KEGG   ENZYME: 2.3.1.276
Entry
EC 2.3.1.276                Enzyme                                 

Name
galactosamine-1-phosphate N-acetyltransferase;
ST0452 (locus name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:alpha-D-galactosamine-1-phosphate N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + alpha-D-galactosamine 1-phosphate = CoA + N-acetyl-alpha-D-galactosamine 1-phosphate [RN:R12242]
Reaction(KEGG)
R12242
Substrate
acetyl-CoA [CPD:C00024];
alpha-D-galactosamine 1-phosphate [CPD:C22029]
Product
CoA [CPD:C00010];
N-acetyl-alpha-D-galactosamine 1-phosphate [CPD:C18060]
Comment
The enzyme, characterized from the archaeon Sulfolobus tokodaii, is also active toward alpha-D-glucosamine 1-phosphate (cf. EC 2.3.1.157, glucosamine-1-phosphate N-acetyltransferase). In addition, that enzyme contains a second domain that catalyses the activities of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase, EC 2.7.7.24, glucose-1-phosphate thymidylyltransferase, and EC 2.7.7.83, UDP-N-acetylgalactosamine diphosphorylase.
History
EC 2.3.1.276 created 2018
Orthology
K23144  UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase
Genes
EOI: ECO111_0395
EOH: ECO103_0341
ECK: EC55989_0369(yaiX)
ECP: ECP_2000
ECR: ECIAI1_0361(yaiX)
ECQ: ECED1_0389(yaiX)
EUM: ECUMN_0402(yaiX)
ECT: ECIAI39_0319(yaiX)
EOC: CE10_0327(yaiX1)
ECZ: ECS88_0359(yaiX)
ELC: i14_0450
ELD: i02_0450
SSN: SSON_0338
PSUW: WQ53_10435
PPUT: L483_02960
PFB: VO64_5260
PANR: A7J50_2687
MMAI: sS8_0793
TIG: THII_0760
GAI: IMCC3135_05880(gtaB_1)
PLG: NCTC10937_02284(glmU_1)
HYF: DTO96_100664(glmU_2)
CJS: CJS3_1512
CJR: CJE1604
CCOI: YSU_01825
CCOF: VC76_07075
CIS: CINS_0298
AMOL: AMOL_0796
DPS: DP2923
DSF: UWK_00375
DOL: Dole_0521
DBR: Deba_1437
MHUA: MCHK_12705
MAQU: Maq22A_c21040(wbbJ)
PSF: PSE_2179
SHUM: STHU_14300
BHA: BH3324
BCL: ABC0490
CLS: CXIVA_24110(WbbJ)
CCE: Ccel_0970
RUM: CK1_17920
BPB: bpr_I1661
BFI: CIY_16790
BHU: bhn_I1100
RIX: RO1_13020
RIM: ROI_24530
COO: CCU_29180
CCT: CC1_33860
ROB: CK5_23860
BPRO: PMF13cell1_04569(glmU_2)
CPY: Cphy_3271
CSCI: HDCHBGLK_03222(glmU_1)
CSO: CLS_27920
BPRL: CL2_11950
HSD: SD1D_0594
EHL: EHLA_1657
RTO: RTO_26990
ERT: EUR_17270
ERA: ERE_31610
BPRS: CK3_28050
EUC: EC1_02740
STRM: M444_37390
SLAU: SLA_2433
ACIJ: JS278_00868(hddC)
KAL: KALB_2025
DET: DET0530
DEH: cbdbA500
DMC: btf_492(glmU1) btf_493(glmU2)
DMD: dcmb_538(glmU1) dcmb_539(glmU2)
DMG: GY50_0455(rfbA) GY50_0456(rfbA)
RCA: Rcas_3684
CAG: Cagg_2516
HAU: Haur_4116
TRA: Trad_0038
CTD: CTDEC_0629(glmU)
CTF: CTDLC_0629(glmU)
CTY: CTR_6331(glmU)
CRA: CTO_0682
CTRQ: A363_00674
CTB: CTL0893(glmU)
CTL: CTLon_0887(glmU)
CTO: CTL2C_500
CTJ: JALI_6331(glmU)
CTZ: CTB_6331(glmU)
