KEGG ENZYME: 2.3.1.268

ENZYME: 2.3.1.268

Entry

EC 2.3.1.268                Enzyme

Name

ethanol O-acetyltransferase;
eat1 (gene name);
ethanol acetyltransferase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acetyl-CoA:ethanol O-acetyltransferase

Reaction(IUBMB)

ethanol + acetyl-CoA = ethyl acetate + CoA [RN:R11957]

Reaction(KEGG)

R11957

Substrate

ethanol [CPD:C00469];
acetyl-CoA [CPD:C00024]

Product

ethyl acetate [CPD:C00849];
CoA [CPD:C00010]

Comment

The enzyme, characterized from the yeast Wickerhamomyces anomalus, is responsible for most ethyl acetate synthesis in known ethyl acetate-producing yeasts. It is only distantly related to enzymes classified as EC 2.3.1.84, alcohol O-acetyltransferase. The enzyme also possesses thioesterase and esterase activities, which are inhibited by high ethanol concentrations.

History

EC 2.3.1.268 created 2018

Orthology

K22586

ethanol O-acetyltransferase

Reference

1 [PMID:28356220]

Authors

Kruis AJ, Levisson M, Mars AE, van der Ploeg M, Garces Daza F, Ellena V, Kengen SWM, van der Oost J, Weusthuis RA

Title

Ethyl acetate production by the elusive alcohol acetyltransferase from yeast.

Journal