KEGG   ENZYME: 2.4.1.260
Entry
EC 2.4.1.260                Enzyme                                 
Name
dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase;
ALG12;
ALG12 mannosyltransferase;
ALG12 alpha1,6mannosyltransferase;
dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl mannosyltransferase;
dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl alpha6-mannosyltransferase;
EBS4;
Dol-P-Man:Man7GlcNAc2-PP-Dol alpha-1,6-mannosyltransferase;
dolichyl beta-D-mannosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,6-mannosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
dolichyl beta-D-mannosyl-phosphate:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-beta-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol 6-alpha-D-mannosyltransferase (configuration-inverting)
Reaction(IUBMB)
dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-beta-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol = alpha-D-Man-alpha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + dolichyl phosphate [RN:R06260]
Reaction(KEGG)
R06260(G)
Substrate
dolichyl beta-D-mannosyl phosphate [CPD:C03862];
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-beta-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol
Product
alpha-D-Man-alpha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol;
dolichyl phosphate [CPD:C00110]
Comment
The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl diphosphate. Early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9Glc-NAc2-PP-Dol on the lumenal side use dolichyl beta-D-mannosyl phosphate.
History
EC 2.4.1.260 created 1976 as EC 2.4.1.130, part transferred 2011 to EC 2.4.1.160, modified 2012
Pathway
ec00510  N-Glycan biosynthesis
ec00513  Various types of N-glycan biosynthesis
ec01100  Metabolic pathways
Orthology
K03847  alpha-1,6-mannosyltransferase
Genes
HSA: 79087(ALG12)
PTR: 470247(ALG12)
PPS: 100977641(ALG12)
GGO: 101126908(ALG12)
PON: 100431368(ALG12)
PPYG: 129023185(ALG12)
NLE: 100588258(ALG12)
HMH: 116458227(ALG12)
SSYN: 129468413(ALG12)
MCC: 715172(ALG12)
MCF: 102117563(ALG12)
MTHB: 126929458
MNI: 105489769(ALG12)
CSAB: 103223543(ALG12)
CATY: 105586894(ALG12)
PANU: 101025888(ALG12)
TGE: 112633486(ALG12)
MLEU: 105543608(ALG12)
RRO: 104670360(ALG12)
RBB: 108516534(ALG12)
TFN: 117096285(ALG12)
PTEH: 111549098(ALG12)
CANG: 105511996(ALG12)
CJC: 100392255(ALG12)
SBQ: 101036432(ALG12)
CIMI: 108286805
ANAN: 105704881(ALG12)
CSYR: 103255319(ALG12)
MMUR: 105885030(ALG12)
LCAT: 123640778(ALG12)
PCOQ: 105813921(ALG12)
OGA: 100966838(ALG12)
MMU: 223774(Alg12)
MCAL: 110310083(Alg12)
MPAH: 110334975(Alg12)
RNO: 315212(Alg12)
MCOC: 116077624(Alg12)
ANU: 117718595(Alg12)
MUN: 110549675(Alg12)
CGE: 100770096(Alg12)
MAUA: 101830842(Alg12)
PROB: 127225929(Alg12)
PLEU: 114699216(Alg12)
MORG: 121461007(Alg12)
MFOT: 126493138
AAMP: 119822329(Alg12)
NGI: 103735462(Alg12)
HGL: 101715432(Alg12)
CPOC: 100722302(Alg12)
CCAN: 109697709(Alg12)
DORD: 105992753(Alg12)
DSP: 122123645(Alg12)
PLOP: 125357118(Alg12)
NCAR: 124982111
MMMA: 107160235(Alg12)
ITI: 101957373(Alg12)
OCU: 100346344
OPI: 101529961(ALG12)
TUP: 102492059(ALG12)
GVR: 103587485(ALG12)