CSW: SW2_6401(glmU)
CES: ESW3_6401(glmU)
CTRB: BOUR_00669
CTEC: EC599_6511(glmU)
CFS: FSW4_6401(glmU)
CFW: FSW5_6401(glmU)
CTFW: SWFP_6781(glmU)
CTCH: O173_03455
CTRI: BN197_6381(glmU)
CTRA: BN442_6381(glmU)
CTCT: CTW3_03465
CMUR: Y015_04880
CMX: DNC_04675
CMZ: TAC_04880
CPJ: glmU(glmU)
CPM: G5S_0292(grad)
CPEC: CPE3_0965(glmU)
CPEO: CPE1_0964(glmU)
CPER: CPE2_0965(glmU)
CHB: G5O_1060
CHR: Cpsi_9941
CPSC: B711_1153
CPSN: B712_1081
CPSB: B595_1155
CPSG: B598_1079
CPSM: B602_1083
CPSI: B599_1077
CPSV: B600_1150
CPSW: B603_1087
CPST: B601_1085
CPSD: BN356_9981
CPSA: AO9_05180
CAV: M832_07950(yaiX)
CABO: AB7_10761
CHLA: C834K_1038(glmU)
CSUI: Chls_982(glucosamine-1-phosphate_N-acetyltransferase)
PNL: PNK_0001(glmu1)
PUV: PUV_00040
WCH: wcw_0013(glmU1)
OTE: Oter_2108
OBG: Verru16b_02411(glmU)
CAA: Caka_1053
AGL: PYTT_1213
XII: AMD24_00564(glmU)
MIN: Minf_1116(gcd1) Minf_1422(gcd1)
RBA: RB4043
PSL: Psta_0489
RUL: UC8_17770(glmU_2)
MFF: MFFC18_50350(glmU_2)
ROL: CA51_48400(glmU_2)
AHEL: Q31a_04470(glmU_1)
LCRE: Pla8534_55990(glmU_2)
BVO: Pan97_14530(glmU_2)
TTF: THTE_3077
PLM: Plim_0653
PLS: VT03_02750(glmU_1) VT03_08990
GES: VT84_32030(hddC_4) VT84_35885
IPA: Isop_0466
SACI: Sinac_3268
KST: KSMBR1_0659(rfbA_2)
PCOR: KS4_37140(lpxD_2)
PBU: L21SP3_00674(glmU)
PBP: STSP1_00283(glmU)
LBI: LEPBI_II0119(galU2)
LBF: LBF_4116
SRU: SRU_1939
SRM: SRM_02154
LBY: Lbys_3028
ZPR: ZPR_2553
MLT: VC82_2196
AALG: AREALGSMS7_01811(glmU)
EAO: BD94_3322
BMM: MADAR_499
BBG: BGIGA_513
BLP: BPAA_521
BLU: K645_566
IAL: IALB_0376
MRO: MROS_2499
DTU: Dtur_1633
CTHI: THC_1077
MJA: MJ_1101
MMP: MMP1076
MMD: GYY_06215
MMAD: MMJJ_17730(glmU)
MAE: Maeo_0642
MVO: Mvol_0247
MTH: MTH_1589
METC: MTCT_1448
MWO: MWSIV6_0133(glmU)
METE: tca_01538(glmU_3)
MST: Msp_1301
MRU: mru_0456(glmU)
MSI: Msm_0655
MEB: Abm4_0226(glmU)
MMIL: sm9_0316(glmU)
MEYE: TL18_01350
MOL: YLM1_0128
METH: MBMB1_0406(glmU)
MFC: BRM9_1856(glmU)
MCUB: MCBB_0372
MFV: Mfer_0129
MKA: MK0892
PFU: PF0235
PFI: PFC_00225
PHO: PH1925(PH1925)
PAB: PAB1115(graD-2)
PYN: PNA2_0881
PYS: Py04_0389
TKO: TK1188
TON: TON_0359
TGA: TGAM_0642
TSI: TSIB_1312
THE: GQS_03435
THA: TAM4_697
THM: CL1_0291
TLT: OCC_08739
THS: TES1_0783
TNU: BD01_0352
TEU: TEU_07655
PPAC: PAP_06275
MAC: MA_3025(rfbA)
MBU: Mbur_2341(glmU) Mbur_2344
MHI: Mhar_2268
MHU: Mhun_2853
MLA: Mlab_0666
MBG: BN140_1430(glmU1) BN140_1431(glmU2)
MEMA: MMAB1_1835 MMAB1_1836(rfbA)
MPI: Mpet_1015
MEZ: Mtc_0552(glmU-1) Mtc_2010(glmU-2) Mtc_2013(glmU-3)
RCI: RCIX1434(rfbA-3) RCIX1438(rfbA-4)
HAL: VNG_0009G(graD2)
HSL: OE_1014R(graD5) OE_1016R(graD2)
HALH: HTSR_0883 HTSR_0890(glmU)
HHSR: HSR6_0623(glmU) HSR6_0898(graD2) HSR6_0906(glmU2)
