KEGG   ENZYME: 2.3.1.45
Entry
EC 2.3.1.45                 Enzyme                                 
Name
N-acetylneuraminate 7-O(or 9-O)-acetyltransferase;
N-acetylneuraminate 7(8)-O-acetyltransferase;
sialate O-acetyltransferase;
N-acetylneuraminate 7,8-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase;
glycoprotein 7(9)-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase;
N-acetylneuraminate O7-(or O9-)acetyltransferase;
acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O(or 9-O)-acetylneuraminate [RN:R01807 R01808]
Reaction(KEGG)
R01807 R01808
Substrate
acetyl-CoA [CPD:C00024];
N-acetylneuraminate [CPD:C00270]
Product
CoA [CPD:C00010];
N-acetyl-7-O-acetylneuraminate [CPD:C04016];
N-acetyl-9-O-acetylneuraminate [CPD:C04017]
Comment
Both free and glycosidically bound N-acetyl- and N-glycolylneuraminates can act as O-acetyl acceptors.
History
EC 2.3.1.45 created 1972
Orthology
K03377  N-acetylneuraminate 9-O-acetyltransferase
Genes
HSA64921(CASD1)
PTR463543(CASD1)
PPS100974499(CASD1)
GGO101143379(CASD1)
PON100438741(CASD1)
NLE100598487(CASD1)
MCC700222(CASD1)
MCF101867425(CASD1)
CSAB103226535(CASD1)
CATY105592187(CASD1)
PANU101010684(CASD1)
TGE112621401(CASD1)
RRO104682782(CASD1)
RBB108517183(CASD1)
TFN117073709(CASD1)
PTEH111552423(CASD1)
CJC100411081(CASD1)
SBQ101031614(CASD1)
CSYR103271378(CASD1)
MMUR105867285(CASD1)
LCAT123647130(CASD1)
OGA100961273(CASD1)
MMU213819(Casd1)
MCAL110296519(Casd1)
MPAH110315189(Casd1)
RNO678772(Casd1)
MCOC116098545(Casd1)
MUN110556869(Casd1)
CGE100766850(Casd1)
MAUA101826918(Casd1)
PLEU114693445(Casd1)
MORG121463414(Casd1)
NGI103725223(Casd1)
HGL101722739(Casd1)
CPOC100719716(Casd1)
CCAN109701308(Casd1)
DORD106000588(Casd1)
DSP122111897(Casd1)
NCAR124991674
OCU100352588(CASD1)
OPI101532604(CASD1)
TUP102497173(CASD1)
CFA475232(CASD1)
VVP112923898(CASD1)
VLG121474809(CASD1)
AML100476885(CASD1)
UMR103658798(CASD1)
UAH113260112(CASD1)
UAR123789275(CASD1)
ELK111147385
LLV125081240
MPUF101690054(CASD1)
ORO101374359(CASD1)
EJU114220778(CASD1)
ZCA113910931(CASD1)
MLX118020777(CASD1)
FCA101094006(CASD1)
PYU121028726(CASD1)
PBG122487892(CASD1)
PTG102966512(CASD1)
PPAD109263703(CASD1)
AJU106969952(CASD1)
HHV120234439(CASD1)
BTA532541(CASD1)
BOM102268785(CASD1)
BIU109558216(CASD1)
BBUB102415332(CASD1)
CHX102186927(CASD1)
OAS101114863(CASD1)
ODA120877958(CASD1)
CCAD122438103(CASD1)
SSC100521674(CASD1)
CFR102522624(CASD1)
CBAI105082888(CASD1)
CDK105088731(CASD1)
VPC102544781(CASD1)
BACU103006473(CASD1)
LVE103069901(CASD1)
OOR101289219(CASD1)
DLE111181093(CASD1)
PCAD102973895(CASD1)
PSIU116759586(CASD1)
ECB100062437(CASD1)
EPZ103553630(CASD1)
EAI106838932(CASD1)
MYB102252428(CASD1)
MYD102761672(CASD1)
MMYO118666212(CASD1)
MLF102434672(CASD1)
MNA107541703(CASD1)
PKL118714284(CASD1)
HAI109371941(CASD1)
DRO112319800(CASD1)
SHON118987349(CASD1)
AJM119047355(CASD1)
PDIC114507530(CASD1)
PHAS123811667(CASD1)
MMF118619982(CASD1)
RFQ117012331(CASD1)
PALE102880254(CASD1)
PGIG120615010(CASD1)
PVP105294347(CASD1)
RAY107518818(CASD1)
MJV108398406(CASD1)
TOD119242316(CASD1)
SARA101550557(CASD1)
LAV100676405(CASD1)
TMU101340759
DNM101438677(CASD1)
MDO100032269(CASD1)
GAS123250663(CASD1)
SHR100916306(CASD1)
PCW110217578(CASD1)
OAA114813791(CASD1)
