Entry |
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Name |
2-acylglycerol O-acyltransferase;
acylglycerol palmitoyltransferase;
monoglyceride acyltransferase;
acyl coenzyme A-monoglyceride acyltransferase;
monoacylglycerol acyltransferase
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Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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Sysname |
acyl-CoA:2-acylglycerol O-acyltransferase
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Reaction(IUBMB) |
acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN: R01368]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.
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History |
EC 2.3.1.22 created 1972, modified 1986, modified 1989
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Pathway |
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Orthology |
K14456 | 2-acylglycerol O-acyltransferase 3 |
K14457 | 2-acylglycerol O-acyltransferase 2 |
K14458 | 2-acylglycerol O-acyltransferase 1 |
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Genes |
» show all
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Reference |
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Authors |
Manganaro F, Kuksis A. |
Title |
Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 2.3.1.22 |
ExPASy - ENZYME nomenclature database: | 2.3.1.22 |
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