CFA: 481196(ALG12)
CLUD: 112665819(ALG12)
VVP: 112935830(ALG12)
VLG: 121491169(ALG12) 121497486
NPO: 129511405(ALG12)
AML: 100477708(ALG12)
UMR: 103674123(ALG12)
UAR: 123803790(ALG12)
ELK: 111157563
LLV: 125106489
MPUF: 101676994(ALG12)
MNP: 132019100(ALG12)
MLK: 131839639(ALG12)
NVS: 122891398(ALG12)
ORO: 101363058(ALG12)
EJU: 114218378(ALG12)
ZCA: 113921767(ALG12)
MLX: 117997755(ALG12) 118012103
NSU: 110578299(ALG12)
LWW: 102727206(ALG12)
FCA: 101099567(ALG12)
PYU: 121040139(ALG12)
PCOO: 112863393(ALG12)
PBG: 122472969(ALG12)
PVIV: 125170127(ALG12)
LRUF: 124501725
LGF: 123590589(ALG12)
AJU: 106987628
PPAD: 109265747(ALG12)
PUC: 125919729
PLEZ: 122225276(ALG12)
HHV: 120233734(ALG12)
BTA: 100125314(ALG12)
BOM: 102281651(ALG12)
BBUB: 102403805(ALG12)
BBIS: 104982684(ALG12)
CHX: 102181760(ALG12)
OAS: 101112896(ALG12)
BTAX: 128047674(ALG12)
CSUM: 138078321(ALG12)
ODA: 120857818(ALG12)
CCAD: 122423526(ALG12)
MREE: 136175340(ALG12)
OVR: 110130218(ALG12)
MBEZ: 129536448(ALG12)
SSC: 100520494(ALG12)
CFR: 102524349(ALG12)
CBAI: 105070796(ALG12)
CDK: 105090366(ALG12)
VPC: 102526385(ALG12)
BACU: 103004635(ALG12)
BMUS: 118901775(ALG12)
LVE: 103079764(ALG12)
OOR: 101285549(ALG12)
LALB: 132529672(ALG12)
DLE: 111186266(ALG12)
PCAD: 102975935(ALG12)
PSIU: 116760259(ALG12)
PPHC: 136131066(ALG12)
NASI: 112394667(ALG12)
ECB: 100146652(ALG12)
EPZ: 103565594(ALG12)
EAI: 106845994(ALG12)
MYB: 102251651(ALG12)
MYD: 102767133(ALG12)
MMYO: 118657377(ALG12)
MLF: 102434071(ALG12)
MDT: 132226856(ALG12)
MYUM: 139005822(ALG12)
PKL: 118714726(ALG12)
EFUS: 103298647(ALG12)
MNA: 107536069(ALG12)
DRO: 112321642(ALG12)
SHON: 118989148(ALG12)
AJM: 119060267(ALG12)
PDIC: 114513325(ALG12)
PHAS: 123816086(ALG12)
MMF: 118641182(ALG12)
PPAM: 129077903(ALG12)
HAI: 109396645(ALG12)
RFQ: 117028108(ALG12)
PALE: 102883747(ALG12)
PGIG: 120602849(ALG12)
PVP: 105303067(ALG12)
RAY: 107500277(ALG12)
MJV: 108401703(ALG12)
TOD: 119247142(ALG12)
SARA: 101542405(ALG12)
SFUM: 130016401(ALG12)
SETR: 126006236(ALG12)
LAV: 100661791(ALG12)
TMU: 101345042
ETF: 101658231(ALG12)
DNM: 101417420(ALG12)
GAS: 123248656(ALG12)
SHR: 100920134(ALG12)
AFZ: 127538892
PCW: 110205944(ALG12)
TVP: 118852439(ALG12)
PBRV: 138170823(ALG12)
OAA: 100073873(ALG12)
TACU: 119937244(ALG12)
GGA: 417733(ALG12)
PCOC: 116243510(ALG12)
MGP: 100538714(ALG12)
CJO: 107308331(ALG12)
TPAI: 128073679(ALG12)
LMUT: 125691108(ALG12)
NMEL: 110392463(ALG12)
APLA: 101790290(ALG12)
ACYG: 106040489(ALG12)
CATA: 118254294(ALG12)
AFUL: 116487132(ALG12)
TGU: 100228059(ALG12)
LSR: 110484518(ALG12)
SCAN: 103813496(ALG12)
PMOA: 120510722(ALG12)
OTC: 121336391(ALG12)
PRUF: 121365725(ALG12)
ATRC: 139588451(ALG12)
GFR: 102041702(ALG12)
FAB: 101811748(ALG12)
OMA: 130266846(ALG12)
PHI: 102108073(ALG12)
PMAJ: 107204336(ALG12)
CCAE: 111923041(ALG12)
CCW: 104686842(ALG12)
CBRC: 103623441(ALG12)
ACOE: 138098804(ALG12)
ETL: 114060230(ALG12)
ZAB: 102060913(ALG12)
ZLE: 135442691(ALG12)
ACHL: 103798737(ALG12)
SVG: 106848792(ALG12)
MMEA: 130581085(ALG12)
HRT: 120752352(ALG12)
SATI: 136360994(ALG12)
CCIC: 134043878(ALG12)
FPG: 101921937(ALG12)
FCH: 102049527(ALG12)
CCRI: 104164255(ALG12)
NNT: 104403864(ALG12)