GGA420565(CASD1)
PCOC116243290(CASD1)
MGP100540591
CJO107309084(CASD1)
NMEL110393370(CASD1)
APLA101800215(CASD1)
ACYG106039663(CASD1)
AFUL116485925(CASD1)
TGU100222894(CASD1)
LSR110474733(CASD1)
SCAN103812825(CASD1)
PMOA120502287(CASD1)
OTC121338114(CASD1)
PRUF121353031(CASD1)
GFR102033654(CASD1)
FAB101810789(CASD1)
PHI102100408(CASD1)
PMAJ107199998(CASD1)
CCAE111924230(CASD1)
CCW104689166(CASD1)
ETL114072803(CASD1)
ZAB102067351(CASD1)
FPG101921816(CASD1)
FCH102046861(CASD1)
CLV102090215(CASD1)
EGZ104129019(CASD1)
NNI104014015(CASD1)
PLET104627784(CASD1)
ACUN113477353(CASD1)
TALA104364759(CASD1)
PADL103922377(CASD1)
ACHC115338827(CASD1)
AAM106483396(CASD1)
AROW112976478(CASD1)
NPD112951095(CASD1)
DNE112982332(CASD1)
ASN102372728(CASD1)
AMJ102569055(CASD1)
CPOO109308925(CASD1)
GGN109291420(CASD1)
PSS102457331(CASD1)
CMY102939537(CASD1)
CPIC101934247(CASD1)
TST117872225(CASD1)
CABI116827642(CASD1)
MRV120398274(CASD1)
ACS100560188(casd1)
PVT110074747(CASD1)
SUND121934081(CASD1)
PBI103053522(CASD1)
PMUR107283646(CASD1)
TSR106541911(CASD1)
PGUT117655147(CASD1)
VKO123022792(CASD1)
PMUA114607613(CASD1)
ZVI118091719(CASD1)
GJA107117998(CASD1)
STOW125441077(CASD1)
XLA108718841(casd1.L) 108719904(casd1.S)
XTR100216199(casd1)
NPR108790505(CASD1)
RTEM120939896(CASD1)
BBUF121000640(CASD1)
BGAR122937810(CASD1)
DRE692268(casd1)
SRX107722141 107731667
SANH107665666 107669810
SGH107591593 107593528(casd1)
CCAR109063401(casd1) 109103049
CAUA113062053 113119366
PPRM120485450(casd1)
MAMB125274982(casd1)
IPU108257082(casd1)
PHYP113535978(casd1)
SMEO124376293(casd1)
TFD113661554(casd1)
AMEX103024597(casd1)
EEE113578671(casd1)
TRU101070985(casd1)
TNGGSTEN00002709G001
LCO104922871(casd1)
NCC104961900(casd1)
CGOB115015494(casd1)
ELY117263521(casd1)
PLEP121957643(casd1)
SLUC116066902(casd1)
ECRA117956922(casd1)
PFLV114568350(casd1)
GAT120826561(casd1)
PPUG119219297(casd1)
MSAM119906987(casd1)
CUD121524094(casd1)
ALAT119015514(casd1)
MZE101485804(casd1)
ONL100691579(casd1)
OAU116319470(casd1)
OLA101169373(casd1)
OML112162995(casd1)
XMA102231942(casd1)
XCO114156270(casd1)
XHE116731483(casd1)
PRET103472237(casd1)
PFOR103152517(casd1)
PLAI106952334(casd1)
PMEI106923964(casd1)
GAF122843265(casd1)
CVG107085873(casd1)
CTUL119785867(casd1)
GMU124879161(casd1)
NFU107383296(casd1)
KMR108239299(casd1)
ALIM106519534(casd1)
NWH119425725(casd1)
AOCE111583719(casd1)
CSEM103394117(casd1)
POV109631756(casd1)
SSEN122786368(casd1)
HHIP117770895(casd1)
HSP118124505(casd1)
LCF108876906(casd1)
SDU111223046(casd1)
SLAL111656927(casd1)
XGL120786118(casd1)
HCQ109527681(casd1)
BPEC110153169 110153991 110171387 110174112 110174113
MALB109968109(casd1)
BSPL114865739(casd1)
SASA106570464 106588938(casd1)
OTW112229483 112264352
OMY110488018 110496631(casd1)
OGO124012596 124043249
ONE115119902 115131314
SALP111955427 112068426
SNH120022141 120026913
ELS105022786(casd1)
SFM108922005(casd1)
PKI111843905(casd1)
AANG118233939(casd1)
LOC102689127(casd1)
PSPA121313555 121315032
ARUT117394176(casd1) 117400447
LCM102345636(CASD1)
CMK103189016(casd1)
RTP109931283(casd1)
BFO118404490 118404773 118405701
BBEL109465441 109479493 109479494
CIN100177911
SCLV120328015
SPU100889298 589726
APLC110978315 110990869
SKO100367230 102801776
