| Entry |
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| Name |
GDP-perosamine N-acetyltransferase;
perB (gene name);
GDP-alpha-D-perosamine N-acetyltransferase
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
acetyl-CoA:GDP-4-amino-4,6-dideoxy-alpha-D-mannose N-acetyltransferase
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| Reaction(IUBMB) |
acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose = CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose [RN: R10514]
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| Reaction(KEGG) |
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| Substrate |
acetyl-CoA [CPD: C00024];
GDP-4-amino-4,6-dideoxy-alpha-D-mannose [CPD: C20638]
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| Product |
CoA [CPD: C00010];
GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose [CPD: C20672]
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| Comment |
D-Perosamine is one of several dideoxy sugars found in the O-antigen component of the outer membrane lipopolysaccharides of Gram-negative bacteria.
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| History |
EC 2.3.1.227 created 2013
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| Pathway |
| ec00541 | Biosynthesis of various nucleotide sugars |
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| Orthology |
| K17939 | GDP-perosamine N-acetyltransferase |
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| Genes |
| BREN: | KKHFBJBL_03056(perB) |
| SPAG: | sphantq_04703(perB) |
| SFLA: | SPHFLASMR4Y_02423(perB) |
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| Reference |
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| Authors |
Albermann C, Beuttler H |
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| Title |
Identification of the GDP-N-acetyl-d-perosamine producing enzymes from Escherichia coli O157:H7. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.3.1.227 |
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