KEGG ENZYME: 2.4.1.159

ENZYME: 2.4.1.159

Entry

EC 2.4.1.159                Enzyme

Name

flavonol-3-O-glucoside L-rhamnosyltransferase;
uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase;
UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase;
UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

UDP-beta-L-rhamnose:flavonol-3-O-beta-D-glucoside 6''-O-L-rhamnosyltransferase (configuration-inverting)

Reaction(IUBMB)

UDP-beta-L-rhamnose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [RN:R03880]

Reaction(KEGG)

R03880 > R04900 R12046

Substrate

UDP-beta-L-rhamnose [CPD:C02199];
flavonol 3-O-beta-D-glucoside [CPD:C03946]

Product

UDP [CPD:C00015];
flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [CPD:C04194]

Comment

A configuration-inverting rhamnosyltransferase that converts flavonol 3-O-glucosides to 3-O-rutinosides. Also acts, more slowly, on rutin, quercetin 3-O-galactoside and flavonol 3-O-rhamnosides.

History

EC 2.4.1.159 created 1986, modified 2015

Pathway

ec00944

Flavone and flavonol biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K22772

flavonol-3-O-glucoside L-rhamnosyltransferase

Genes

CPAP:

110821584

CIT:

102578019

CIC:	CICLE_v10004868mg

PVY:	116144158 116144201 116144250

MINC:

123216390

GRA:

105803319

GHI:

107912543

GAB:

108470982

DZI:

111313488

GMX:	100818062(FG1) 100819964(UGT79A6)

GSJ:

114402612

PVU:

137828448

VRA:

106769849

VAR:	108340918 128193350

VUN:

114189740

VUM:	124844334 124844335 124844336

CCAJ:

109804959

APRC:

113873325

MTR:	11407171 11408471 120580305

TPRA:

123913265

CAM:	101512184(UGT79A5)

PSAT:

127101155

VVO:	131601898 131601962 131606935 131614559 131630816

ADU:

107466489

AIP:

107619647

AHF:	112711420 112779780

LANG:

109336024

ZJU:	107426658 107426669

MNT:	112091444 21385665 21393595 21393596

CSAV:

115714100

RCU:

8271431

MEAN:

126666028

HBR:

110646224

MESC:

110629343

POP:

7465981

PALZ:

118043917 118043918

PNZ:

133688739

TWL:	119999971 120000591

SLY:

101244316

SPEN:

107031550

SOT:

102581417

SSTN:

125870563

SDUL:

129882623

CANN:

107861697

LBB:

132610527

NTA:	107767212 107781522 107831042

NSY:

104213556

NTO:

104084893

NAU:

109205250

INI:	109173663 109173664 109173666 109173669

ITR:	116005311 116005333

SIND:

105170545

OEU:	111379724 111382547 111405814

APAN:

127252016

HAN:	110883900 110929816

ECAD:

122608525

LSV:

111885539

CCAV:

112518423

BVG:	104908786 104908787

SOE:	110803262 110803271 110803278

CQI:	110687785 110703425 110729297

ATRI:

130827409

MOF:

131155350

MING:

122060765

TSS:	122651041 122672043

PSOM:

113279697 113296668 113300584

OSA:	136351106 4350462

DOSA:

Os11g0457000 Os11g0457300 Os11g0461300

OBR:

102707242

OGL:	127754199 127755228

BDI:	100838243 100838538

ATS:

109761553

TDC:	119344919 119362179

TAES:

123040456 123051358 123176859 123187305

TUA:

125540888

LPER:

127331319

LRD:	124667857 124676758 124677177 124679190 124683538

SBI:	8066960 8069309 8069310

ZMA:

100192114

MFLO:

136487683 136487684 136487697 136487781

SITA:

101754290 101757804 101763746 101765378

SVS:	117866571 117866745 117866826

PVIR:

120643715 120650493 120658814 120686094 120686464 120686670 120706313 120711574 120713200

PAUA:

133900474 133901053

PDA:

103698348

EGU:	105035325 105035416

MUS:

135622692

ZOF:	122008556 122017183

DCT:

110100597

PEQ:

110020195

AOF:

109839485

MSIN:

131226810 131239611 131239612 131239613 131239618

ACAK:

137951963 137952043 137952174 137952543 137953838

NCOL:

116247234 116247254 116247419 116247422 116247423 116247424 116247425 116248567 116249567 116251085 116254083 116254426 116254701 116254853

ATR:

18438253

CJF:	131036240 131040569 131066573 131068632 131874731

» show all

Reference

Authors

Kleinehollenhorst G, Behrens H, Pegels G, Srunk N, Wiermann R.

Title

Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development.

Journal

Z Natursforsch C: Biosci 37:587-599 (1982)

Reference

2 [PMID:12900416]

Authors

Jones P, Messner B, Nakajima J, Schaffner AR, Saito K

Title

UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana.

Journal

J Biol Chem 278:43910-8 (2003)
DOI:10.1074/jbc.M303523200

Other DBs

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