KEGG   ENZYME: 2.3.1.327
Entry
EC 2.3.1.327                Enzyme                                 
Name
long-chain acyl-[acp]:L-phenylalanine N-acyltransferase;
N-acyl amino acid synthase A;
nasA (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
long-chain acyl-[acp]:L-phenylalanine N-acyltransferase
Reaction(IUBMB)
11-methyldodecanoyl-[acp] + L-phenylalanine = [acp] + N-(11-methyldodecanoyl)-L-phenylalanine [RN:R13432]
Reaction(KEGG)
R13432
Substrate
11-methyldodecanoyl-[acp] [CPD:C22992];
L-phenylalanine [CPD:C00079]
Product
acp [CPD:C00229];
N-(11-methyldodecanoyl)-L-phenylalanine [CPD:C22993]
Comment
The enzyme, characterized from an environmental DNA sample and expressed in Paraburkholderia graminis, catalyses the transfer of linear and branched long-chain acyl-[acp] molecules to L-phenylalanine, forming N-acyl-L-phenylalanine molecules.
History
EC 2.3.1.327 created 2024
Orthology
K27985  long-chain acyl-[acp]:L-phenylalanine N-acyltransferase
Reference
1  [PMID:20081001]
  Authors
Craig JW, Chang FY, Kim JH, Obiajulu SC, Brady SF.
  Title
Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria.
  Journal
Appl Environ Microbiol 76:1633-41 (2010)
DOI:10.1128/AEM.02169-09
  Sequence
[ag:ACX33946]
Reference
2  [PMID:21714057]
  Authors
Craig JW, Brady SF.
  Title
Discovery of a metagenome-derived enzyme that produces branched-chain acyl-(acyl-carrier-protein)s from branched-chain alpha-keto acids.
  Journal
Chembiochem 12:1849-53 (2011)
DOI:10.1002/cbic.201100215
  Sequence
[ag:ACX33946]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.327
IUBMB Enzyme Nomenclature: 2.3.1.327
ExPASy - ENZYME nomenclature database: 2.3.1.327
BRENDA, the Enzyme Database: 2.3.1.327

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (7)   

Download RDF
DBGET integrated database retrieval system