SHAB: 115605843(ALG12)
ACUN: 113491358(ALG12)
TALA: 104361818(ALG12)
ACHC: 115342306(ALG12)
HALD: 104311090(ALG12)
HLE: 104840129(ALG12)
AGEN: 126044318
HHAR: 128143032(ALG12)
GCL: 127023772
CSTI: 104556137(ALG12)
LDI: 104352945(ALG12)
MNB: 103769297(ALG12)
DPUB: 104308080(ALG12)
PPUS: 135174837(ALG12)
AVIT: 104267597(ALG12)
BRHI: 104501772(ALG12)
EGZ: 104134412(ALG12)
NNI: 104010710(ALG12)
PCRI: 104032009(ALG12)
PCAO: 104040992(ALG12)
PADL: 103912493(ALG12)
AFOR: 103908526(ALG12)
FGA: 104078602(ALG12)
GSTE: 104264077(ALG12)
CBOY: 140651235(ALG12)
CLV: 102086330(ALG12)
CNIC: 136002065(ALG12)
MUI: 104534574(ALG12)
PGUU: 104466996(ALG12)
PLET: 104614394(ALG12)
EHS: 104504277(ALG12)
CMAC: 104482033(ALG12)
CUCA: 104055274(ALG12)
TEO: 104378714(ALG12)
BREG: 104630375
OHA: 104337334(ALG12)
ACAR: 104529647(ALG12)
CPEA: 104390337(ALG12)
CVF: 104285221(ALG12)
RTD: 128911648(ALG12)
CRID: 134510273(ALG12)
AAM: 106495380(ALG12)
AROW: 112968148(ALG12)
NPD: 112959725(ALG12)
TGT: 104568650(ALG12)
DNE: 112990919(ALG12)
SCAM: 104139589(ALG12)
ASN: 102370274(ALG12)
AMJ: 102563831(ALG12)
CPOO: 109315679(ALG12)
GGN: 109292099(ALG12)
PSS: 102447329(ALG12)
CMY: 102931282(ALG12)
CCAY: 125630377(ALG12)
DCC: 119862481(ALG12)
CPIC: 101946366(ALG12)
TST: 117875810(ALG12)
CABI: 116822544(ALG12)
MRV: 120390892(ALG12)
ACS: 100560474(alg12)
ASAO: 132776307(ALG12)
PVT: 110076228(ALG12)
SUND: 121930865(ALG12)
PBI: 103051026(ALG12)
PMUR: 107289329(ALG12)
CTIG: 120308015(ALG12)
TSR: 106553630(ALG12)
PGUT: 117667488(ALG12)
APRI: 131202508(ALG12)
PTEX: 113445074(ALG12)
NSS: 113413025(ALG12)
VKO: 123020080(ALG12)
PMUA: 114605130(ALG12)
PRAF: 128422187(ALG12)
ZVI: 118091452(ALG12) 118091486
HCG: 128327052(ALG12)
GJA: 107112025(ALG12)
STOW: 125434375(ALG12)
EMC: 129335781(ALG12)
XLA: 108711164(alg12.L)
XTR: 548874(alg12)
NPR: 108796727(ALG12)
RTEM: 120931812(ALG12)
ACAT: 141131910(ALG12)
BBUF: 120982181(ALG12)
BGAR: 122927909(ALG12)
DTC: 141087725(ALG12)
PWL: 138288284(ALG12)
MUO: 115478416(ALG12)
GSH: 117366645(ALG12)
DRE: 569494(alg12)
SRX: 107730685(alg12)
SANH: 107699370(alg12)
SGH: 107601012(alg12)
CCAR: 109088012(alg12)
CAUA: 113062033(alg12)
CGIB: 127956944
PTET: 122335470 122342622(alg12)
LROH: 127164032(alg12)
GRF: 141333803(alg12)
OMC: 131539026(alg12)
PPRM: 120470641(alg12)
RKG: 130092507(alg12)
MAMB: 125244758(alg12)
CIDE: 127510562
CERY: 137024625(alg12)
MASI: 127435332
TROS: 130551367(alg12)
TDW: 130420275(alg12)
MANU: 129432481(alg12)
PDAB: 135745059(alg12)
IPU: 108279802
IFU: 128623580(alg12)
PHYP: 113532285(alg12)
SMEO: 124400835(alg12)
TFD: 113645776(alg12)
TVC: 132858731(alg12)
CGAR: 128533973(alg12)
NGRA: 132869721(alg12)
TRN: 134315790(alg12)
AMEX: 103044448(alg12)
CMAO: 118812390(alg12)
EEE: 113573577(alg12)
CHAR: 122130912(alg12)
SPIL: 134062605(alg12)
TRU: 101076670(alg12)
TFS: 130518925(alg12)
LCO: 104926575(alg12)
NCC: 104953716(alg12)
TBEN: 117483081(alg12)
CGOB: 115028430(alg12)
PGEO: 117468261(alg12)
GACU: 117558267(alg12)
EMAC: 134878874(alg12)
ELY: 117249287(alg12)
EFO: 125882758(alg12)
PLEP: 121961146(alg12)
SLUC: 116039834(alg12)
ECRA: 117939015(alg12)
ESP: 116673047(alg12)
GAT: 120817156(alg12)
