KEGG   ENZYME: 2.4.1.286Help
Entry
EC 2.4.1.286                Enzyme                                 

Name
chalcone 4'-O-glucosyltransferase;
4'CGT
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucosyltransferase
Reaction(IUBMB)
(1) UDP-alpha-D-glucose + naringenin chalcone = UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside [RN:R08006];
(2) UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone = UDP + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside [RN:R08007]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:C00029];
naringenin chalcone [CPD:C06561];
2',3,4,4',6'-pentahydroxychalcone [CPD:C15525]
Product
UDP [CPD:C00015];
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside [CPD:C16407];
2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside [CPD:C16408]
Comment
Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers.
History
EC 2.4.1.286 created 2012
Orthology
K21372  chalcone 4'-O-glucosyltransferase
Reference
1  [PMID:16832053]
  Authors
Ono E, Fukuchi-Mizutani M, Nakamura N, Fukui Y, Yonekura-Sakakibara K, Yamaguchi M, Nakayama T, Tanaka T, Kusumi T, Tanaka Y.
  Title
Yellow flowers generated by expression of the aurone biosynthetic pathway.
  Journal
Proc Natl Acad Sci U S A 103:11075-80 (2006)
DOI:10.1073/pnas.0604246103
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.286
IUBMB Enzyme Nomenclature: 2.4.1.286
ExPASy - ENZYME nomenclature database: 2.4.1.286
BRENDA, the Enzyme Database: 2.4.1.286

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