KEGG   ENZYME: 2.4.1.202
Entry
EC 2.4.1.202                Enzyme                                 
Name
2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase;
uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase;
BX8;
BX9;
benzoxazinoid glucosyltransferase;
DIMBOA glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-beta-D-glucosyltransferase
Reaction(IUBMB)
(1) UDP-alpha-D-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one = UDP + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:R04579];
(2) UDP-alpha-D-glucose + 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one = UDP + (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:R07426]
Reaction(KEGG)
R04579 R07426
Substrate
UDP-alpha-D-glucose [CPD:C00029];
2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one [CPD:C04720];
2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one [CPD:C15770]
Product
UDP [CPD:C00015];
(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C04831];
(2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C15772]
Comment
The enzyme is involved in the detoxification of the benzoxazinoids DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one) which are stored as the respective non-toxic glucosides in the vacuoles in some plants, most commonly from the family of Poaceae (grasses). Benzoxazinoids are known to exhibit antimicrobial, antifeedant, and antiinsecticidal effects and are involved in the interaction of plants with other plants, insects, or microorganisms.
History
EC 2.4.1.202 created 1992, modified 2012
Pathway
ec00402  Benzoxazinoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K13227  UDP-glucosyltransferase BX8/BX9
Genes
OSA4342809 4350429
DOSAOs11t0444000-01(Os11g0444000)
OBR102699351 102716206
BDI100830893
ATS109735346 109736907 109754422
TDC119314690 119315414 119328279 119330805 119334371 119336035 119336866 119340106 119341052 119349903 119349904
TAES100682422 123147887 123150283 123150314 123159126 123160005 123167683 123172831
SBI110430107 8069138
ZMA100274317 100277344 103632152
SITA101752637 101753321 101778310 101780325
SVS117859511
PVIR120644461 120644612 120684540 120684928 120696099
PHAI112897861
 » show all
Reference
1  [PMID:16666853]
  Authors
Bailey BA, Larson RL
  Title
Hydroxamic Acid glucosyltransferases from maize seedlings.
  Journal
Plant Physiol 90:1071-6 (1989)
DOI:10.1104/pp.90.3.1071
  Sequence
[zma:100274317]
Reference
2  [PMID:11851909]
  Authors
von Rad U, Huttl R, Lottspeich F, Gierl A, Frey M.
  Title
Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize.
  Journal
Plant J 28:633-42 (2001)
DOI:10.1046/j.1365-313x.2001.01161.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.202
IUBMB Enzyme Nomenclature: 2.4.1.202
ExPASy - ENZYME nomenclature database: 2.4.1.202
BRENDA, the Enzyme Database: 2.4.1.202
CAS: 122544-56-3

DBGET integrated database retrieval system