HSU: HLASF_0888(graD1) HLASF_0890(glmU) HLASF_0902(graD3) HLASF_1529(graD4)
HSF: HLASA_0885(graD1) HLASA_0887(glmU) HLASA_0899(graD3) HLASA_1516(graD4)
HMA: rrnAC1081(rffH1)
HHI: HAH_0485(graD4c) HAH_0488(rffH1) HAH_1684(rffH2)
NPH: NP_2386A(graD5) NP_4276A(graD6) NP_4652A(graD1) NP_4656A(graD2)
NMO: Nmlp_3551(aglF)
HALL: LC1Hm_0675(gcd1) LC1Hm_1393
HWA: HQ_2989A(graD3) HQ_2992A(graD4)
HWC: Hqrw_3398(graD5) Hqrw_3399(aglF2) Hqrw_3501(graD3) Hqrw_3506(graD4)
HVO: HVO_A0586(graD3)
HME: HFX_2130(rffH1) HFX_2144(graD5) HFX_6127(rffH1) HFX_6304(graD4C) HFX_6312(rffH1)
HDF: AArcSl_0144(rfbA) AArcSl_1488(rfbA3) AArcSl_1933(glmU) AArcSl_2816(rfbA4)
NMG: Nmag_0920(graD1) Nmag_0979(graD5) Nmag_3048(graD2)
FAI: FAD_1373
ACJ: ACAM_0762
SMR: Smar_0849
IHO: Igni_0873
DKA: DKAM_1334
TAG: Tagg_1347
IAG: Igag_1093
HBU: Hbut_1036
STO: STK_04520
SSO: SSO0745
SOL: Ssol_1801
SSOA: SULA_1827
SSOL: SULB_1828
SSOF: SULC_1826
SAI: Saci_0619
SID: M164_1391
SII: LD85_1602
SIH: SiH_1343
SIR: SiRe_1265
SIC: SiL_1256
MSE: Msed_0068
MCN: Mcup_1988
AHO: Ahos_0822
STEP: IC006_1737
PIS: Pisl_0619
PCL: Pcal_1692
PAS: Pars_1564
POG: Pogu_0650
TNE: Tneu_1502
CMA: Cmaq_1548
TTN: TTX_1421(snt-4)
TUZ: TUZN_2122
VDI: Vdis_0926
ASC: ASAC_1091
ACIA: SE86_06590
NEV: NTE_02042
NDV: NDEV_1476
CCAI: NAS2_0547
BARC: AOA65_1819(glmU_2)
BARB: AOA66_1497(glmU_3)
LOKI: Lokiarch_02940(glmU_1) Lokiarch_26580(glmU_5) Lokiarch_45000(aglF)
PSYT: DSAG12_02719(glmU_4)
 » show all
Reference
1  [PMID:15598657]
  Authors
Zhang Z, Tsujimura M, Akutsu J, Sasaki M, Tajima H, Kawarabayasi Y
  Title
Identification of an extremely thermostable enzyme with dual sugar-1-phosphate nucleotidylyltransferase activities from an acidothermophilic archaeon, Sulfolobus tokodaii strain 7.
  Journal
J Biol Chem 280:9698-705 (2005)
DOI:10.1074/jbc.M411211200
Reference
2  [PMID:20400541]
  Authors
Zhang Z, Akutsu J, Kawarabayasi Y
  Title
Identification of novel acetyltransferase activity on the thermostable protein ST0452 from Sulfolobus tokodaii strain 7.
  Journal
J Bacteriol 192:3287-93 (2010)
DOI:10.1128/JB.01683-09
  Sequence
[sto:STK_04520]
Reference
3  [PMID:29507091]
  Authors
Dadashipour M, Iwamoto M, Hossain MM, Akutsu JI, Zhang Z, Kawarabayasi Y
  Title
Identification of a Direct Biosynthetic Pathway for UDP-N-Acetylgalactosamine from Glucosamine-6-Phosphate in Thermophilic Crenarchaeon Sulfolobus tokodaii.
  Journal
J Bacteriol 200:e00048-18 (2018)
DOI:10.1128/JB.00048-18
  Sequence
[sto:STK_04520]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.276
IUBMB Enzyme Nomenclature: 2.3.1.276
ExPASy - ENZYME nomenclature database: 2.3.1.276
BRENDA, the Enzyme Database: 2.3.1.276

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