DMEDmel_CG2938(CG2938)
DER6550885
DSE6612552
DSIDsimw501_GD16317(Dsim_GD16317)
DYADyak_GE16879
DAN6503783
DSR110184604
DPODpse_GA15532
DPE6597592
DMN108159038
DWI6638069
DGR6569186
DMODmoj_GI16046
DAZ108620045
DNV108657187
DHE111593427
DVI6634721
CCAT101453844
BOD106618714
MDE101896007
SCAC106086977
LCQ111687436
LSQ119604825
HIS119657447
AGAAgaP_AGAP001402
ACOZ120952158
AARA120897827
ASTE118506471
AAG5565042
AALB109405957 115266519
CQUCpipJ_CPIJ003344
CPII120425466
CNS116341932
BCOO119067830
AME411555
ACER108001831
ALAB122716739
BIM100747938
BBIF117209128
BVK117233892
BVAN117160760
BTER100648596
BPYO122569424
CCAL108632394
OBB114871184
MGEN117228883
NMEA116424225
CGIG122395057
SOC105198766
MPHA105839945
AEC105148741
ACEP105618612
PBAR105422067
VEM105569087
HST105191814
DQU106750961
CFO105251781
FEX115244871
LHU105675610
PGC109854082
OBO105275185
PCF106788211
PFUC122517760
VPS122634500
MDL103580488
CGLO123264612
FAS105272670
DAM107035517
AGIF122850242
CCIN107267068
TCA655926
DPA109536156
SOY115887360
ATD109596748
CSET123315878
AGB108908202
LDC111503851
NVL108563604
APLN108737082
PPYR116181062
OTU111414368
BMOR101738522
BMAN114242216
MSEX115449560
DPLKGM_210375
BANY112051353
PMAC106709137
PXU106121496
PRAP111003476
ZCE119828302
HAW110380934
TNL113498029
SLIU111359027
OFU114350861
PXY105385315 105396705
API100160184
DNX107166606 107172675
AGS114125410
RMD113560690
BTAB109039562
DCI103515762
CLEC106667427
HHAL106686569
NLU111047738 120351630
PHUPhum_PHUM205440
FOC113203765
TPAL117650690
ZNE110831637
CSEC111874782
FCD110851952
DPXDAPPUDRAFT_112080 DAPPUDRAFT_330622 DAPPUDRAFT_48914
DMK116921559
PVM113804556
PJA122267939
PCHN125047157
HAME121853637 121857620 121874791
PCLA123762114 123766890 123773610
PTRU123503038 123514903 123515112 123515114 123516093
HAZT108665290
EAF111706689
PPOI119091017
ISCIscW_ISCW021640
DSV119456201
RSAN119379495 119383519
RMP119175626
VDE111254785
VJA111268862
TUT107364854
DPTE113790830
DFR124496650
CSCU111616063 111624874
PTEP107436980
SDM118192326
HROHELRODRAFT_89851
LGILOTGIDRAFT_180023 LOTGIDRAFT_63982
PCAN112561411 112572535
BGT106078042
GAE121376901 121387627
HRF124112296 124148515
HRJ124256312 124258728
CRG105319248
MYI110461094
PMAX117317395
MMER123538121 123540969
OBI106868097
OSN115223013
LAK106153362 106165798 106179615
SMMSmp_157560
OVIT265_04091 T265_04747 T265_13408
EGLEGR_01772
NVE5509630 5514202 5521358
EPA110234291 110234783 110234784 110248915
ATEN116288719 116295492 116305786
ADF107334174 107334211 107345509 107346916
AMIL114958250 114968014 114972240
PDAM113676799 113678173 113684346
SPIS111332105 111334033 111335710
DGT114518527 114525664
XEN124444661 124453455
HMG100207689 100209243 101234927
AQU109588945
ATHAT1G29890(RWA4) AT2G34410(RWA3) AT3G06550(RWA2) AT5G46340(RWA1)
ALY9299483 9315564 9320657 9329649
CRB17875446 17888082 17891108
CSAT104724746 104744825 104763061 104764349 104772900 104781829 104786122 104792196
EUSEUTSA_v10000847mg EUTSA_v10016486mg EUTSA_v10020460mg
BRP103827737 103849876 103857534 103865335 103870737
BNA106346085 106346086 106352885 106401717 106402059 106405646 106410799 106432784 106437821 106452994 111198410
BOE106301625 106328582 106334752 106341685 106343472
RSZ108812424 108847969 108848011 108854432 108857151
