KEGG   ENZYME: 2.3.2.28
Entry
EC 2.3.2.28                 Enzyme                                 

Name
L-allo-isoleucyltransferase;
CmaE
Class
Transferases;
Acyltransferases;
Aminoacyltransferases
Sysname
L-allo-isoleucyl-[CmaA peptidyl-carrier protein]:holo-[CmaD peptidyl-carrier protein] L-allo-isoleucyltransferase
Reaction(IUBMB)
L-allo-isoleucyl-[CmaA peptidyl-carrier protein] + holo-[CmaD peptidyl-carrier protein] = L-allo-isoleucyl-[CmaD peptidyl-carrier protein] + holo-[CmaA peptidyl-carrier protein]
Reaction(KEGG)
(other) R11103
Substrate
L-allo-isoleucyl-[CmaA peptidyl-carrier protein];
holo-[CmaD peptidyl-carrier protein]
Product
L-allo-isoleucyl-[CmaD peptidyl-carrier protein];
holo-[CmaA peptidyl-carrier protein]
Comment
The enzyme, characterized from the bacterium Pseudomonas syringae, is involved in the biosynthesis of the toxin coronatine.
History
EC 2.3.2.28 created 2015
Orthology
K15647  coronamic acid synthetase CmaE, aminoacyltransferase
Genes
PST: PSPTO_4708(cmaE)
PAMG: BKM19_029790
PCAB: JGS08_03180
Reference
1  [PMID:16121186]
  Authors
Vaillancourt FH, Yeh E, Vosburg DA, O'Connor SE, Walsh CT
  Title
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis.
  Journal
Nature 436:1191-4 (2005)
DOI:10.1038/nature03797
  Sequence
Reference
2  [PMID:17530782]
  Authors
Strieter ER, Vaillancourt FH, Walsh CT
  Title
CmaE: a transferase shuttling aminoacyl groups between carrier protein domains in the coronamic acid biosynthetic pathway.
  Journal
Biochemistry 46:7549-57 (2007)
DOI:10.1021/bi700243h
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.2.28
IUBMB Enzyme Nomenclature: 2.3.2.28
ExPASy - ENZYME nomenclature database: 2.3.2.28
BRENDA, the Enzyme Database: 2.3.2.28

DBGET integrated database retrieval system