KEGG   ENZYME: 2.4.1.253
Entry
EC 2.4.1.253                Enzyme                                 
Name
baicalein 7-O-glucuronosyltransferase;
UBGAT
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-D-glucuronate:5,6,7-trihydroxyflavone 7-O-glucuronosyltransferase
Reaction(IUBMB)
UDP-D-glucuronate + baicalein = UDP + baicalin [RN:R09529]
Reaction(KEGG)
R09529
Substrate
UDP-D-glucuronate [CPD:C00167];
baicalein [CPD:C10023]
Product
UDP [CPD:C00015];
baicalin [CPD:C10025]
Comment
The enzyme is specific for UDP-D-glucuronate as a sugar donor and flavones with substitution ortho- to the 7-OH group such as baicalein (6-OH), scutellarein (6-OH) and wogonin (8-OMe).
History
EC 2.4.1.253 created 2011
Orthology
K21370  baicalein 7-O-glucuronosyltransferase
Genes
SIND: 105160417
EGT: 105971846 105973231
SSPL: 121780846
APAN: 127248985 127256140 127256422
Reference
1  [PMID:10724177]
  Authors
Nagashima S, Hirotani M, Yoshikawa T
  Title
Purification and characterization of UDP-glucuronate: baicalein 7-O-glucuronosyltransferase from Scutellaria baicalensis Georgi. cell suspension cultures.
  Journal
Phytochemistry 53:533-8 (2000)
DOI:10.1016/S0031-9422(99)00593-2
  Sequence
[ag:BAC98300]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.253
IUBMB Enzyme Nomenclature: 2.4.1.253
ExPASy - ENZYME nomenclature database: 2.4.1.253
BRENDA, the Enzyme Database: 2.4.1.253

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (8)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (20)   

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