PPUG: 119210230(alg12)
AFB: 129112223(alg12)
CLUM: 117726310(alg12)
PSWI: 130200893(alg12)
CANA: 137791262(alg12)
CVE: 137877169(alg12)
MSAM: 119918384(alg12)
SCHU: 122870927(alg12)
CUD: 121505529(alg12)
SPUL: 138599647(alg12)
LMIX: 132956757(alg12)
ALAT: 119032691(alg12)
ASTR: 137589060(alg12)
MZE: 101476903(alg12)
ONL: 100702718(alg12)
OAU: 116334940(alg12)
OLA: 101171875(alg12)
OML: 112153250(alg12)
CSAI: 133424593(alg12)
XMA: 102222592(alg12)
XCO: 114160906(alg12)
XHE: 116736399(alg12)
PRET: 108165888(alg12)
PLAI: 106948934(alg12)
PMEI: 106916605(alg12)
GAF: 122826702(alg12)
PPRL: 129376166(alg12)
CVG: 107094556(alg12)
CTUL: 119776230(alg12)
GMU: 124883390(alg12)
NFU: 107383916(alg12)
KMR: 108240986(alg12)
ALIM: 106521807(alg12)
NWH: 119428033(alg12)
AOCE: 111565703(alg12)
EJA: 138202677(alg12)
BFRE: 138621913(alg12)
MCEP: 125000187(alg12)
CSEM: 103382918(alg12)
POV: 109632793(alg12)
SSEN: 122766437(alg12)
SSOE: 131456929(alg12)
HHIP: 117757271(alg12)
HSP: 118101401(alg12)
PPLT: 128429085(alg12)
SMAU: 118317829(alg12)
LCF: 108899853
SDU: 111224930(alg12)
SLAL: 111651992(alg12)
XGL: 120798037(alg12)
HCQ: 109523664(alg12)
SSCV: 125992379(alg12)
SBIA: 133493548(alg12)
PEE: 133396895(alg12)
PTAO: 133471699(alg12)
BPEC: 110161826(alg12)
ENY: 140368135(alg12)
MALB: 109960949(alg12)
BSPL: 114861967(alg12)
SJO: 128385212(alg12)
SSCO: 134004315(alg12)
GMH: 115532029(alg12)
SASA: 100195409(alg12) 106609155
STRU: 115180311
OTW: 112216768(alg12)
OMY: 110490157(alg12)
OGO: 123994733(alg12)
ONE: 115106856(alg12)
OKI: 109864395(alg12)
OKE: 118366103(alg12)
OMM: 135514698(alg12)
OCLA: 139392750
SALP: 111951472(alg12)
SNH: 120031914(alg12)
CCLU: 121555199 121581251
ELS: 105020252(alg12)
OEP: 134037705(alg12)
SFM: 108931614(alg12)
PKI: 111853381(alg12)
AANG: 118219378(alg12)
AROT: 135245856(alg12)
CCOG: 133119091(alg12)
LOC: 102691088(alg12)
PSPA: 121319749(alg12)
ARUT: 117415153 117419504 117968879
PSEX: 120533937(alg12)
CMK: 103177032(alg12)
RTP: 109915320(alg12)
HOC: 132826899(alg12)
LERI: 129707764(alg12)
HAKA: 140738699(alg12)
PMRN: 116951110(ALG12)
LRJ: 133356389(ALG12)
BFO: 118415924
BBEL: 109472143
CIN: 100177471
SCLV: 120335788
SPU: 591306
LPIC: 129255669
AJJ: 139961032
APLC: 110974150
ARUN: 117306795
AAMU: 139933851
AFIL: 140148462
AJC: 117107870
SKO: 100374699
PFLL: 139135283
DME: Dmel_CG8412(Alg12)
DER: 6552279
DSE: 6607047
DSI: Dsimw501_GD18643(Dsim_GD18643)
DYA: Dyak_GE25981
DAN: 6505681
DSR: 110191756
DPO: 4801513
DPE: 6587997
DMN: 108155365
DWI: 6646959
DGR: 6568493
DMO: Dmoj_GI22746
DAZ: 108618404
DNV: 108648979
DHE: 111602790
DVI: 6629887(Alg12)
CCAT: 101449681
BOD: 106617807
BDR: 105231065
RZE: 108378583
AOQ: 129236199
ALUD: 128855554
TDA: 119677131 119680826
MDE: 101900007
SCAC: 106093557
LCQ: 111690971
LSQ: 119601700
CVJ: 135963585(Alg12)
GFS: 119634679
ECOE: 129941217
CLON: 129608507
HIS: 119652389
AGA: 1272167
ACOZ: 120949342
AARA: 120905777
AMER: 121588697
ASTE: 118505208
AMAP: 126555958
AFUN: 125763089
AMOU: 128306684
AMRS: 128708849
AALI: 118458243
ACOS: 131268671
AAG: 5564018
AALB: 109428475 115260009
ASUA: 134207695
CQU: CpipJ_CPIJ009375
CPII: 120432219
CBRI: 134830028
CNS: 116338790
