |
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| Title |
Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.3.1.209 |
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