KEGG   ENZYME: 2.4.1.29Help
Entry
EC 2.4.1.29                 Enzyme                                 

Name
cellulose synthase (GDP-forming);
cellulose synthase (guanosine diphosphate-forming);
cellulose synthetase;
guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase;
guanosine diphosphoglucose-cellulose glucosyltransferase;
GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
GDP-alpha-D-glucose:(1->4)-beta-D-glucan 4-beta-D-glucosyltransferase (configuration-inverting)
Reaction(IUBMB)
GDP-alpha-D-glucose + [(1->4)-beta-D-glucosyl]n = GDP + [(1->4)-beta-D-glucosyl]n+1 [RN:R02890 R06030]
Reaction(KEGG)
Substrate
GDP-alpha-D-glucose [CPD:C00394];
[(1->4)-beta-D-glucosyl]n
Product
GDP [CPD:C00035];
[(1->4)-beta-D-glucosyl]n+1
Comment
Involved in the synthesis of cellulose. A similar enzyme [EC 2.4.1.12, cellulose synthase (UDP-forming)] utilizes UDP-alpha-D-glucose.
History
EC 2.4.1.29 created 1965
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:4317490]
  Authors
Chambers J, Elbein AD.
  Title
Biosynthesis of glucans in mung bean seedlings. Formation of beta-(1,4)-glucans from GDP-glucose and beta-(1,3)-glucans from UDP-glucose.
  Journal
Arch Biochem Biophys 138:620-31 (1970)
DOI:10.1016/0003-9861(70)90389-9
Reference
2  [PMID:5824571]
  Authors
Flowers HM, Batra KK, Kemp J, Hassid WZ.
  Title
Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus and Lupinus albus.
  Journal
J Biol Chem 244:4969-74 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.29
IUBMB Enzyme Nomenclature: 2.4.1.29
ExPASy - ENZYME nomenclature database: 2.4.1.29
BRENDA, the Enzyme Database: 2.4.1.29
CAS: 9027-18-3

DBGET integrated database retrieval system