KEGG   ENZYME: 2.3.1.264
Entry
EC 2.3.1.264                Enzyme                                 
Name
beta-lysine N6-acetyltransferase;
ablB (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:(3S)-3,6-diaminohexanoate N6-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + (3S)-3,6-diaminohexanoate = CoA + (3S)-6-acetamido-3-aminohexanoate [RN:R11701]
Reaction(KEGG)
R11701
Substrate
acetyl-CoA [CPD:C00024];
(3S)-3,6-diaminohexanoate [CPD:C01142]
Product
CoA [CPD:C00010];
(3S)-6-acetamido-3-aminohexanoate [CPD:C21604]
Comment
The enzyme is found in some methanogenic archaea and bacteria. In archaea it is induced under salt stress. The product, N6-acetyl-beta-L-lysine, serves as a compatible solute, conferring high salt resistance on the producing organisms.
History
EC 2.3.1.264 created 2017
Orthology
K21935  beta-lysine N6-acetyltransferase
Genes
SSESsed_1816
SCAATUM17387_28340
LSDEMK97_14325
PSEOOM33_16210
PPHEPP2015_1237
PLZS4054249_10800
PSPOPSPO_b0325
PINPing_1907
FBLFbal_1214
GEMGM21_3127
GEBGM18_0332
GBNGEOBRER4_13340
GSBGSUB_05960
GERKP004_17565
GNTKP003_19225
PCAPcar_1402(ablB)
PACEA6070_05735
PPDPpro_1080
DESDSOUD_2507
DEUDBW_0847(yodP)
DVEDESUT3_13430
DFLDFE_1857
DDEDde_0188
DSADesal_3315
DAFDesaf_1115
DASDaes_0846
DPIBN4_11172
PPRFDPRO_1392
PSELGM415_01915(ablB)
DBADbac_0210
DRTDret_0695
DPSDP2160
DAKDaAHT2_0564
DATHRM2_44880
DWDDSCW_64840(yodP)
DALKDSCA_17980(yodP)
SATSYN_02633
BBAEFRD01_12570
BMXBMS_0904
BSUBSU19700(yodP)
BSRI33_2213
BSLA7A1_2841
BSHBSU6051_19700(yodP)
BSYI653_10220
BSUTBSUB_02122(yodP)
BSULBSUA_02122(yodP)
BSOBSNT_08543(yodP)
BSNBSn5_01230
BSQB657_19700(kamB)
BSXC663_2028(yodP)
BSPU712_10405
BSSBSUW23_10540(yodP)
BSTGYO_2378
BLIBL01429(yodP)
BLDBLi02295(yodP)
BLHBaLi_c23800(yodP)
BAYRBAM_019530(ablB)
BAQBACAU_1954(yodP)
BYABANAU_2077(yodP)
BAMPB938_10120
BQYMUS_2331(yodP)
BAMLBAM5036_1885(yodP)
BAMARBAU_1922(kamB)
BAMNBASU_1902(kamB)
BAMBBAPNAU_1792(yodP)
BAMTAJ82_11085
BAMYV529_21760(yodP)
BMPNG74_02032(yodP)
BAOBAMF_2049(yodP)
BAZBAMTA208_07260(yodP)
BQLLL3_02152(yodP)
BXHBAXH7_01476(yodP)
BAMIKSO_009580
BAMCU471_20160
BAMFU722_10650
BSIACWD84_11245(ablB)
BAEBATR1942_08570
BVMB9C48_09945
BSONS101395_02309(kamA)
BHTDIC78_20725(ablB)
BMOJHC660_20360(kamB)
BTEQG4P54_11305(ablB)
BIQAN935_10460
BANBA_2298
BARGBAA_2298
BATBAS2143
BAHBAMEG_2296
BAIBAA_2362
BAXH9401_2185
BANTA16_23360
BANRA16R_23620
BANSBAPAT_2198
BANHHYU01_11455
BANVDJ46_1095(ablB)
BCEBC2249
BCABCE_2332
BCZBCE33L2077
BCRBCAH187_A2406
BCBBCB4264_A2279
BCUBCAH820_2323
BCGBCG9842_B3044
BCQBCQ_2232
BCXBCA_2379