THJ104806119 104814284 104818874 104820639
CPAP110819772 110824470
CIT102609242 102627793
CICCICLE_v10004685mg CICLE_v10014824mg
PVY116110909 116143250
MINC123193761 123219584 123221726
TCC18596552 18603697
GRA105769404 105773829 105777227 105781621 105788310 105797619
GHI107890014 107896405 107905864 107916221 107960252 121229385 121230869
GAB108453689 108454094 108461000 108489526
DZI111278100 111280042 111280934 111306947
EGR104434093 104440819
GMX100787763 100794337 100808555 100817430
GSJ114393735 114412652 114419942 114421463
PVUPHAVU_002G197200g PHAVU_003G117800g
VRA106752821 106768931
VAR108319406 108321783
VUN114178378 114179119
CCAJ109811002 109813218
APRC113846572 113857403
MTRMTR_4g094590 MTR_4g122920
CAM101493129 101496987
LJALj4g3v0281140.2(Lj4g3v0281140.2) Lj4g3v0281140.3(Lj4g3v0281140.3) Lj4g3v2253590.1(Lj4g3v2253590.1) Lj4g3v2253590.2(Lj4g3v2253590.2)
ADU107462672 107481698
AIP107631558 107639403
AHF112703000 112723197 112734555 112792343
LANG109330139 109350977 109362826
FVE101299564 101312031
RCN112200135 112202879
PPER18780982 18789910
PMUM103323215 103325014
PAVI110752075 110766620
PDUL117622749 117625964
MDM103403516 103434974 103446209 103452661
PXB103945048 103951249 103961277
ZJU107404588 107405302 107413698
MNT21388066 21393919
CSV101207939 101212512 101215014 116405538
CMO103484388 103487174 103487648 103497777
BHJ120068241 120074616 120083773 120090902
MCHA111009596 111010951 111012417
CMAX111478893 111490405 111494498 111495552 111497102 111499243
CMOS111433270 111433520 111434120 111436966 111457318 111460219
CPEP111778476 111782319 111783109 111786134 111801804 111804549 111806932
RCU8261290 8284010
JCU105633959 105643573
HBR110638191 110661841 110669412 110672960
MESC110602757 110604525 110612009
POP7471096 7471833 7485844 7496813
PEU105113161 105115586 105117268
PALZ118036568 118036927 118045932 118062434
JRE108990224 109006915 109010783 109010797
QSU112013582 112017450 112021180 112037120
QLO115989788 115994663
TWL120001724 120011761 120014888 120015536
VVI100252110 100256882
VRI117905942 117914818 117923686
SLY101254052 101266694 101268423
SPEN107008039 107011597 107014681
SOT102579887 102593707 102595580
CANN107840448 107859135 107868432 107878312
NTA107773919 107783485 107800019 107810649
NSY104213118 104231599 104248744
NTO104091557 104113018
NAU109212493 109229287 109232051
INI109165476 109170180 109173420
ITR116016209 116032607 116033659
SIND105167311 105175677 105178870
OEU111370903 111376809 111397120 111408284 111412215
EGT105951101 105951391 105968967
SSPL121741933 121744980 121758555 121786073 121796054 121799781 121804531 121808145
HAN110876314 110891530 110924148 110937277
ECAD122581567 122590533
LSV111908066 111909205 111909394
CCAV112505391 112519076 112526788
DCR108196538 108197008 108197172
CSIN114255796 114299829 114300037
BVG104883658 104888483
SOE110796582 110797444
CQI110690356 110697312 110706312 110728616
NNU104587693 104607047 104610624
MING122072139 122072314 122073626
TSS122640923 122651531 122670999
PSOM113289923 113295712 113308113 113311841 113334786 113358045
NCOL116255057 116262494
OSA4326670 4332646 4339732
DOSAOs01t0631100-01(Os01g0631100) Os03t0314200-01(Os03g0314200) Os05t0582100-01(Os05g0582100)
