KEGG   ENZYME: 2.3.1.216
Entry
EC 2.3.1.216                Enzyme                                 
Name
5,7-dihydroxy-2-methylchromone synthase;
pentaketide chromone synthase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
malonyl-CoA:malonyl-CoA malonyltransferase (5,7-dihydroxy-2-methyl-4H-chromen-4-one-forming)
Reaction(IUBMB)
5 malonyl-CoA = 5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O [RN:R10238]
Reaction(KEGG)
R10238
Substrate
malonyl-CoA [CPD:C00083]
Product
CoA [CPD:C00010];
5,7-dihydroxy-2-methyl-4H-chromen-4-one [CPD:C20462];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A polyketide synthase from the plant Aloe arborescens (aloe).
History
EC 2.3.1.216 created 2013
Orthology
K21385  5,7-dihydroxy-2-methylchromone synthase
Genes
AOF: 109833799
Reference
1  [PMID:15686354]
  Authors
Abe I, Utsumi Y, Oguro S, Morita H, Sano Y, Noguchi H
  Title
A plant type III polyketide synthase that produces pentaketide chromone.
  Journal
J Am Chem Soc 127:1362-3 (2005)
DOI:10.1021/ja0431206
  Sequence
[ag:AAX35541]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.216
IUBMB Enzyme Nomenclature: 2.3.1.216
ExPASy - ENZYME nomenclature database: 2.3.1.216
BRENDA, the Enzyme Database: 2.3.1.216

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (4)   
   InterPro (4)   
All databases (16)   

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