KEGG   ENZYME: 2.3.1.24
Entry
EC 2.3.1.24                 Enzyme                                 

Name
sphingosine N-acyltransferase;
ceramide synthetase;
sphingosine acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acyl-CoA:sphingosine N-acyltransferase
Reaction(IUBMB)
acyl-CoA + sphingosine = CoA + a ceramide [RN:R01496]
Reaction(KEGG)
R01496;
(other) R02543 R06517
Substrate
acyl-CoA [CPD:C00040];
sphingosine [CPD:C00319]
Product
CoA [CPD:C00010];
ceramide [CPD:C00195]
Comment
Acts on sphingosine or its 2-epimer.
History
EC 2.3.1.24 created 1972
Pathway
ec00600  Sphingolipid metabolism
Reference
1  [PMID:5973195]
  Authors
Sribney M.
  Title
Enzymatic synthesis of ceramide.
  Journal
Biochim Biophys Acta 125:542-7 (1966)
DOI:10.1016/0005-2760(66)90042-7
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.24
IUBMB Enzyme Nomenclature: 2.3.1.24
ExPASy - ENZYME nomenclature database: 2.3.1.24
BRENDA, the Enzyme Database: 2.3.1.24
CAS: 37257-09-3

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