Entry
Name
lyso-ornithine lipid O-acyltransferase;
olsA (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
Nalpha-[(3R)-hydroxy-acyl]-L-ornithine O-acyltransferase
Reaction(IUBMB)
a lyso-ornithine lipid + an acyl-[acyl-carrier protein] = an ornithine lipid + a holo-[acyl-carrier protein] [RN:
R12086 ]
Reaction(KEGG)
Substrate
lyso-ornithine lipid [CPD:
C21680 ];
acyl-[acyl-carrier protein] [CPD:
C00173 ]
Product
ornithine lipid [CPD:
C21672 ];
holo-[acyl-carrier protein] [CPD:
C00229 ]
Comment
This bacterial enzyme catalyses the second step in the formation of ornithine lipids.
History
EC 2.3.1.270 created 2018
Orthology
K22617 lyso-ornithine lipid O-acyltransferase
Genes
PRW : PsycPRwf_1866 PsycPRwf_1867
PSYC : DABAL43B_0457(plsC)
PSYY : DLE54_08775 DLE54_08780
PRAE : MN210_12880 MN210_12885
MCUN : NCTC10297_00947(plsC)
TNI : TVNIR_1081(plsC_[H])
ATY : A9R16_004535 A9R16_008325
RBS : RHODOSMS8_03202(plsC)
SMEL : SM2011_c01116(olsA)
SAME : SAMCFNEI73_Ch0414(plsC)
AGR : AGROH133_03543(plsC)
AVV : RvVAT039_20080(olsA)
AVF : RvVAR031_07230(olsA)
REC : RHECIAT_CH0000417(olsA)
RTR : RTCIAT899_CH02410(olsA)
NEN : NCHU2750_00400(plsC)
MAQU : Maq22A_1p32115(plsC)
MIWA : SS37A_16440(plsC_1)
MECQ : MSC49_25930(plsC_2)
PLEO : OHA_1_03367(plsC_2)
NOR : FA702_05990 FA702_09500
SSAN : NX02_13925 NX02_23660
SLAA : EUU25_02320 EUU25_03130
PALG : HFP57_09105 HFP57_09110
ABG : Asbog_01652 Asbog_02756
KBA : A0U89_04505 A0U89_13565
NCH : A0U93_04030 A0U93_13925
KDP : N5W20_04065 N5W20_07935
TII : DY252_01130 DY252_11780
THAI : IT893_09460 IT893_19610
TTB : MACH01_18840 MACH01_38300
PAQI : KW060_02905 KW060_11225
PBAP : Pla133_06510 Pla133_29290
GEP : Q9293_08615 Q9293_08660
» show all
Taxonomy
Reference
Authors
Weissenmayer B, Gao JL, Lopez-Lara IM, Geiger O
Title
Identification of a gene required for the biosynthesis of ornithine-derived lipids.
Journal
Sequence
Reference
Authors
Aygun-Sunar S, Bilaloglu R, Goldfine H, Daldal F
Title
Rhodobacter capsulatus OlsA is a bifunctional enzyme active in both ornithine lipid and phosphatidic acid biosynthesis.
Journal
Reference
Authors
Lewenza S, Falsafi R, Bains M, Rohs P, Stupak J, Sprott GD, Hancock RE
Title
The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.3.1.270