KEGG ENZYME: 2.4.1.257

ENZYME: 2.4.1.257

Entry

EC 2.4.1.257                Enzyme

Name

GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase;
GDP-Man:Man2GlcNAc2-PP-Dol alpha-1,6-mannosyltransferase;
Alg2 mannosyltransferase (ambiguous);
ALG2 (gene name, ambiguous);
GDP-Man:Man1GlcNAc2-PP-dolichol mannosyltransferase (ambiguous);
GDP-D-mannose:D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-6-mannosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

GDP-alpha-D-mannose:alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol 6-alpha-D-mannosyltransferase (configuration-retaining)

Reaction(IUBMB)

GDP-alpha-D-mannose + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol = GDP + alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol [RN:R06238]

Reaction(KEGG)

R06238(G)

Substrate

GDP-alpha-D-mannose [CPD:C00096];
alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol

Product

GDP [CPD:C00035];
alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol

Comment

The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an alpha1,3-mannosylation (cf. EC 2.4.1.132) of beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol, followed by an alpha1,6-mannosylation, to form the first branched pentasaccharide intermediate of the dolichol pathway [1,2].

History

EC 2.4.1.257 created 2011, modified 2012

Pathway

ec00510

N-Glycan biosynthesis

ec00513

Various types of N-glycan biosynthesis

ec01100

Metabolic pathways

Orthology

K03843

alpha-1,3/alpha-1,6-mannosyltransferase

Genes

HSA:	85365(ALG2)

PTR:	472993(ALG2)

PPS:	100984805(ALG2)

GGO:	101128869(ALG2)

PON:	100451740(ALG2)

PPYG:

129043777(ALG2)

NLE:	100593183(ALG2)

HMH:	116475324(ALG2)

SSYN:

129479110(ALG2)

MCC:	714850(ALG2)

MCF:	102146841(ALG2)

MTHB:

126938062

MNI:	105477214(ALG2)

CSAB:

103219138(ALG2)

CATY:

105593038(ALG2)

PANU:

101016143(ALG2)

TGE:	112608307(ALG2)

MLEU:

105549298(ALG2)

RRO:	104657764(ALG2)

RBB:	108512462(ALG2)

TFN:	117065914 117098926(ALG2)

PTEH:

111536438(ALG2)

CANG:

105509957(ALG2)

CJC:	100388149(ALG2)

SBQ:	101030903(ALG2)

CIMI:

108303876(ALG2)

ANAN:

105712992(ALG2)

CSYR:

103253383(ALG2)

MMUR:

105873779(ALG2)

LCAT:

123646708(ALG2)

PCOQ:

105805402(ALG2)

OGA:	100953631(ALG2)

MMU:	56737(Alg2)

MCAL:

110292619(Alg2)

MPAH:

110323013(Alg2)

RNO:	313231(Alg2)

MCOC:

116095984(Alg2)

ANU:	117709283(Alg2)

MUN:	110556434(Alg2)

CGE:	100768412(Alg2)

MAUA:

101839398(Alg2)

PROB:

127224671(Alg2)

PLEU:

114702343(Alg2)

MORG:

121458504(Alg2)

MFOT:

126509850

AAMP:

119826465(Alg2)

NGI:	103749080(Alg2)

HGL:	101717738(Alg2)

CPOC:

100715517(Alg2)

CCAN:

109691420(Alg2)

DORD:

105990835(Alg2)

DSP:	122121584(Alg2)

PLOP:

125345928(Alg2)

NCAR:

124964703

MMMA:

107147759(Alg2)

OCU:

100353637

OPI:	101532676(ALG2)

TUP:	102477233(ALG2)

GVR:	103587309(ALG2)

CFA:	474780(ALG2)

CLUD:

112649858(ALG2)

VVP:	112930771(ALG2)

VLG:	121495941(ALG2)

NPO:	129495113(ALG2)

AML:	100471257(ALG2)

UMR:	103678628(ALG2)

UAH:	113260403(ALG2)

UAR:	123781131(ALG2)

ELK:

111145785

LLV:

125083603

MPUF:

101691293(ALG2)

MNP:	132024565(ALG2)

MLK:	131812498(ALG2)

NVS:	122917412(ALG2)

ORO:	101379758(ALG2)

EJU:	114213576(ALG2)

ZCA:	113934424(ALG2)

MLX:	118017897(ALG2)

NSU:	110581325(ALG2)

LWW:

102749316

FCA:	101084066(ALG2)

PYU:	121034736(ALG2)

PCOO:

112849425(ALG2)

PBG:	122475346(ALG2)

PVIV:

125150503(ALG2)

LRUF:

124502330

PTG:	102963679(ALG2)