BALBACI_c22590
BNCBCN_2226
BCFbcf_11510
BCERBCK_23350
BCEFBcrFT9_01833
BCYBcer98_1686
BTKBT9727_2081
BTLBALH_2060
BTBBMB171_C2027
BTTHD73_2538
BTHRYBT1520_12415
BTHIBTK_12585
BTCCT43_CH2215
BTFYBT020_11750
BTMMC28_1468
BTGBTB_c23310
BTIBTG_08630
BTNBTF1_08750
BTHTH175_ch2249
BTHUYBT1518_12480
BTWBF38_3499(ablB)
BTHYAQ980_18375
BWEBcerKBAB4_2116
BWWbwei_2747(yodP)
BMYOBG05_3745(ablB)
BTYBtoyo_4881
BMYCDJ92_4850(ablB)
BBYCY96_10370
BWDCT694_12190(ablB)
BTROFJR70_08155(ablB)
BMOBMLA2C4_11485(ablB)
BNTGSN03_11025(ablB)
BPACLMD38_15265(ablB)
BPUBPUM_0610
BPUMBW16_03365
BPUSUP12_03400
BJSMY9_2158
BACIB1NLA3E_14065
BIFN288_16195
BMETBMMGA3_10140
GSTHW35_02725
BACWQR42_03285
BACPSB24_18935
BACBOY17_12890
BACYQF06_08985
BACLBS34A_21860(yodP)
BALMBsLM_2096
BGYBGLY_2548
BXIBK049_04740
BALTCFN77_03335(ablB)
BACSAUL54_00640
BSAFBSL056_03220
BITBIS30_00395
BACQDOE78_15425(ablB)
BFDNCTC4823_00156
BDAFSZ17_14235(ablB)
BSHILGQ02_09125(ablB)
BCABEFK13_10900(ablB)
BHKB4U37_11910
BCOHBC6307_10970
BMQBMQ_4041
BMDBMD_4026
BMHBMWSH_1183
BMEGBG04_955(ablB)
BEOBEH_06225
BFXBC359_07875
PKSIE339_06905(ablB)
BHABH2257
BKWBkAM31D_12435(yodP)
BGIBGM20_04460
BPFBpOF4_18620
BONA361_18675
BKOCKF48_19595(ablB)
CGOTJ1899_13470(ablB)
ANMGFC28_580(ablB)
AAMYGFC30_1858(ablB)
ANLGFC29_1044(ablB)
ANDGRQ40_09905(ablB)
ACAIISX45_07260(ablB)
ASEDIRT44_12700(ablB)
HHDHBHAL_3877
HMNHM131_14045
FPNABE65_009370
FARABE41_010655
BSJUP17_14270 UP17_19665
BMURABE28_013265 ABE28_018460
PBUTDTO10_01460(ablB) DTO10_06460(ablB)
PASABAOM_3336
PPSRI6J18_22310(ablB)
GRCGI584_00325(ablB)
NMKCHR53_18210(ablB)
MEKUHUW50_16835(ablB)
MSEMGMB29_08205(ablB)
MDGK8L98_03085(ablB) K8L98_14360(ablB)
AIAAWH56_019870(ablB)
BVQFHE72_13420(ablB)
RMFD5E69_12965(ablB)
GAJMY490_01865(ablB)
BBEBBR47_20910
BLRBRLA_c014500(yodP)
BFMBP422_05595
BAGRBA6348_18640(ablB)
BRWGOP56_00175(ablB)
BCHSJNE38_11025(ablB)
BCOPJD108_14080(ablB)
PALBEJC50_16270(ablB)
ANXACH33_16675
ASOCCB4_04199(yodP)
ATHEK3F53_02170(ablB)
COHEAV92_13085(ablB)
TUMCBW65_01280
PANCE2636_15740(ablB)
LFBC1X05_08465(ablB)
TVUAB849_006385(ablB)
CBECbei_1453 Cbei_2936
CBZCbs_1453 Cbs_2936
CBEILF65_01557
CPASClopa_3529 Clopa_3775
CPATCLPA_c13710(ablB)
CPAECPAST_c13710(ablB)
CSQCSCA_2502
CLDCLSPO_c15730(ablB)
CCKCcar_02205
CTYKCTK_C05930
CTAEBGI42_06410(ablB)
CDRKB9W14_07190
CDYF3K33_07525(ablB) F3K33_14930(ablB)
CFERD4Z93_09495(ablB)
CLOSDMR38_14955(ablB) DMR38_19200(ablB)
AMTAmet_3657
HSCHVS_06555(yodP)
CLEClole_3466
EACEAL2_808p00700(yodP)
TEBT8CH_0439(ablB)
SALQSYNTR_1222
DORDesor_2830 Desor_4630
DMIDesmer_3675
DEDDHBDCA_p19
DECDCF50_p80