BCOO: 119069488
LLL: 129797253
AME: 724431
ACER: 108001285
ALAB: 122720236
ADR: 102680260
AFLR: 100862921
BIM: 105680192
BVK: 117237785
BVAN: 117166080
BHUN: 126874909
BTER: 105665616
BAFF: 126926025
BPYO: 122576964
BPAS: 132915229
FVI: 122535451
CCAL: 108623949
OBB: 114876027
OLG: 117609924
MGEN: 117228138
NMEA: 116426687
CGIG: 122398797
SOC: 105198677
MPHA: 105838989
AEC: 105151528
ACEP: 105625286
PBAR: 105425633
VEM: 105560245
COBS: 139108725(Alg12)
TLN: 139810646(Alg12)
HST: 105191684
DQU: 106743760
CFO: 105250907
FEX: 115243518
PMEC: 138936324(Alg12)
LHU: 105677564(Alg12)
PGC: 109854174
OBO: 105286193
PCF: 106788943
PFUC: 122516803
VPS: 122631077
VCRB: 124426056
VVE: 124951532
NVI: 100120808
CSOL: 105367648
TPRE: 106651852
LBD: 127281177
MDL: 103572453
CGLO: 123275086
DAM: 107046240
VCAN: 122408928
CCIN: 107263490
AROA: 105693520
TCA: 660266
TMOL: 138124269(Alg12)
DPA: 109534052
ESIM: 136411145(Alg12)
EFOR: 136345545
SOY: 115890667
AGRG: 126736639
ATD: 109601432 126264175
CSET: 123308684
HAXR: 123674449
AGB: 108909635
DVV: 126889631
NVL: 108569886
APLN: 108740479
PPYR: 116170268
OTU: 111415243
BMOR: 101745504
BMAN: 114250897
MSEX: 115450201
DPL: KGM_214579
BANY: 112044345
NIQ: 126775950
VCD: 124538668
MCIX: 123662376
PMAC: 106721445
PPOT: 106104341
PXU: 106120331
BPHI: 137919712(Alg12)
PRAP: 110993073
PBX: 123716345
PNAP: 125056080
ZCE: 119828467 119828764
CCRC: 123699772
LSIN: 126970240
AAGE: 121725972
HAW: 110382926
HZE: 124640124
TNL: 113498899
SLIU: 111350370
OFU: 114360779
ONU: 135080649
ATRA: 106136197
GMW: 113519697
PXY: 105392967
PGW: 126374981
LGLY: 125232413
CSTB: 134748601
CFUM: 141432754(Alg12) 141432998
CFEL: 113372891
CCRN: 123293393
API: 100160697
AGS: 114128596
RMD: 113556719
ACOO: 126844920
DVT: 126899734
BTAB: 109030158
DCI: 103519096 108252388
CLEC: 106666615
HHAL: 106685794(Alg12)
NLU: 111044467
MQU: 128982846 128983058
PHU: Phum_PHUM333940
ZNE: 110831686
PAME: 138699943(Alg12)
BROR: 134535867
IEL: 124167530
HAMR: 139693437 139696107(Alg12) 139698902
FCD: 110842961
DPX: DAPPUDRAFT_307223 DAPPUDRAFT_340335
DMK: 116929215
DPZ: 124328514 124340512
AFRA: 136028935
PJA: 122258463
PCHN: 125033412
PCLA: 123746266(Alg12)
CQD: 128702662(Alg12)
PTRU: 123510247
MNZ: 135215886
MRJ: 136843255(Alg12)
PORN: 139764323(Alg12)
HAZT: 108665558
LSM: 121121244(Alg12)
TCF: 131888816
PPOI: 119093282
ISC: 8037712
DSV: 119460564
RSAN: 119397066
RMP: 119175072
VDE: 111243282
VJA: 111265944
GOE: 100907023
TUT: 107359154
DPTE: 113795019
DFR: 124490814
CSCU: 111614632
CVS: 136981416(Alg12)
PTEP: 107438060
ABRU: 129966667
UDV: 129219920
SDM: 118192007
LPOL: 106457197
PMEO: 129584957
CEL: CELE_ZC513.5(algn-12)
CBR: CBG_11382
CRQ: GCK72_018739
NAI: NECAME_10496
BMY: BM_BM7406(Bm7406)
LOA: LOAG_16479
TSP: Tsp_15122
HRO: HELRODRAFT_70039
LGI: LOTGIDRAFT_228830
PVUL: 126826883
PCAN: 112567001
LSAX: 138958952
BGT: 106074820
GAE: 121390318
HRF: 124136036
HRJ: 124283281
HASI: 137295814
HCRA: 139445177
CRG: 105322567
CANU: 128158125
CVN: 111108038
OED: 125654018
MYI: 110454805
PMAX: 117331552
AIRR: 138336956
MCAF: 127727228
MMER: 123529376
RPHI: 132726907
DPOL: 127879898
MAEA: 128217956
OBI: 106867594