PPAD:

109270077(ALG2)

PUC:

125920188

AJU:

106972044

HHV:	120233506(ALG2)

BTA:	538899(ALG2)

BOM:	102282554(ALG2)

BIU:	109563080(ALG2)

BBUB:

102397326(ALG2)

BBIS:

104993683(ALG2)

CHX:	102172999(ALG2)

OAS:	101101953(ALG2)

BTAX:

128052597(ALG2)

ODA:	120862795(ALG2)

CCAD:

122453211(ALG2)

MBEZ:

129556860(ALG2)

SSC:	100113423(ALG2)

CFR:	102523932(ALG2)

CBAI:

105067394(ALG2)

CDK:	105086888(ALG2)

VPC:	102526113(ALG2)

BACU:

102999901(ALG2)

BMUS:

118896923(ALG2)

LVE:	103071670(ALG2)

OOR:	101287811(ALG2)

DLE:	111188084(ALG2)

PCAD:

102982177(ALG2)

PSIU:

116755849(ALG2)

NASI:

112392634(ALG2)

ECB:	100054840(ALG2)

EPZ:	103555265(ALG2)

EAI:	106842922(ALG2)

MYB:	102241662(ALG2)

MYD:	102764897(ALG2)

MMYO:

118667261(ALG2)

MLF:	102432865(ALG2)

MDT:	132212193(ALG2)

PKL:	118716262(ALG2)

EFUS:

103286582(ALG2)

MNA:	107544878(ALG2)

DRO:	112304450(ALG2)

SHON:

118979624(ALG2)

AJM:	119045936(ALG2)

PDIC:

114497826(ALG2)

PHAS:

123819837(ALG2)

MMF:	118629745(ALG2)

PPAM:

129079395(ALG2)

HAI:	109386428(ALG2)

RFQ:	117032213(ALG2)

PALE:

102880508(ALG2)

PGIG:

120597193(ALG2)

PVP:	105296247(ALG2)

RAY:	107500590(ALG2)

MJV:	108394149(ALG2)

TOD:	119231085(ALG2)

SARA:

101551872(ALG2)

SETR:

126003771(ALG2)

LAV:	100655996(ALG2)

TMU:

101352514

ETF:	101657439(ALG2)

DNM:	101413327(ALG2)

MDO:	100011371(ALG2)

GAS:	123231023(ALG2)

SHR:	100913580(ALG2)

AFZ:

127541482

PCW:	110214538(ALG2)

TVP:	118830981(ALG2)

OAA:	100092424(ALG2)

GGA:	420998(ALG2)

PCOC:

116226269(ALG2)

MGP:	100538726(ALG2)

CJO:	107309970(ALG2)

TPAI:

128091162(ALG2)

LMUT:

125690955(ALG2)

NMEL:

110393668(ALG2)

APLA:

101795871(ALG2)

ACYG:

106035960(ALG2)

CATA:

118249995(ALG2)

AFUL:

116485622(ALG2)

TGU:	100190655(ALG2)

LSR:	110469741(ALG2)

SCAN:

103826142(ALG2)

PMOA:

120502985(ALG2)

OTC:	121337769(ALG2)

PRUF:

121358421(ALG2)

GFR:	102032538(ALG2)

FAB:	101820728(ALG2)

OMA:	130249503(ALG2)

PHI:	102103653(ALG2)

PMAJ:

107200761(ALG2)

CCAE:

111925280(ALG2)

CCW:	104685901(ALG2)

CBRC:

103623578(ALG2)

ETL:	114058961(ALG2)

ZAB:	102062934(ALG2)

ZLE:	135444283(ALG2)

ACHL:

103811981(ALG2)

SVG:	106852514(ALG2)

MMEA:

130574859(ALG2)

HRT:	120754081(ALG2)

SATI:

136366688(ALG2)

FPG:	101912340(ALG2)

FCH:	102058016(ALG2)

CCRI:

104154868(ALG2)

NNT:	104399423(ALG2)

SHAB:

115604824(ALG2)

ACUN:

113477198(ALG2)

TALA:

104367215(ALG2)

ACHC:

115340463(ALG2)

HALD:

104321685(ALG2)

AGEN:

126051345

GCL:

127013241

CSTI:

104559755(ALG2)

LDI:	104340306(ALG2)

MNB:	103779252(ALG2)

DPUB:

104306078(ALG2)

AVIT:

104267967(ALG2)

BRHI:

104490288(ALG2)

EGZ:	104130440(ALG2)

NNI:	104018204(ALG2)

PCRI:

104024256(ALG2)

PCAO:

104048612(ALG2)

PADL:

103917756(ALG2)

AFOR:

103896778(ALG2)

FGA:	104082898(ALG2)

GSTE:

104264638(ALG2)

CLV:	102093093(ALG2)

MUI:	104538893(ALG2)

PGUU:

104470034(ALG2)

PLET:

104622213(ALG2)

EHS:	104505145(ALG2)

CMAC:

104473388(ALG2)

CUCA:

104062181(ALG2)

TEO:	104381440(ALG2)

BREG:

104629888(ALG2)

OHA:	104334051(ALG2)

ACAR:

104528197(ALG2)

CPEA:

104389318(ALG2)

CVF:	104287235(ALG2)

RTD:	128905145(ALG2)

AAM:	106496984(ALG2)

AROW:

112960650(ALG2)

NPD:	112951470(ALG2)

TGT:	104572970(ALG2)

DNE:	112988246(ALG2)

ASN:	102370298(ALG2)

AMJ:	102564853(ALG2)

CPOO:

109313297(ALG2)

GGN:	109291919(ALG2)

PSS:	102460786(ALG2)

CMY:	102940919(ALG2)

CCAY:

125631925(ALG2)

DCC:	119851318(ALG2)

CPIC:

101942628(ALG2)

TST:	117872687(ALG2)

CABI:

116828726(ALG2)

MRV:	120399027(ALG2)

ACS:	103279177(alg2)

ASAO:

132778484(ALG2)

PVT:	110086078(ALG2)

SUND:

121933614(ALG2)

PBI:	103051382(ALG2)

PMUR:

107291673(ALG2)

CTIG:

120314776(ALG2)

TSR:	106538359(ALG2)

PGUT:

117664925(ALG2)

APRI:

131198495(ALG2)

PTEX:

113437393(ALG2)

NSS:	113419094(ALG2)

VKO:	123035063(ALG2)

PMUA:

114582036(ALG2)

PRAF:

128399846(ALG2)

ZVI:	118094544(ALG2)

HCG:	128331805(ALG2)

GJA:	107110593(ALG2)

EMC:	129337558(ALG2)

XLA:	446622(alg2.L)

XTR:	595052(alg2)

NPR:	108797276(ALG2)

RTEM:

120940466(ALG2)

BBUF:

121001845(ALG2)

BGAR:

122938450(ALG2)

MUO:	115471473(ALG2)

GSH:	117353561(ALG2)

DRE:	403068(alg2)

SRX:	107706186 107706481 107723517

SANH:

107657723 107687815

SGH:	107593685 107595974

CAUA:

113116633(alg2)

CGIB:

127975126

PTET:

122360935(alg2)

LROH:

127178767(alg2)

OMC:	131522491(alg2)

PPRM:

120484510(alg2)

RKG:	130084218(alg2)

MAMB:

125243553(alg2)

CIDE:

127497526

CERY:

137027139(alg2)

MASI:

127453938

TROS:

130557963(alg2)

TDW:	130432292(alg2)

MANU:

129448068(alg2)

IPU:

108256665

IFU:	128599786(alg2)

PHYP:

113532962(alg2)

SMEO:

124375490(alg2)

TFD:	113660411(alg2)

TVC:	132840478(alg2)

TRN:	134300958(alg2)

AMEX:

103028771(alg2)

CMAO:

118798727(alg2)

EEE:	113590840(alg2)

CHAR:

105893979(alg2)

TRU:	101076494(alg2)

TFS:	130532585(alg2)

TNG:	GSTEN00034041G001

LCO:	104923022(alg2)

NCC:	104966077(alg2)

TBEN:

117480177(alg2)

CGOB:

115021108(alg2)

PGEO:

117461004(alg2)

GACU:

117553993(alg2)

EMAC:

134862229(alg2)

ELY:	117266145(alg2)

EFO:	125893572(alg2)

PLEP:

121946296(alg2)

SLUC:

116049473(alg2)

ECRA:

117946017(alg2)

ESP:	116690987(alg2)

PFLV:

114557172(alg2)

GAT:	120810628(alg2)

PPUG:

119197841(alg2)

AFB:	129109621(alg2)

CLUM:

117745301(alg2)

PSWI:

130212957(alg2)

MSAM:

119897673(alg2)

SCHU:

122881297(alg2)

CUD:	121513077(alg2)

ALAT:

119006254(alg2)

ASTR:

137601653(alg2)

MZE:	101484363(alg2)

ONL:	100701749(alg2)

OAU:	116331328(alg2)

OLA:	101167069(alg2)

OML:	112143391(alg2)

CSAI:

133431037(alg2)

XMA:	102222028(alg2)

XCO:	114141939(alg2)

XHE:	116717677(alg2)

PRET:

103478647(alg2)

