KEGG   ENZYME: 2.4.1.179
Entry
EC 2.4.1.179                Enzyme                                 
Name
lactosylceramide beta-1,3-galactosyltransferase;
uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase;
UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase;
UDP-galactose:D-galactosyl-(1->4)-beta-D-glucosyl-R 3-beta-galactosyltransferase;
UDP-alpha-D-galactose:D-galactosyl-(1->4)-beta-D-glucosyl-R 3-beta-galactosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-galactose:beta-D-galactosyl-(1->4)-beta-D-glucosyl-R 3-beta-galactosyltransferase
Reaction(IUBMB)
UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-D-glucosyl-R = UDP + beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R [RN:R04431]
Reaction(KEGG)
R04431
Substrate
UDP-alpha-D-galactose [CPD:C00052];
beta-D-galactosyl-(1->4)-beta-D-glucosyl-R [CPD:C04247]
Product
UDP [CPD:C00015];
beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R [CPD:C04775]
Comment
R may be an oligosaccharide or a glycolipid; lactose can also act as acceptor, but more slowly. Involved in the elongation of oligosaccharide chains, especially in glycolipids.
History
EC 2.4.1.179 created 1989
Reference
1  [PMID:3129295]
  Authors
Bailly P, Piller F, Cartron JP.
  Title
Characterization and specific assay for a galactoside beta-3-galactosyltransferase of human kidney.
  Journal
Eur J Biochem 173:417-22 (1988)
DOI:10.1111/j.1432-1033.1988.tb14015.x
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.179
IUBMB Enzyme Nomenclature: 2.4.1.179
ExPASy - ENZYME nomenclature database: 2.4.1.179
BRENDA, the Enzyme Database: 2.4.1.179
CAS: 106769-64-6

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (3)   
   RefSeq(nuc) (2)   
   GenBank (1)   
All databases (12)   

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