OSN: 115212963
LJP: 135471386
LAK: 106178263
SMM: Smp_161590
OVI: T265_07001
EGL: EGR_00931
LLON: 135491070
NVE: 5521096
EPA: 110245274
ATEN: 116306863
ADF: 107341875
AMIL: 114946922
MCAZ: 138056568 138056569
MFOO: 138011422
PDAM: 113684862
SPIS: 111339781
DGT: 114521801
XEN: 124434036
HMG: 100214068
HSY: 130613347
RES: 135693725
TAD: TRIADDRAFT_28195
AQU: 100640861
ATH: AT1G02145(ALG12)
ALY: 9328085
CRB: 17897192
CSAT: 104758180 104773533 104773734
EUS: EUTSA_v10007459mg
BRP: 103843832 103844697
BNA: 106370825 106400825 106426032 106434177
BOE: 106294422 106308420
RSZ: 108806148 108857290 130507983
THJ: 104814061
CPAP: 110816214
CIT: 102622888
CIC: CICLE_v10019843mg
PVY: 116135967
MINC: 123215301
TCC: 18614505
GRA: 105791709
GHI: 107900803 107929688
GAB: 108470165
HSYR: 120161313
DZI: 111313726
EGR: 104444420
RARG: 115726301
GMX: 100776070 100786127
GSJ: 114406490 114418815
PVU: 137818427
VRA: 106774197
VAR: 108347728
VUN: 114167535
VUM: 124826538
CCAJ: 109818826
APRC: 113849359
MTR: 25500106
TPRA: 123882973
CAM: 101509278
PSAT: 127076693
VVO: 131616108
LJA: 130737810 130748277
ADU: 107464448
AIP: 107618752
AHF: 112710211 112776335
LANG: 109352550
PCIN: 129289931 129291074
QSA: O6P43_017265
FVE: 101300391
AANS: 126803172
RCN: 112181879
PPER: 109947168
PMUM: 103331526
PAVI: 110745699
PDUL: 117619824
MDM: 103438967
MSYL: 126630549
PXB: 103964190
PCOX: 137734625
ZJU: 132803813
MNT: 21391423
CSAV: 115709948
CSV: 101222209
CMO: 103498998
BHJ: 120067141
MCHA: 111022781
CMAX: 111499003
CMOS: 111460074
CPEP: 111807199
RCU: 8263298
MEAN: 126686328
JCU: 105643234
HBR: 110635799
MESC: 110615915
POP: 7483803
PEU: 105120738
PALZ: 118042166
PNZ: 133690513
JRE: 109016718
CILL: 122292695
CAVE: 132179831
AGLU: 133880602
QLO: 115987320
TWL: 119984708
VVI: 100253051
VRI: 117932336
SLY: 101253423
SPEN: 107028308
SOT: 102579208
SSTN: 125845908
SDUL: 129886776
CANN: 107844599
LBB: 132645818
NTA: 107790560 107800663
NSY: 104216946
NTO: 104098178
NAU: 109224565
INI: 109155587
ITR: 115997343
SIND: 105169914
OEU: 111383370
EGT: 105954823
SSPL: 121775114 121802383 121808053
SMIL: 131022098
SHIS: 125197469 125200920
APAN: 127260890
HPUM: 140887045
PHUA: 140990941
HAN: 110922314
ECAD: 122595710
LSV: 111885666
CCAV: 112522500
DCR: 108202471
CSIN: 114276460
RVL: 131331826
AEW: 130783333
DLT: 127787412
BVG: 104905254
SOE: 110803939
CQI: 110720492 110721548
ATRI: 130810510
MOF: 131165720
NNU: 104589452
MING: 122084134
TSS: 122665382
PSOM: 113284616 113343855
OSA: 4336560
DOSA: Os04g0544900
OBR: 102708889
OGL: 127771267
BDI: 100830072
ATS: 109740842
TDC: 119355961 119365096
TAES: 123046208 123054085 123189971
TUA: 125531250
LPER: 127335802
LRD: 124676160 124677969
SBI: 8055942
ZMA: 100282442
MFLO: 136496835
SITA: 101755068
SVS: 117864492
PVIR: 120642645 120682558
PHAI: 112901344
PAUA: 133888265
PDA: 103704603
EGU: 105053932
MUS: 135627669
ZOF: 121969770 121974897
DCT: 110107771
PEQ: 110020637
AOF: 109839065
MSIN: 131234006
ACAK: 137934163
NCOL: 116252677
ATR: 18429228
CJF: 131036644 131073130
SMO: SELMODRAFT_91475(GT22A3)
PPP: 112295252
CSL: COCSUDRAFT_29611
CVR: CHLNCDRAFT_8393
APRO: F751_2283
OLU: OSTLU_43663
OTA: OT_ostta14g02510
