KEGG   ENZYME: 2.3.1.272
Entry
EC 2.3.1.272                Enzyme                                 

Name
2-acetylphloroglucinol acetyltransferase;
MAPG ATase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
2-acetylphloroglucinol C-acetyltransferase
Reaction(IUBMB)
2 2-acetylphloroglucinol = 2,4-diacetylphloroglucinol + phloroglucinol [RN:R12087]
Reaction(KEGG)
R12087
Substrate
2-acetylphloroglucinol [CPD:C21895]
Product
2,4-diacetylphloroglucinol [CPD:C21896];
phloroglucinol [CPD:C02183]
Comment
The enzyme from the bacterium Pseudomonas sp. YGJ3 is composed of three subunits named PhlA, PhlB and PhlC. Production of 2,4-diacetylphloroglucinol, which has antibiotic activity, is strongly inhibited by chloride ions.
History
EC 2.3.1.272 created 2018
Orthology
K22838  2-acetylphloroglucinol acetyltransferase
K22839  2-acetylphloroglucinol acetyltransferase
K22840  2-acetylphloroglucinol acetyltransferase
Genes
PFL: PFL_5954(phlA) PFL_5955(phlC) PFL_5956(phlB)
PPRC: PFLCHA0_c59080 PFLCHA0_c59090 PFLCHA0_c59100
PPRO: PPC_5901(phlA) PPC_5902(phlC) PPC_5903(phlB)
PFE: PSF113_2460(phlB) PSF113_2461(phlC) PSF113_2462(phlA)
PBA: PSEBR_a2320 PSEBR_a2321 PSEBR_a2322
PSOS: POS17_5896(phlA) POS17_5897(phlC) POS17_5898(phlB)
POJ: PtoMrB4_28160 PtoMrB4_28170 PtoMrB4_28180
PBZ: GN234_00505 GN234_00510 GN234_00515
CVC: BKX93_21160 BKX93_21165 BKX93_21170
SMC: SmuNN2025_1776 SmuNN2025_1777 SmuNN2025_1778
 » show all
Reference
1  [PMID:22451400]
  Authors
Hayashi A, Saitou H, Mori T, Matano I, Sugisaki H, Maruyama K
  Title
Molecular and catalytic properties of monoacetylphloroglucinol acetyltransferase from Pseudomonas sp. YGJ3.
  Journal
Biosci Biotechnol Biochem 76:559-66 (2012)
DOI:10.1271/bbb.110860
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.272
IUBMB Enzyme Nomenclature: 2.3.1.272
ExPASy - ENZYME nomenclature database: 2.3.1.272
BRENDA, the Enzyme Database: 2.3.1.272

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