PFOR:

103140872(alg2)

PLAI:

106945979(alg2)

PMEI:

106923156(alg2)

GAF:	122831194(alg2)

PPRL:

129371567(alg2)

CVG:	107102914(alg2)

CTUL:

119787286(alg2)

GMU:	124865735(alg2)

NFU:	107379741(alg2)

KMR:	108241118(alg2)

ALIM:

106527090(alg2)

NWH:	119409428(alg2)

AOCE:

111577777(alg2)

MCEP:

125017018(alg2)

CSEM:

103388137(alg2)

POV:	109633440(alg2)

SSEN:

122774820(alg2)

HHIP:

117776915(alg2)

HSP:	118113903(alg2)

PPLT:

128448877(alg2)

SMAU:

118306629(alg2)

LCF:

108889631

SDU:	111236927(alg2)

SLAL:

111650852(alg2)

XGL:	120784287(alg2)

HCQ:	109515460(alg2)

SSCV:

125975408

SBIA:

133500597(alg2)

PEE:	133401648(alg2)

PTAO:

133479550(alg2)

BPEC:

110171549(alg2)

MALB:

109964158(alg2)

BSPL:

114843469(alg2)

SJO:	128366103(alg2)

SASA:

106574526 106606060

STRU:

115181021 115184291

OTW:	112240345(alg2)

OMY:	110508156(alg2) 110520778

OGO:	124016995(alg2)

ONE:	115115907(alg2)

OKI:	109877815(alg2)

OKE:	118380404 127927171

SALP:

112076465(alg2)

SNH:	120030766(alg2) 120031113

CCLU:

121543255 123482087

ELS:	105018904(alg2)

SFM:	108940512(alg2)

PKI:	111845856(alg2)

AANG:

118225493(alg2)

LOC:	102683945(alg2)

PSPA:

121308936 121314690(alg2)

ARUT:

117399927 117435770

PSEX:

120515404(alg2)

LCM:	102353262(ALG2)

CMK:	103181173(alg2)

RTP:	125485321(alg2)

CPLA:

122549875(alg2)

HOC:	132815723(alg2)

LERI:

129713910(alg2)

PMRN:

116937018(ALG2)

BFO:

118431347

BBEL:

109483556

CIN:

100180226

SCLV:

120335572

SPU:	115928701 589943

LPIC:

129271001 129271004

APLC:

110977698

ARUN:

117297315

AJC:

117118505

SKO:

100371989

DME:	Dmel_CG1291(Alg2)

DER:

6543647

DSE:

6610565

DSI:	Dsimw501_GD13727(Dsim_GD13727)

DYA:	Dyak_GE20359

DAN:

6506901

DSR:

110182775

DPO:

4812504

DPE:

113566407

DMN:

108151759

DWI:

6646055

DGR:

6558083

DMO:	Dmoj_GI12600

DAZ:

108613374

DNV:

108651329

DHE:

111591933

DVI:

6623162

CCAT:

101456029

BOD:

106625406

BDR:

115065705

RZE:

108364224

AOQ:	129240397 129240726

TDA:

119668099

MDE:

101891935

SCAC:

106090784

LCQ:

111680696

LSQ:

119609888

GFS:

119633260

ECOE:

129943974

CLON:

129613037

HIS:

119660205

AGA:

1281939

ACOZ:

120949329

AARA:

120896938

AMER:

121588577

ASTE:

118508435

AFUN:

125761537

AMOU:

128296849

AALI:

118458516

AAG:

5575716

AALB:

109431792

ASUA:

134226890

CPII:

120412984

CNS:

116347693

BCOO:

119066898 119076089

LLL:

129787805

AME:

551972

ACER:

107993202

ALAB:

122716325

ADR:

102672192

AFLR:

100863706

BIM:

100740485

BBIF:

117207965

BVK:

117234131

BVAN:

117158887

BTER:

100647541

BAFF:

126920259

BPYO:

122570986

BPAS:

132906304

FVI:

122531038

CCAL:

108626003

OBB:

114878353

OLG:

117606249

MGEN:

117227794

NMEA:

116429331

CGIG:

122396791

SOC:

105207380

MPHA:

105838058

AEC:

105149006

ACEP:

105622020

PBAR:

105433355

VEM:

105565242

HST:

105192054

DQU:

106751846

CFO:

105249015

FEX:

115240641

LHU:	105679897(Alg2)

PGC:

109862973

OBO:

105288046

PCF:

106784395

PFUC:

122520151

VPS:

122630830

VCRB:

124424519

VVE:

124950281

NVI:

100122589

CSOL:

105367225

TPRE:

106657594

LHT:

122499322

LBD:

127277239

MDL:

103576080

CGLO:

123259282

DAM:

107039314

AGIF:

122853890

CINS:

118074706

VCAN:

122413521

CCIN:

107267020

DSM:

124407983

NPT:

124217502

NFB:

124181322

NLO:

107223631

NVG:

124303792

AROA:

105693402

TCA:

657332

DPA:	109544912 109546697

SOY:	115876138 115876261 115887699

AGRG:

126743631 126747297

ATD:	109601758 109607356

CSET:

123308702 123322596

AGB:	108912131 108917327

LDC:	111502256 111515761

DVV:	114341477 126885913

NVL:	108560004 108560581

APLN:

108732731 108740606

PPYR:

116164205 116181116

OTU:	111414090 111427649

BMOR:

101737122

BMAN:

114250453

MSEX:

115452020

DPL:	KGM_212052

BANY:

112046855

MJU:

123876798

NIQ:

126776365

VCD:

124538859

MCIX:

123664041

PMAC:

106707690

PPOT:

106104083

PXU:

106116765

PRAP:

110992446

PBX:

123713541

PNAP:

125051802

ZCE:

119828916

CCRC:

123700878

LSIN:

126971835 126971836

AAGE:

121736123

HAW:

135116570

HZE:

124640857

TNL:

113499527

SLIU:

111362062

OFU:

114357487

ATRA:

106131623

GMW:

113520296

PXY:

105390412

PGW:

126380572

LGLY:

125225949

CFEL:

113383117

CCRN:

123300429

API:

100164916

DNX:

107167633

AGS:

114128688

RMD:

113547805

ACOO:

126838455

DVT:

126900207

BTAB:

109044497

DCI:

103512674

CLEC:

106662501

HHAL:

106683478(Alg2)

NLU:	111047421 120348864 120352311

HVI:	124360404 124371861

MQU:

128993451

PHU:	Phum_PHUM599360

FOC:

113210664

TPAL:

117652725

ZNE:

110826715

CSEC:

111864909

SGRE:

126293494

BROR:

134532769

IEL:

124165679

FCD:

110848787

DPX:	DAPPUDRAFT_192054

DMK:

116927441

DPZ:

124315359

PVM:

113807059

PJA:

122260920

PCHN:

125034274

HAME:

121856376

PCLA:

123772706

CQD:

128692820

PTRU:

123513292

ESN:

126984222

MNZ:

135224633

MRJ:	136847650(Alg2)

HAZT:

108674391

EAF:

111706104

LSM:

121125360

TCF:

131886790

PPOI:

119112315 119112450

DSV:	119433490 119433547

RSAN:

119405944

RMP:

119181926

VDE:

111249255

VJA:

111259264

TUT:

107361675

DPTE:

113792811

DFR:

124492463

CSCU:

111618264 111618267

CVS:	136973740(Alg2)

PTEP:

107448020

ABRU:

129957103 129957314

UDV:

129232586

SDM:

118179346

LPOL:

106458576

PMEO:

129589083

CEL:	CELE_F09E5.2(algn-2)

CBR:

CBG_02380

CRQ:	GCK72_006007

NAI:	NECAME_06664

BMY:	BM_BM3222(Bma-algn-2)

LOA:	LOAG_01337 LOAG_02361

TSP:	Tsp_11159 Tsp_11653

HRO:	HELRODRAFT_110729

LGI:	LOTGIDRAFT_224255

PVUL:

126817836

PCAN:

112574345

BGT:

106061540

GAE:

121390597

HRF:

124112788

HRJ:

124263783

CRG:

105336633

CANU:

128167232

CVN:

111121100

OED:

125667890

MYI:

110458513

PMAX:

117325504

MCAF:

127727717

MMER:

123525895

RPHI:

132734480

DPOL:

127862194 127862442

MAEA:

128213266 128214916

OBI:

106873336

OSN:

115226563

LJP:

135470019

LAK:	106155289 106164980

SMM:	Smp_177080

SHX:	MS3_00005848(ALG2_1)

OVI:	T265_04788

EGL:

EGR_09601

LLON:

135486333

NVE:

5517178

EPA:

110235219

ATEN:

116293053

ADF:

107335169

AMIL:

114952865

SPIS:

111340459

DGT:	114533068 114534204

XEN:

124445137

HMG:

101238397

HSY:

130629583

RES:

135694306

AQU:

100632336

ATH:

AT1G78800

ALY:

9325273

CRB:

17894620

CSAT:

104703214 104752305

EUS:	EUTSA_v10007837mg EUTSA_v10019736mg

BRP:

103832355

BNA:	106354674 125589180

BOE:

106298287

RSZ:

108843430

THJ:

104812317

CPAP:

110812537

CIT:

102626306

CIC:	CICLE_v10020399mg

PVY:

116145490

MINC:

123195863 123202187

TCC:

18594241

GRA:

105777281

GHI:	107917782 107944455

GAB:

108480381

HSYR:

120160204 120219440

DZI:	111275922 111275924

EGR:

104448547

GMX:	100800839 100809168

GSJ:	114373873 114379181

PVU:	PHAVU_005G081600g

VRA:

106778117

VAR:

108321952

VUN:

114183384

VUM:

124840890

CCAJ:

109811934

APRC:

113856153

MTR:

11420245

TPRA:

123882947

CAM:

101501052

PSAT:

127097121

VVO:

131643450

LJA:	130724543 130742589

ADU:	107458069 107459779

AIP:	107609313 107613290

AHF:	112703598 112765901 112770879

LANG:

109348100 109357267

PCIN:

129300251 129313205

QSA:	O6P43_001051 O6P43_029191

FVE:

101292974

RCN:

112165984

PPER:

18778069 18779540

PMUM:

103328865 103342728

PAVI:

110754544 110771820

PDUL:

117624966 117626722 117627893

MDM:

103448776

MSYL:

126589953

PXB:

103934886

ZJU:	107403902 107432555

MNT:

21387854

CSAV:

115722419 115722420

CSV:	101211733 101222455

CMO:

103492951

BHJ:

120084069

MCHA:

111012924

CMAX:

111480394

CMOS:

111447959

CPEP:

111781399

RCU:

8276386

MEAN:

126670416

JCU:

105637031

HBR:	110670322 110670335 110671298

MESC:

110612091

POP:

7472343

PEU:

105139363

PALZ:

118038297

PNZ:

133702632

JRE:

109012141

CILL:

122281435

CAVE:

132175552

QSU:

112040101

QLO:

115949589

TWL:	119985079 120005458

VVI:

100248737

VRI:

117908077

SLY:

101245960

SPEN:

107021358

SOT:

102603181

SSTN:

125874482

SDUL:

129901212

CANN:

107875413

LBB:

132606561

NTA:	107792493 107828501

NSY:

104220522

NTO:

104117000

NAU:	109211705 109228734

INI:	109163384 109175932

ITR:	116001603 116032061

SIND:

105176930

OEU:	111370834 111395563

EGT:

105970446

SSPL:

121749753 121752409 121784236 121788064

SMIL:

131012082

SHIS:

125186878 125214228

APAN:

127241481

HAN:	110912910 110937378

ECAD:

122588828 122600348

LSV:

111913826

CCAV:

112507996

DCR:	108202889 108219428

CSIN:

114289706

RVL:	131317023 131317606 131323407 131331508 131331509

AEW:	130754678 130762743

BVG:	104884065 104884652

SOE:

110794643

CQI:	110734009 110737800

ATRI:

130802775

MOF:	131151262 131157230

NNU:

104607825

MING:

122094143

TSS:

122667170

PSOM:

113283309 113356237

OSA:

4336813

OBR:

102720873

OGL:

127769570

BDI:

100838439

ATS:

109741247

TDC:	119356401 119365581

TAES:

123046653 123054521 123190372

TUA:

125537614

LPER:

127336558

LRD:	124674393 124675349

SBI:

8060461

ZMA:

100279297

MFLO:

136493338 136493563

SITA:

101773290 101779913 101784521

SVS:	117841480 117859917 117864162

PVIR:

120641602 120682782 120706159

PHAI:

112899126

PDA:

103696780

EGU:	105033909 105043944

MUS:

103983835

ZOF:	122042231 122046759

DCT:

110094921

PEQ:

110034058

AOF:	109825622 109826114

MSIN:

131252651

NCOL:

116247805

ATR:

18445550

SMO:	SELMODRAFT_419620(GT4A5)

PPP:

112289303

CRE:	CHLRE_02g095147v5

VCN:	VOLCADRAFT_67522

MNG:	MNEG_12470

CSL:	COCSUDRAFT_12084

CVR:	CHLNCDRAFT_56004

APRO:

F751_4445

OLU:	OSTLU_119517(alg2)

OTA:	OT_ostta02g00860

BPG:	Bathy14g01700(ALG2)

MIS:	MICPUN_113380

MPP:	MICPUCDRAFT_70800

CME:	CYME_CMT168C

GSL:	Gasu_57500

CCP:	CHC_T00007099001

SCE:	YGL065C(ALG2)

SEUB:

DI49_1904

SPAO:

SPAR_G01760

AGO:	AGOS_AFL098W

ERC:

Ecym_2197

KLA:	KLLA0_B02420g

KMX:	KLMA_40539(ALG2)