DRSDEHRE_00260 DEHRE_04865
DRMDred_0739
DRUDesru_0248
DAEDtox_0601
DKUDesku_2595
DAUDaud_0170
DGIDesgi_1712 Desgi_2669
HCVFTV88_2325(ablB) FTV88_2886
AWOAwo_c03840
ALKAJ0B03_04700(ablB)
CBARPATL70BA_2535(ablB) PATL70BA_2912(ablB)
ACAEHYG86_09545(ablB)
NCDACONDI_02810(yodP)
AARAcear_1279
HHLHalha_1628
MALANCTC10135_00980
ACITHPK19_20025(ablB)
RTSCE91St31_26710
PBUL21SP3_01567
PBPSTSP1_01892
PBASSMSP2_01927
ALUSSTSP2_00239
TAERGT409_01115(ablB)
SSMSpirs_3982
SGPSpiGrapes_0096
PSACPSM36_1052
DORIFH5T_13975
DRCG0Q07_15175(ablB)
MCOSGM418_06350(ablB)
ASXCDL62_14110(ablB)
MARMYQ22_05335
MARTBTR34_05575
MARBCJ263_11000(ablB)
CAOCelal_1713
FBEFF125_10005(ablB)
CPCCpar_1398
CPBCphamn1_1651
PVICvib_1365
PLTPlut_1575
PAAPaes_0800
PROCPtc2401_01489
PRSB9H02_07280
PROSCHL67_07370(ablB)
DAPDacet_0866
GTLEP073_02610(ablB)
MMPMMP0862(yodP)
MMQMmarC5_0667
MMXMmarC6_1794
MMZMmarC7_0107
MMDGYY_05005
MMAKMMKA1_09540
MMAOMMOS7_09330
MMADMMJJ_01330(yodP)
MAEMaeo_0241
MVNMevan_1222
MBAMbar_A0671
MBYMSBRM_3253
MBWMSBRW_0332
MBARMSBR2_3215
MACMA_3978
MMAMM_0935
MMJMSMAS_0371
MMACMSMAC_0390
MVCMSVAZ_3255
MLSMSLAZ_0569
METMMSMTP_0454
MEFMSWH1_0411
MEQMSWHS_0421
MSJMSSAC_3713
MSZMSSIH_3249
MSWMSSIT_3320
MHORMSHOH_0462
MBUMbur_0273
MELOJ7W08_04635(ablB)
MMHMmah_1438
MHAZBHR79_06480
MZHMzhil_1042
MPYMpsy_1922
MZIHWN40_12605(ablB)
MRTJKHC33_05755(ablB)
MLAMlab_0344
MEMMemar_0216
MBGBN140_0213
MEMAMMAB1_0139 MMAB1_0278
MCHKMchiMG62_05130(yodP)
MPIMpet_1465
MPDMCP_1918
MEZMtc_0927
RCIRRC392
PSYTDSAG12_02764
 » show all
Reference
1  [PMID:14532061]
  Authors
Pfluger K, Baumann S, Gottschalk G, Lin W, Santos H, Muller V
  Title
Lysine-2,3-aminomutase and beta-lysine acetyltransferase genes of methanogenic archaea are salt induced and are essential for the biosynthesis of Nepsilon-acetyl-beta-lysine and growth at high salinity.
  Journal
Appl Environ Microbiol 69:6047-55 (2003)
DOI:10.1128/AEM.69.10.6047-6055.2003
  Sequence
[mma:MM_0935]
Reference
2  [PMID:21538109]
  Authors
Muller S, Hoffmann T, Santos H, Saum SH, Bremer E, Muller V
  Title
Bacterial abl-like genes: production of the archaeal osmolyte N(epsilon)-acetyl-beta-lysine by homologous overexpression of the yodP-kamA genes in Bacillus subtilis.
  Journal
Appl Microbiol Biotechnol 91:689-97 (2011)
DOI:10.1007/s00253-011-3301-8
  Sequence
[bsu:BSU19700]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.264
IUBMB Enzyme Nomenclature: 2.3.1.264
ExPASy - ENZYME nomenclature database: 2.3.1.264
BRENDA, the Enzyme Database: 2.3.1.264

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