KEGG   ENZYME: 2.3.1.264Help
Entry
EC 2.3.1.264                Enzyme                                 

Name
beta-lysine N6-acetyltransferase;
ablB (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:(3S)-3,6-diaminohexanoate N6-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + (3S)-3,6-diaminohexanoate = CoA + (3S)-6-acetamido-3-aminohexanoate [RN:R11701]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
(3S)-3,6-diaminohexanoate [CPD:C01142]
Product
CoA [CPD:C00010];
(3S)-6-acetamido-3-aminohexanoate [CPD:C21604]
Comment
The enzyme is found in some methanogenic archaea and bacteria. In archaea it is induced under salt stress. The product, N6-acetyl-beta-L-lysine, serves as a compatible solute, conferring high salt resistance on the producing organisms.
History
EC 2.3.1.264 created 2017
Orthology
K21935  beta-lysine N6-acetyltransferase
Genes
SSE: Ssed_1816
LSD: EMK97_14325
PSEO: OM33_16210
PPHE: PP2015_1237
PLZ: S4054249_10800
PSPO: PSPO_b0325
PIN: Ping_1907
GEB: GM18_0332
GSB: GSUB_05960
PCA: Pcar_1402(ablB)
PPD: Ppro_1080
DEU: DBW_0847(yodP)
DDE: Dde_0188
DFL: DFE_1857
DAS: Daes_0846
DPI: BN4_11172
PPRF: DPRO_1392
DBA: Dbac_0210
DRT: Dret_0695
DPS: DP2160
SAT: SYN_02633
BMX: BMS_0904
BSU: BSU19700(yodP)
BSR: I33_2213
BSL: A7A1_2841
BSH: BSU6051_19700(yodP)
BSUT: BSUB_02122(yodP)
BSUL: BSUA_02122(yodP)
BSS: BSUW23_10540(yodP)
BST: GYO_2378
BSO: BSNT_08543(yodP)
BSQ: B657_19700(kamB)
BSX: C663_2028(yodP)
BLI: BL01429(yodP)
BLD: BLi02295(yodP)
BLH: BaLi_c23800(yodP)
BAY: RBAM_019530(ablB)
BAQ: BACAU_1954(yodP)
BYA: BANAU_2077(yodP)
BAMP: B938_10120
BAML: BAM5036_1885(yodP)
BAMA: RBAU_1922(kamB)
BAMN: BASU_1902(kamB)
BAMB: BAPNAU_1792(yodP)
BAMT: AJ82_11085
BAMY: V529_21760(yodP)
BMP: NG74_02032(yodP)
BAO: BAMF_2049(yodP)
BAZ: BAMTA208_07260(yodP)
BQL: LL3_02152(yodP)
BXH: BAXH7_01476(yodP)
BQY: MUS_2331(yodP)
BAMI: KSO_009580
BAMC: U471_20160
BAMF: U722_10650
BAN: BA_2298
BAR: GBAA_2298
BAT: BAS2143
BAI: BAA_2362
BANT: A16_23360
BANR: A16R_23620
BANS: BAPAT_2198
BANV: DJ46_1095(ablB)
BCE: BC2249
BCA: BCE_2332
BCQ: BCQ_2232
BCX: BCA_2379
BNC: BCN_2226
BCF: bcf_11510
BCER: BCK_23350
BTL: BALH_2060
BTT: HD73_2538
BTHI: BTK_12585
BTM: MC28_1468
BTI: BTG_08630
BTW: BF38_3499(ablB)
BWW: bwei_2747(yodP)
BMYO: BG05_3745(ablB)
BMYC: DJ92_4850(ablB)
BWD: CT694_12190(ablB)
BPU: BPUM_0610
BPUM: BW16_03365
BPUS: UP12_03400
BMQ: BMQ_4041
BMD: BMD_4026
BMEG: BG04_955(ablB)
BJS: MY9_2158
BACW: QR42_03285
BACP: SB24_18935
BACB: OY17_12890
BACY: QF06_08985
BACL: BS34A_21860(yodP)
BALM: BsLM_2096
BEO: BEH_06225
BGY: BGLY_2548
BKW: BkAM31D_12435(yodP)
BKO: CKF48_19595(ablB)
BALT: CFN77_03335(ablB)
BACQ: DOE78_15425(ablB)
ANM: GFC28_580(ablB)
AAMY: GFC30_1858(ablB)
ANL: GFC29_1044(ablB)
BLR: BRLA_c014500(yodP)
BAGR: BA6348_18640(ablB)
ASOC: CB4_04199(yodP)
COH: EAV92_13085(ablB)
PANC: E2636_15740(ablB)
LFB: C1X05_08465(ablB)
TVU: AB849_006385(ablB)
CBE: Cbei_2936
CBEI: LF65_01557
CPAT: CLPA_c13710(ablB)
CPAE: CPAST_c13710(ablB)
CSQ: CSCA_2502
CLD: CLSPO_c15730(ablB)
CTYK: CTK_C05930
CTAE: BGI42_06410(ablB)
HSC: HVS_06555(yodP)
EAC: EAL2_808p00700(yodP)
DRM: Dred_0739
DAE: Dtox_0601
DAU: Daud_0170
DEC: DCF50_p80
CBAR: PATL70BA_2535(ablB) PATL70BA_2912(ablB)
PSAC: PSM36_1052
DORI: FH5T_13975
ASX: CDL62_14110(ablB)
MARM: YQ22_05335
MARB: CJ263_11000(ablB)
FBE: FF125_10005(ablB)
CPC: Cpar_1398
PVI: Cvib_1365
PLT: Plut_1575
PAA: Paes_0800
PROS: CHL67_07370(ablB)
GTL: EP073_02610(ablB)
MMP: MMP0862(yodP)
MMD: GYY_05005
MAE: Maeo_0241
MAC: MA_3978
MBAR: MSBR2_3215
MMA: MM_0935
MMAC: MSMAC_0390
METM: MSMTP_0454
MHOR: MSHOH_0462
MBU: Mbur_0273
MMH: Mmah_1438
MPY: Mpsy_1922
MLA: Mlab_0344
MPI: Mpet_1465
MPD: MCP_1918
MEZ: Mtc_0927
 » show all
Taxonomy
Reference
1  [PMID:14532061]
  Authors
Pfluger K, Baumann S, Gottschalk G, Lin W, Santos H, Muller V
  Title
Lysine-2,3-aminomutase and beta-lysine acetyltransferase genes of methanogenic archaea are salt induced and are essential for the biosynthesis of Nepsilon-acetyl-beta-lysine and growth at high salinity.
  Journal
Appl Environ Microbiol 69:6047-55 (2003)
DOI:10.1128/AEM.69.10.6047-6055.2003
  Sequence
[mma:MM_0935]
Reference
2  [PMID:21538109]
  Authors
Muller S, Hoffmann T, Santos H, Saum SH, Bremer E, Muller V
  Title
Bacterial abl-like genes: production of the archaeal osmolyte N(epsilon)-acetyl-beta-lysine by homologous overexpression of the yodP-kamA genes in Bacillus subtilis.
  Journal
Appl Microbiol Biotechnol 91:689-97 (2011)
DOI:10.1007/s00253-011-3301-8
  Sequence
[bsu:BSU19700]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.264
IUBMB Enzyme Nomenclature: 2.3.1.264
ExPASy - ENZYME nomenclature database: 2.3.1.264
BRENDA, the Enzyme Database: 2.3.1.264

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