BPG: Bathy13g00280
MIS: MICPUN_63738
MPP: MICPUCDRAFT_22710
GSL: Gasu_59850
CCP: CHC_T00009193001
SCE: YNR030W(ALG12)
SEUB: DI49_4762
SPAO: SPAR_N03310
AGO: AGOS_AAR043C
ERC: Ecym_2496
KLA: KLLA0_C08591g
KMX: KLMA_70199(ALG12)
LTH: KLTH0A06710g
VPO: Kpol_1028p42
ZRO: ZYRO0D08250g
CGR: 2891380(GVI51_M10747)
NCS: NCAS_0A05360(NCAS0A05360)
NDI: NDAI_0K02210(NDAI0K02210)
TPF: TPHA_0M01820(TPHA0M01820)
TBL: TBLA_0F04110(TBLA0F04110)
TGB: HG536_0A09110
TDL: TDEL_0A07530(TDEL0A07530)
KAF: KAFR_0C04580(KAFR0C04580)
KNG: KNAG_0D00400(KNAG0D00400)
ZMK: HG535_0A07420
SLUD: SCDLUD_003737
DHA: DEHA2C17270g
PIC: PICST_31100(ECM39)
PGU: PGUG_03898
SPAA: SPAPADRAFT_63472
LBG: 92211325(LODBEIA_P61290)
CAL: CAALFM_C702970WA(ECM39)
CTP: CTRG_05215
COT: CORT_0G04380
CDU: CD36_72630
CLU: CLUG_04302
CLUS: A9F13_04g02123
CAUR: CJI96_0003362
ASAU: 88172833(PUMCH_001768)
PPA: PAS_chr4_0544
PKZ: C5L36_0E01690
BNN: FOA43_004766
BBRX: BRETT_001636
YLI: 2909087(YALI2_C01162g)
SLB: AWJ20_3629(ALG12)
NCR: NCU07472
NTE: NEUTE1DRAFT88888(NEUTE1DRAFT_88888)
SMP: 10804390(SMAC4_05174)
PAN: PODANSg09956
PBEL: QC761_106880(ECM39)
PPSD: QC762_106880(ECM39)
PPSP: QC763_106880(ECM39)
PPSA: QC764_106880(ECM39)
TTT: THITE_21903
MTM: MYCTH_2295836
CTHR: CTHT_0053460
RTHE: 98123308(VTJ83DRAFT_2399)
MGR: MGG_09909
PPEI: PpBr36_07683
PGRI: PgNI_06318
TMN: UCRPA7_6503
SSCK: SPSK_08732
FGR: FGSG_01233
FPU: FPSE_01776
FPOA: FPOAC1_001325
FVN: FVRRES_01518
FVR: FVEG_01362
FOX: FOXG_00155
NHE: NECHADRAFT_105807
FFC: NCS54_00062000
FKR: NCS57_00060200
FMU: J7337_000660
TRE: TRIREDRAFT_63828
TRR: M419DRAFT_130862
TATV: 25786105(TrAtP1_003472)
TASP: 36612250(TrAFT101_007145)
MAW: 19244883(ECM39_1)
MAJ: MAA_07235
MBRN: 26240838(alg12)
PCHM: VFPPC_16459
CMT: CCM_06927
AMUS: LMH87_011648
PLJ: 28885504(PLICBS_007060)
PTKZ: JDV02_001673(ECM39)
VDA: VDAG_04507
CFJ: CFIO01_04924
CLUP: CLUP02_05288
CHIG: CH63R_00467
CDET: 87939173(CDEST_02670)
SAPO: SAPIO_CDS0782
ELA: UCREL1_7790
PFY: PFICI_01052
SSL: SS1G_10012
BFU: BCIN_07g04680
MBE: MBM_02529
PSCO: LY89DRAFT_604257
GLZ: GLAREA_00829
ANI: ANIA_03588
AFM: AFUA_4G12900
ACT: ACLA_051860
NFI: NFIA_103440
AOR: AO090009000318
ANG: An01g08460
AFV: AFLA_011040
ALUC: AKAW2_20899A(ALG12)
ACHE: ACHE_10334A(ALG12)
APUU: APUU_60284A(ALG12)
PCS: N7525_005919
PDP: PDIP_44640
POU: POX_a01606
TMF: EYB26_005179
TRG: TRUGW13939_02644
CIM: CIMG_00617
CPW: 9691884(ALG12)
URE: UREG_00622
ABE: ARB_00142
TVE: TRV_01650
PBL: PAAG_07032
PBN: PADG_01561
BGH: BDBG_16518
PNO: SNOG_04448
PTE: PTT_15141
PTRR: 6346218(PtrM4_136970)
BZE: COCCADRAFT_2870
BSC: COCSADRAFT_191517
BOR: COCMIDRAFT_98235
AALT: CC77DRAFT_933602
ADAC: 96086925(ACET3X_006603)
ARAB: EKO05_0002388
ZTR: MYCGRDRAFT_109480
PFJ: MYCFIDRAFT_34652
FFU: CLAFUR5_08542
CBET: CB0940_04748
BCOM: BAUCODRAFT_35286
NPA: UCRNP2_3478
SPO: 2540068(alg12)
SOM: SOMG_01385(alg12)
CNE: CNC03430
CNB: CNBC3790
CNG: CNAG_02715 CNAG_07527
CGI: CGB_C5280C
CDEU: CNBG_3379
CDEC: 89987967(IAS62_001192) 89991678(IAS62_004907)
CTEG: 91988882(I308_102024) 91992032(I308_105176)
CBAS: 91982075(I312_102027)
KMG: 30166778(I203_106539)
KNE: 92178344(IAR55_001085)
KDJ: 28964970(I303_101264)
