KEGG   ENZYME: 2.3.1.316
Entry
EC 2.3.1.316                Enzyme                                 
Name
N-hydroxyputrescine acetyltransferase;
fbsK (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:N-hydroxyputrescine N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + N-hydroxyputrescine = N1-acetyl-N1-hydroxyputrescine + CoA [RN:R13301]
Reaction(KEGG)
R13301
Substrate
acetyl-CoA [CPD:C00024];
N-hydroxyputrescine [CPD:C22888]
Product
N1-acetyl-N1-hydroxyputrescine [CPD:C22902];
CoA [CPD:C00010]
Comment
The enzyme, characterized from the bacterium Acinetobacter baumannii ATCC 17978, participates in the biosynthesis of fimsbactin siderophores.
History
EC 2.3.1.316 created 2024
Orthology
K27489  N-hydroxyputrescine acetyltransferase
Genes
ACB: A1S_2570
ACI: ACIAD2767
ASOL: BEN76_08840
Reference
1  [PMID:23456955]
  Authors
Proschak A, Lubuta P, Grun P, Lohr F, Wilharm G, De Berardinis V, Bode HB.
  Title
Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi.
  Journal
Chembiochem 14:633-8 (2013)
DOI:10.1002/cbic.201200764
  Sequence
[aci:ACIAD2767] [acb:A1S_2570]
Reference
2  [PMID:36122366]
  Authors
Yang J, Wencewicz TA.
  Title
In Vitro Reconstitution of Fimsbactin Biosynthesis from Acinetobacter baumannii.
  Journal
ACS Chem Biol 17:2923-2935 (2022)
DOI:10.1021/acschembio.2c00573
  Sequence
[acb:A1S_2570]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.316
IUBMB Enzyme Nomenclature: 2.3.1.316
ExPASy - ENZYME nomenclature database: 2.3.1.316
BRENDA, the Enzyme Database: 2.3.1.316

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (3)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (13)   

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