KEGG   ENZYME: 2.4.1.16Help
Entry
EC 2.4.1.16                 Enzyme                                 

Name
chitin synthase;
chitin-UDP N-acetylglucosaminyltransferase;
chitin-uridine diphosphate acetylglucosaminyltransferase;
chitin synthetase;
trans-N-acetylglucosaminosylase;
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase;
UDP-N-acetyl-alpha-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n = UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1 [RN:R02335 R06028]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
[(1->4)-N-acetyl-beta-D-glucosaminyl]n
Product
UDP [CPD:C00015];
[(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
Comment
Converts UDP-N-acetyl-alpha-D-glucosamine into chitin and UDP.
History
EC 2.4.1.16 created 1961
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
Orthology
K00698  chitin synthase
Genes
XLA: 108716131 108717413
XTR: 105947355
DRE: 101886093(si:ch211-264e16.1) 322468(chs1) 563138(si:ch211-219a15.4) 563347(si:ch211-264e16.2)
SRX: 107725003 107749305
SANH: 107680277 107686321 107686322 107693785
SGH: 107553936 107553937 107565902 107571073
CCAR: 109054297
IPU: 108260788(chs2) 108260789 108260790 108263942
AMEX: 103041484 103046676 107197720
LCO: 104937682 104938844
MZE: 101477217
OLA: 105357250
PRET: 103462893
NFU: 107381858
HCQ: 109531497
DME: Dmel_CG2666(kkv) Dmel_CG7464(CS-2)
DSI: Dsimw501_GD15013(Dsim_GD15013) Dsimw501_GD27435(Dsim_GD27435)
PCF: 106793893
TCA: 641504(Chs1) 641505(Chs2)
API: 100162079
DNX: 107173386
CLEC: 106666781
CEL: CELE_F48A11.1(chs-2) CELE_T25G3.2(chs-1)
CBR: CBG06966(Cbr-chs-2) CBG11891(Cbr-chs-1)
BMY: Bm1_35215
SCE: YBR023C(CHS3) YBR038W(CHS2) YNL192W(CHS1)
KMX: KLMA_10656(CHS3) KLMA_10658(CHS2) KLMA_40217(CHS1)
NCS: NCAS_0A10230(NCAS0A10230) NCAS_0A10240(NCAS0A10240) NCAS_0G01720(NCAS0G01720)
NDI: NDAI_0A07230(NDAI0A07230) NDAI_0A07240(NDAI0A07240) NDAI_0F03480(NDAI0F03480)
TPF: TPHA_0A04200(TPHA0A04200) TPHA_0F02420(TPHA0F02420) TPHA_0M00610(TPHA0M00610) TPHA_0M00620(TPHA0M00620) TPHA_0O01680(TPHA0O01680)
TBL: TBLA_0B00640(TBLA0B00640) TBLA_0B06770(TBLA0B06770) TBLA_0G02840(TBLA0G02840)
TDL: TDEL_0A01000(TDEL0A01000) TDEL_0D04000(TDEL0D04000) TDEL_0D04020(TDEL0D04020)
KAF: KAFR_0A07650(KAFR0A07650) KAFR_0C00840(KAFR0C00840) KAFR_0F02390(KAFR0F02390) KAFR_0F02410(KAFR0F02410)
PIC: PICST_29105(CHS3) PICST_29807(CSH8) PICST_42812(CHS1) PICST_51281(CHS2.2) PICST_65597(CHS2)
SLB: AWJ20_1163(CHS2) AWJ20_12(CHS3) AWJ20_13(CHS3) AWJ20_1500(CHS2) AWJ20_1501 AWJ20_3769(CHS1) AWJ20_4861(CHS3) AWJ20_4948(CHS3)
NCR: NCU03611(chs-1) NCU04251(chs-3) NCU04350 NCU04352(chs-5) NCU05239 NCU05268(chs-6) NCU09324(chs-4)
NTE: NEUTE1DRAFT121615(NEUTE1DRAFT_121615) NEUTE1DRAFT127954(NEUTE1DRAFT_127954) NEUTE1DRAFT60883(NEUTE1DRAFT_60883) NEUTE1DRAFT60887(NEUTE1DRAFT_60887) NEUTE1DRAFT72792(NEUTE1DRAFT_72792) NEUTE1DRAFT75235(NEUTE1DRAFT_75235) NEUTE1DRAFT80490(NEUTE1DRAFT_80490)
ANG: ANI_1_120124(An14g00660) ANI_1_1214104(An12g10380) ANI_1_1542034(An03g06360) ANI_1_1986074(An08g05290) ANI_1_2332024(An02g02360) ANI_1_252084(An09g02290) ANI_1_316024(An02g02340) ANI_1_498084(An09g04010) ANI_1_684064(An07g05570)
PNO: SNOG_04257(SNOG_04256) SNOG_05499 SNOG_05925(SNOG_05923 SNOG_05924) SNOG_06555 SNOG_12685 SNOG_13325 SNOG_13326 SNOG_13479(SNOG_13478)
SPO: SPAC13G6.12c(chs1) SPBC1709.01(chs2)
ABP: AGABI1DRAFT113517(AGABI1DRAFT_113517) AGABI1DRAFT119421(AGABI1DRAFT_119421) AGABI1DRAFT31788(AGABI1DRAFT_31788) AGABI1DRAFT52110(AGABI1DRAFT_52110) AGABI1DRAFT64444(AGABI1DRAFT_64444) AGABI1DRAFT70953(AGABI1DRAFT_70953) AGABI1DRAFT75713(AGABI1DRAFT_75713) AGABI1DRAFT91131(AGABI1DRAFT_91131)
ABV: AGABI2DRAFT187535(AGABI2DRAFT_187535) AGABI2DRAFT191834(AGABI2DRAFT_191834) AGABI2DRAFT203819(AGABI2DRAFT_203819) AGABI2DRAFT212165(AGABI2DRAFT_212165) AGABI2DRAFT213484(AGABI2DRAFT_213484) AGABI2DRAFT221343(AGABI2DRAFT_221343) AGABI2DRAFT230160(AGABI2DRAFT_230160) AGABI2DRAFT60607(AGABI2DRAFT_60607)
EHI: EHI_170480(186.t00006)
FCY: FRACYDRAFT_264943(CHS1)
AVI: Avi_3564
 » show all
Taxonomy
Reference
1  [PMID:13475355]
  Authors
GLASER L, BROWN DH.
  Title
The synthesis of chitin in cell-free extracts of Neurospora crassa.
  Journal
J Biol Chem 228:729-42 (1957)
Reference
2  [PMID:2945823]
  Authors
Sburlati A, Cabib E.
  Title
Chitin synthetase 2, a presumptive participant in septum formation in Saccharomyces cerevisiae.
  Journal
J Biol Chem 261:15147-52 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.16
IUBMB Enzyme Nomenclature: 2.4.1.16
ExPASy - ENZYME nomenclature database: 2.4.1.16
BRENDA, the Enzyme Database: 2.4.1.16
CAS: 9030-18-6

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