KBI: 30207412(I302_104306)
KPIN: 30169516(I206_100179)
KSH: 87953210(IL334_001079)
KER: 91106333(V865_007532)
TMS: TREMEDRAFT_41756
TASA: A1Q1_05444
CCAC: CcaHIS019_0404510(ECM39)
TVS: TRAVEDRAFT_126346
PCO: PHACADRAFT_180449 PHACADRAFT_214615
SHS: STEHIDRAFT_165833 STEHIDRAFT_73504
HIR: HETIRDRAFT_165790
PSQ: PUNSTDRAFT_120292
ADL: AURDEDRAFT_143051
FME: FOMMEDRAFT_131787
GTR: GLOTRDRAFT_79634
RSX: RhiXN_02631 RhiXN_02632
LBC: LACBIDRAFT_302539(ALG12)
CCI: CC1G_11662
ABP: AGABI1DRAFT75475(AGABI1DRAFT_75475)
ABV: AGABI2DRAFT184199(AGABI2DRAFT_184199)
MRR: Moror_3413
MORE: E1B28_010872
SCM: SCHCO_02487496(SCHCODRAFT_02487496)
CPUT: CONPUDRAFT_151427
SLA: SERLADRAFT_467450
WSE: WALSEDRAFT_68580
WIC: J056_001199
UMA: UMAG_11341
PFP: PFL1_03512
SGRA: EX895_000567
MGL: MGL_2261
MRT: MRET_0251
MSYM: MSY001_1982(ALG12)
PGR: PGTG_03644
PTRC: PtA15_3A633
PSTR: Pst134EA_007111
MLR: MELLADRAFT_40792
RIE: OCT59_020250
MBR: MONBRDRAFT_31470
SRE: PTSG_11395
DDI: DDB_G0267884(alg12)
DPP: DICPUDRAFT_80121
DFA: DFA_08503(alg12)
PTI: PHATRDRAFT_44425
FCY: FRACYDRAFT_247580
TPS: THAPSDRAFT_262459
PIF: PITG_10838
PSOJ: PHYSODRAFT_469873
SPAR: SPRG_11694 SPRG_16521
TBR: Tb927.2.4720
TBG: TbgDal_II2750
TCR: 509317.50 511621.60
NGR: NAEGRDRAFT_29294
EHX: EMIHUDRAFT_454648
GTT: GUITHDRAFT_65500
 » show all
Reference
1  [PMID:15987956]
  Authors
Frank CG, Aebi M.
  Title
ALG9 mannosyltransferase is involved in two different steps of lipid-linked oligosaccharide biosynthesis.
  Journal
Glycobiology 15:1156-63 (2005)
DOI:10.1093/glycob/cwj002
  Sequence
[sce:YNR030W]
Reference
2  [PMID:20023196]
  Authors
Hong Z, Jin H, Fitchette AC, Xia Y, Monk AM, Faye L, Li J
  Title
Mutations of an alpha1,6 mannosyltransferase inhibit endoplasmic reticulum-associated degradation of defective brassinosteroid receptors in Arabidopsis.
  Journal
Plant Cell 21:3792-802 (2009)
DOI:10.1105/tpc.109.070284
  Sequence
[ath:AT1G02145]
Reference
3  [PMID:12460943]
  Authors
Cipollo JF, Trimble RB
  Title
The Saccharomyces cerevisiae alg12delta mutant reveals a role for the middle-arm  alpha1,2Man- and upper-arm alpha1,2Manalpha1,6Man- residues of Glc3Man9GlcNAc2-PP-Dol in regulating glycoprotein glycan processing in the endoplasmic reticulum and Golgi apparatus.
  Journal
Glycobiology 12:749-62 (2002)
DOI:10.1093/glycob/cwf082
Reference
4  [PMID:12217961]
  Authors
Grubenmann CE, Frank CG, Kjaergaard S, Berger EG, Aebi M, Hennet T
  Title
ALG12 mannosyltransferase defect in congenital disorder of glycosylation type lg.
  Journal
Hum Mol Genet 11:2331-9 (2002)
DOI:10.1093/hmg/11.19.2331
  Sequence
[hsa:79087]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.260
IUBMB Enzyme Nomenclature: 2.4.1.260
ExPASy - ENZYME nomenclature database: 2.4.1.260
BRENDA, the Enzyme Database: 2.4.1.260

  All links  
Gene (1990)   
   MGENES (460)   
   RefGene (1530)   
Protein sequence (52)   
   UniProt (10)   
   SWISS-PROT (7)   
   RefSeq(pep) (35)   
DNA sequence (120)   
   RefSeq(nuc) (58)   
   GenBank (32)   
   EMBL (30)   
Protein domain (1)   
   InterPro (1)   
All databases (2163)   

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