OBR102704130 102715306 102719434
BDI100824528 100825910
ATS109752464 109764228 109778378
TDC119285486 119290643 119293742 119294137 119349720
TAES123069721 123085692 123089478 123092312 123097651 123100529 123148401 123183263
TUA125528377 125551247 125551882
SBI8081057 8083814
ZMA100384114 103630788 103646881 109941464
SITA101762407 101763687 101772145 101783429
SVS117837239 117850390 117856626 117863031
PVIR120639595 120664508 120689810 120697730
PHAI112877093 112887008 112899637
PDA103703356 103709671 103712694 103715762 103719307
EGU105039974 105040999 105047196 105048749 105052613 105057317
MUS103978928 103986343 103989205 103993318
DCT110093788 110098720 110100877 110102076 110107575
PEQ110019961 110022780 110027581 110027583
AOF109831895 109834206 109841118 109842208
ATR18430921 18431457
SMOSELMODRAFT_114335 SELMODRAFT_146620
PPP112277916 112280032 112290747
CRECHLRE_09g389950v5
VCNVOLCADRAFT_106065
MNGMNEG_3646
CSLCOCSUDRAFT_12893
CVRCHLNCDRAFT_35000
APROF751_5169
OLUOSTLU_47312
OTAOT_ostta13g00470
BPGBathy02g05880
MISMICPUN_100377
MPPMICPUCDRAFT_23866 MICPUCDRAFT_54912
YLIYALI0C00187g
MGRMGG_04984
PPEIPpBr36_03356
TMNUCRPA7_6449
SSCKSPSK_06967
FGRFGSG_03124 FGSG_07886 FGSG_10575 FGSG_11677
FPUFPSE_00749 FPSE_02099 FPSE_05486 FPSE_10078 FPSE_11039
FVRFVEG_08869 FVEG_10849 FVEG_12060
FOXFOXG_03797 FOXG_09591 FOXG_12275
NHENECHADRAFT_86689 NECHADRAFT_88136
PLJVFPFJ_07752
VALVDBG_06818 VDBG_09239
VDAVDAG_00572 VDAG_05880 VDAG_07397
CFJCFIO01_03197
CHIGCH63R_02507
SAPOSAPIO_CDS5637
ELAUCREL1_5922
PFYPFICI_08038
SSLSS1G_12498
BFUBCIN_10g04340
MBEMBM_10036
PSCOLY89DRAFT_737646
GLZGLAREA_04421
PFJMYCFIDRAFT_173604
FFUCLAFUR5_08084
TMLGSTUM_00006353001
CNECNN01530
CNBCNBN1490
CNGCNAG_07937
CGICGB_N2300C
TMSTREMEDRAFT_33393
TASAA1Q1_02363
TVSTRAVEDRAFT_158505
DSQDICSQDRAFT_76151
PCOPHACADRAFT_247738
SHSSTEHIDRAFT_89745
HIRHETIRDRAFT_413711
PSQPUNSTDRAFT_57394
ADLAURDEDRAFT_109827
GTRGLOTRDRAFT_113191
MRRMoror_940
CCICC1G_10518
SCMSCHCODRAFT_42660
ABPAGABI1DRAFT66224(AGABI1DRAFT_66224)
ABVAGABI2DRAFT198117(AGABI2DRAFT_198117)
CPUTCONPUDRAFT_79031
SLASERLADRAFT_441316
WSEWALSEDRAFT_68481
WICJ056_001521
PGRPGTG_12883
MLRMELLADRAFT_22930
MBRMONBRDRAFT_24903
SREPTSG_11589
SMINv1.2.029763.t1(symbB.v1.2.029763.t1)
PTIPHATRDRAFT_20024
FCYFRACYDRAFT_157785
TPSTHAPSDRAFT_34795
NGDNGA_2075300
AAFAURANDRAFT_1346
EHXEMIHUDRAFT_450249 EMIHUDRAFT_455633 EMIHUDRAFT_97935
GTTGUITHDRAFT_79030
 » show all
Reference
1  [PMID:5446640]
  Authors
Schauer R.
  Title
[Biosynthesis of N-acetyl-O-acetylneuraminic acids. I. Incorporation of (14C) acetate into sections of the submaxillary salivary gland of ox and horse]
  Journal
Hoppe Seylers Z Physiol Chem 351:595-602 (1970)
Reference
2  [PMID:5425947]
  Authors
Schauer R.
  Title
[Biosynthesis of N-acetyl-O-acetylneuraminic acids. II. Substrate and intracellular localization of bovine acetyl-coenzyme A: N-acetylneuraminate-7- and 8-O-acetyltransferase]
  Journal
Hoppe Seylers Z Physiol Chem 351:749-58 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.45
IUBMB Enzyme Nomenclature: 2.3.1.45
ExPASy - ENZYME nomenclature database: 2.3.1.45
BRENDA, the Enzyme Database: 2.3.1.45
CAS: 9054-50-6

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