LTH:	KLTH0H04070g

VPO:	Kpol_1002p49

ZRO:	ZYRO0C13354g

CGR:	2891643(GVI51_M05687)

NCS:	NCAS_0D04140(NCAS0D04140)

NDI:	NDAI_0I00780(NDAI0I00780)

TPF:	TPHA_0J02410(TPHA0J02410)

TBL:	TBLA_0B05350(TBLA0B05350)

TGB:	HG536_0E05370

TDL:	TDEL_0E05270(TDEL0E05270)

KAF:	KAFR_0K02320(KAFR0K02320)

KNG:	KNAG_0F01940(KNAG0F01940)

ZMK:	HG535_0B00870

SLUD:

SCDLUD_001106

DHA:	DEHA2C04158g

PIC:	PICST_89290(ALG2)

PGU:	PGUG_05778

SPAA:

SPAPADRAFT_52552

LEL:	PVL30_005586(ALG2)

LBG:	92209344(LODBEIA_P41480)

CAL:	CAALFM_C604030WA(ALG2)

CTP:	CTRG_02748

COT:	CORT_0F02370

CDU:	CD36_64500

CLU:	CLUG_05086

CLUS:

A9F13_03g01507

CAUR:

CJI96_0002247

PPA:	PAS_c121_0002

PKZ:	C5L36_0B10400

BNN:	FOA43_001034

BBRX:

BRETT_003668

OPA:	HPODL_04618

YLI:	2911827(YALI2_F00408g)

SLB:	AWJ20_2865(ALG2)

NCR:	NCU03503(cot-5)

NTE:	NEUTE1DRAFT66075(NEUTE1DRAFT_66075)

SMP:	10801970(SMAC4_07237)

PAN:	PODANSg6988

PBEL:

QC761_604530(ALG2)

PPSD:

QC762_604530(ALG2)

PPSP:

QC763_604530(ALG2)

PPSA:

QC764_604530(ALG2)

TTT:	THITE_2123138

MTM:	MYCTH_2311469

CTHR:

CTHT_0007110

MGR:

MGG_02384

PPEI:

PpBr36_06957

PGRI:

PgNI_05521

TMN:	UCRPA7_8209

SSCK:

SPSK_04214

FGR:	FGSG_01640

FPU:	FPSE_09750

FPOA:

FPOAC1_001764

FVN:	FVRRES_01978

FVR:	FVEG_09738

FOX:	FOXG_11063

NHE:	NECHADRAFT_30261

FFC:	NCS54_00018000

FKR:	NCS57_00015800

FMU:	J7337_000228(ALG2)

TRE:	TRIREDRAFT_70035

TRR:	M419DRAFT_91331

TATV:

25786616(TrAtP1_009364)

TASP:

36610913(ALG2)

MAW:	19250104(ALG2_1)

MAJ:

MAA_08596

MBRN:

26243939(alg-2)

PCHM:

VFPPC_02331

CMT:

CCM_02067

AMUS:

LMH87_003228

PLJ:	28889527(PLICBS_008045)

PTKZ:

JDV02_010414(ALG2)

VAL:	VDBG_05501

VDA:	VDAG_07149

CFJ:	CFIO01_09218

CLUP:

CLUP02_02131

CHIG:

CH63R_10845

CDET:

87943926(CDEST_07423)

SAPO:

SAPIO_CDS1116

ELA:	UCREL1_2618

PFY:	PFICI_09278

SSL:	SS1G_02473

BFU:	BCIN_13g03800(Bcalg2)

MBE:

MBM_06396

PSCO:

LY89DRAFT_574121

GLZ:	GLAREA_11972

ANI:	ANIA_06874

AFM:	AFUA_5G13210

ACT:	ACLA_016180

NFI:	NFIA_073820

AOR:	AO090120000461

ANG:	An14g05910

AFV:	AFLA_009672

ALUC:

AKAW2_41216A(ALG2)

ACHE:

ACHE_51149S(ALG2)

APUU:

APUU_12187A(ALG2)

PCS:	N7525_007262

PDP:	PDIP_59020

POU:	POX_d05437

TMF:	EYB26_002069

TRG:	TRUGW13939_05210

CIM:	CIMG_09741

CPW:	CPC735_023190

URE:	UREG_04663

ABE:

ARB_02714

TVE:

TRV_05563

PBL:	PAAG_05192

PBN:	PADG_05063

AJE:	HCAG_00318

BGH:	BDBG_01580

PNO:	SNOG_14088

PTE:

PTT_03994

PTRR:

6347354(PtrM4_035490)

BZE:	COCCADRAFT_109937

BSC:	COCSADRAFT_32523

BOR:	COCMIDRAFT_81095

AALT:

CC77DRAFT_941333

ARAB:

EKO05_0009020

ZTR:	MYCGRDRAFT_75289(Mg61467)

PFJ:	MYCFIDRAFT_190600

FFU:	CLAFUR5_11566

CBET:

CB0940_07211

BCOM:

BAUCODRAFT_311273

NPA:	UCRNP2_5009

TML:	GSTUM_00001241001

SPO:	2539854(alg2)

SOM:	SOMG_00908(alg2)

CNE:

CND00660

CNB:

CNBD5610

CNG:	CNAG_00926

CGI:	CGB_J1620C

CDEU:

CNBG_6038

CDEP:

91090189(L203_105981)

KMG:	30161903(I203_107345)

KNE:	92183177(IAR55_005919)

TMS:	TREMEDRAFT_74186 TREMEDRAFT_74187

TASA:

A1Q1_01692

CCAC:

CcaHIS019_0110670(ALG2)

TVS:	TRAVEDRAFT_46179

DSQ:	DICSQDRAFT_146404

PCO:	PHACADRAFT_122257

SHS:	STEHIDRAFT_84779

HIR:	HETIRDRAFT_146079

PSQ:	PUNSTDRAFT_70194

ADL:	AURDEDRAFT_80935

GTR:	GLOTRDRAFT_141423

RSX:	RhiXN_01473

LBC:	LACBIDRAFT_247825(ALG2)

CCI:	CC1G_04804

ABP:	AGABI1DRAFT125635(AGABI1DRAFT_125635)

ABV:	AGABI2DRAFT65105(AGABI2DRAFT_65105)

PCUB:

JR316_0003588

MPR:	MPER_07727

MRR:	Moror_12356

E1B28_007837

SCM:	SCHCO_02630867(SCHCODRAFT_02630867)

CPUT:

CONPUDRAFT_118510

SLA:	SERLADRAFT_474957

WSE:	WALSEDRAFT_59654

WIC:	J056_002368

UMA:	UMAG_02653

PFP:	PFL1_03826

SGRA:

EX895_005306

MGL:

MGL_1050

MRT:

MRET_3105

MSYM:

MSY001_0809(ALG2)

PGR:	PGTG_20272 PGTG_21912

PTRC:

PtA15_10A663

PSTR:

Pst134EA_030169 Pst134EA_031626

MLR:	MELLADRAFT_42497

RIE:	OCT59_005217

SRE:	PTSG_07164

DDI:	DDB_G0272730(alg2)

DPP:	DICPUDRAFT_88372

DFA:	DFA_05987(alg2)

EHI:	EHI_001990(90.t00023) EHI_162230

EDI:	EDI_074330 EDI_138820

EIV:	EIN_313420

ACAN:

ACA1_360020

CPV:

cgd1_230

CHO:	Chro.10033

TGO:	TGME49_227790

BBES:

BESB_059160

TET:	TTHERM_00335960

PTM:	GSPATT00017608001

PTI:	PHATRDRAFT_22554

FCY:	FRACYDRAFT_158588

TPS:	THAPS_263193

NGD:	NGA_2082800(ALG2)

AAF:	AURANDRAFT_29980

SPAR:

SPRG_01564

GTT:	GUITHDRAFT_74012

TBR:	Tb927.4.2230

TBG:	TbgDal_IV2190

TCR:	506559.420

LMA:	LMJF_34_2420

LIF:	LINJ_34_2190

LDO:	LDBPK_342190

LMI:	LMXM_33_2420

LBZ:	LBRM_20_1920

LPAN:

LPMP_202100

LOI:	92356968(LSCM4_00968)

LEIS:

94177506(GH5_01956)

LENR:

94168809(CUR178_01530)

LEIN:

94185308(JIQ42_01569)

PHET:

94287931(JKF63_01808)

NGR:	NAEGRDRAFT_32499

TVA:	TVAG_2v0348080

WBA:	UR17_C0001G0513(alg2)

» show all

Reference

1 [PMID:19282279]

Authors

Kampf M, Absmanner B, Schwarz M, Lehle L

Title

Biochemical characterization and membrane topology of Alg2 from Saccharomyces cerevisiae as a bifunctional alpha1,3- and 1,6-mannosyltransferase involved in lipid-linked oligosaccharide biosynthesis.

Journal

J Biol Chem 284:11900-12 (2009)
DOI:10.1074/jbc.M806416200

Reference

2 [PMID:16878994]

Authors

O'Reilly MK, Zhang G, Imperiali B.

Title

In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis.

Journal

Biochemistry 45:9593-603 (2006)
DOI:10.1021/bi060878o

Sequence

[sce:YGL065C]