KEGG   ENZYME: 2.4.1.13Help
Entry
EC 2.4.1.13                 Enzyme                                 

Name
sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase;
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
NDP-alpha-D-glucose:D-fructose 2-alpha-D-glucosyltransferase (configuration-retaining)
Reaction(IUBMB)
NDP-alpha-D-glucose + D-fructose = NDP + sucrose [RN:R07256]
Reaction(KEGG)
Substrate
NDP-alpha-D-glucose [CPD:C15541];
D-fructose [CPD:C00095]
Product
NDP [CPD:C00454];
sucrose [CPD:C00089]
Comment
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
History
EC 2.4.1.13 created 1961, modified 2003
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
Orthology
K00695  sucrose synthase
Genes
RSS: 109440134 109440135
ATH: AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY: ARALYDRAFT_316284 ARALYDRAFT_484788 ARALYDRAFT_490342 ARALYDRAFT_493691 ARALYDRAFT_494980 ARALYDRAFT_910122
CRB: 17877054 17877643 17881746 17882355 17887544 17895033
CSAT: 104702036 104706429 104707872 104712951 104713942 104719340 104723601 104724082 104725413 104732612 104736154 104737553 104751189 104763273 104770460
EUS: EUTSA_v10003667mg EUTSA_v10012719mg EUTSA_v10018094mg EUTSA_v10027639mg EUTSA_v10028435mg
BRP: 103830752 103831821 103836763 103845641 103856465 103868315 103875021
BNA: 106345241 106348876 106353704 106354279 106355952 106365510 106371709 106376588 106383535 106386990 106402327 106406752 106407384 106434916 106451551 111210221 111211726
BOE: 106296231 106296386 106296521 106304017 106318311 106319066 106336052
THJ: 104799606 104805659 104810983 104812185 104825963 104827331
LJA: Lj0g3v0242009.1(Lj0g3v0242009.1) Lj1g3v4875640.1(Lj1g3v4875640.1) Lj1g3v4875640.2(Lj1g3v4875640.2) Lj2g3v0621550.1(Lj2g3v0621550.1) Lj2g3v2507780.1(Lj2g3v2507780.1) Lj3g3v1238910.1(Lj3g3v1238910.1) Lj4g3v2215210.1(Lj4g3v2215210.1) Lj6g3v1162830.1(Lj6g3v1162830.1) Lj6g3v1162830.2(Lj6g3v1162830.2) Lj6g3v1162840.1(Lj6g3v1162840.1) Lj6g3v1468270.1(Lj6g3v1468270.1) Lj6g3v1468270.2(Lj6g3v1468270.2) Lj6g3v2172020.1(Lj6g3v2172020.1) Lj6g3v2172020.2(Lj6g3v2172020.2)
CSV: 101203847(Sus1) 101211461(Sus4) 101213767(sus) 101216865(Sus2)
DOSA: Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
ATS: 109740648(LOC109740648) 109744619(LOC109744619) 109746065(LOC109746065) 109749305(LOC109749305) 109759549(LOC109759549) 109766888(LOC109766888) 109779202(LOC109779202)
MNG: MNEG_8846
NOC: Noc_3068
NHL: Nhal_3940
NWA: Nwat_3123
TEE: Tel_14610
TGR: Tgr7_0177
NEU: NE1214(ss2)
NET: Neut_1079
AFR: AFE_1552
ACU: Atc_1727
TEL: tlr1047
THN: NK55_01920(spsA)
AMR: AM1_6048
GVI: gvip490(spsA)
GLJ: GKIL_2834
ANA: all1059 all4985(susA)
NAZ: Aazo_0215
ANB: ANA_C11946(susA)
CTHE: Chro_5323
MRO: MROS_1314
 » show all
Taxonomy
Reference
1
  Authors
Avigad, G. and Milner, Y.
  Title
UDP-glucose:fructose transglucosylase from sugar beet roots.
  Journal
Methods Enzymol 8:341-345 (1966)
Reference
2  [PMID:14367373]
  Authors
CARDINI CE, LELOIR LF, CHIRIBOGA J.
  Title
The biosynthesis of sucrose.
  Journal
J Biol Chem 214:149-55 (1955)
Reference
3  [PMID:4624446]
  Authors
Delmer DP.
  Title
The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.
  Journal
J Biol Chem 247:3822-8 (1972)
Reference
4  [PMID:5941994]
  Authors
Murata T, Sugiyama T, Minamikawa T, Akazawa T.
  Title
Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.
  Journal
Arch Biochem Biophys 113:34-44 (1966)
DOI:10.1016/0003-9861(66)90153-6
Reference
5  [PMID:10050318]
  Authors
Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.
  Title
An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.
  Journal
Plant Cell Physiol 39:1337-41 (1998)
Reference
6  [PMID:10592030]
  Authors
Porchia AC, Curatti L, Salerno GL.
  Title
Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.
  Journal
Planta 210:34-40 (1999)
DOI:10.1007/s004250050651
Reference
7  [PMID:16653008]
  Authors
Ross HA, Davies HV.
  Title
Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.
  Journal
Plant Physiol 100:1008-1013 (1992)
Reference
8  [PMID:16661094]
  Authors
Silvius JE, Snyder FW.
  Title
Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.
  Journal
Plant Physiol 64:1070-1073 (1979)
Reference
9  [PMID:10845453]
  Authors
Tanase K, Yamaki S.
  Title
Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.
  Journal
Plant Cell Physiol 41:408-14 (2000)
DOI:10.1093/pcp/41.4.408
Reference
10 [PMID:12773636]
  Authors
Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J.
  Title
Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.
  Journal
Plant Cell Physiol 44:500-9 (2003)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.13
IUBMB Enzyme Nomenclature: 2.4.1.13
ExPASy - ENZYME nomenclature database: 2.4.1.13
BRENDA, the Enzyme Database: 2.4.1.13
CAS: 9030-05-1

DBGET integrated database retrieval system