KEGG   ENZYME: 2.3.1.216
Entry
EC 2.3.1.216                Enzyme                                 

Name
5,7-dihydroxy-2-methylchromone synthase;
pentaketide chromone synthase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
malonyl-CoA:malonyl-CoA malonyltransferase (5,7-dihydroxy-2-methyl-4H-chromen-4-one-forming)
Reaction(IUBMB)
5 malonyl-CoA = 5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O [RN:R10238]
Reaction(KEGG)
R10238
Substrate
malonyl-CoA [CPD:C00083]
Product
CoA [CPD:C00010];
5,7-dihydroxy-2-methyl-4H-chromen-4-one [CPD:C20462];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A polyketide synthase from the plant Aloe arborescens (aloe).
History
EC 2.3.1.216 created 2013
Orthology
K21385  5,7-dihydroxy-2-methylchromone synthase
Genes
AOF: 109833799
Reference
1  [PMID:15686354]
  Authors
Abe I, Utsumi Y, Oguro S, Morita H, Sano Y, Noguchi H
  Title
A plant type III polyketide synthase that produces pentaketide chromone.
  Journal
J Am Chem Soc 127:1362-3 (2005)
DOI:10.1021/ja0431206
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.216
IUBMB Enzyme Nomenclature: 2.3.1.216
ExPASy - ENZYME nomenclature database: 2.3.1.216
BRENDA, the Enzyme Database: 2.3.1.216

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