KEGG   ENZYME: 2.4.1.291
Entry
EC 2.4.1.291                Enzyme                                 
Name
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase;
PglJ
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-alpha-D-galactosamine:N-acetylgalactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol 3-alpha-N-acetyl-D-galactosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol = UDP + N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Product
UDP [CPD:C00015];
N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.291 created 2012
Orthology
K17248  N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase
Genes
CJE: Cj1127c(pglJ)
CJB: BN148_1127c(pglJ)
CJJ: CJJ81176_1144(pglJ)
CJU: C8J_1067(pglJ)
CJN: ICDCCJ07001_1084
CJI: CJSA_1069(pglJ)
CJM: CJM1_1105(pglJ)
CJS: CJS3_1173(pglJ)
CJP: A911_05460
CJEJ: N564_01095
CJEU: N565_01138
CJEN: N755_01131
CJEI: N135_01164
CJER: H730_06605
CJV: MTVDSCj20_1130(pglJ)
CJY: QZ67_01205(pglJ)
CJQ: UC78_1084(pglJ)
CJL: PJ17_05775
CJW: PJ18_05590
CJR: CJE1269(pglJ)
CJD: JJD26997_0594(pglJ)
CJZ: M635_01340
CJX: BN867_11180
CFF: CFF8240_1384
CFT: CFF04554_1399(pglJ)
CFV: CFVI03293_1422(pglJ)
CFX: CFV97608_1522(pglJ)
CFZ: CSG_15210
CAMP: CFT03427_1347(pglJ)
CFP: CR44_06815
CCV: CCV52592_1214(pglJ)
CHA: CHAB381_0955
CCO: CCC13826_0453(pglJ)
CCOC: CCON33237_1466(pglJ)
CLA: CLA_1252(pglJ)
CLR: UPTC16701_1235(pglJ)
CLM: UPTC16712_1253(pglJ)
CLQ: UPTC4110_1237(pglJ)
CLN: UPTC3659_1472(pglJ)
CLL: CONCH_1203(pglJ)
CCOL: BN865_10010
CCC: G157_03300
CCQ: N149_1068
CCF: YSQ_03335
CCY: YSS_06100
CCOI: YSU_03370
CCOF: VC76_05530(pglJ)
CCOO: ATE51_01350(pglJ)
CAJ: CIG1485E_1393(pglJ)
CIS: CINS_1217(pglJ)
CVO: CVOL_1231(pglJ)
CPEL: CPEL_1358(pglJ)
CAMR: CAQ16704_1263(pglJ)
CSM: CSUB8521_1439(pglJ)
CSF: CSUB8523_1535(pglJ)
CGRA: CGRAC_1491(pglJ)
CURE: CUREO_1375(pglJ)
CHYO: CHH_0376(pglJ)
CHV: CHELV3228_0553(pglJ)
CSPF: CSF_0894(pglJ)
CPIN: CPIN18020_0861(pglJ)
CCUN: CCUN_1170(pglJ)
CLX: CLAN_0353(pglJ)
CAVI: CAV_0410(pglJ)
CHW: A2J15_001345
CAMZ: CVIC12175_1315(pglJ)
CAMY: CSUIS_0198(pglJ)
COJ: CORN_1322(pglJ)
CUX: CUP3940_1138(pglJ)
CRX: CRECT_1677(pglJ)
CGEO: CGEO_1575(pglJ)
CCOR: CCORG_0292(pglJ)
CARM: CARM_1285(pglJ)
CMUC: CMCT_0315(pglJ)
CSHO: CSHOW_1519(pglJ)
CINF: CINF_0321(pglJ)
CNV: CNZW441b_1130(pglJ)
CVU: CVULP_0491(pglJ)
CDEV: CIGN_1244(pglJ)
CCAQ: CCAL_1420(pglJ)
FND: RF683_07685
ZLA: Q5W13_23525
ALUT: O5O44_09690
 » show all
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc Natl Acad Sci U S A 102:14255-9 (2005)
DOI:10.1073/pnas.0507311102
  Sequence
[cje:Cj1127c]
Reference
2  [PMID:18034500]
  Authors
Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B
  Title
Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway.
  Journal
Biochemistry 46:14342-8 (2007)
DOI:10.1021/bi701956x
  Sequence
[cje:Cj1127c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.291
IUBMB Enzyme Nomenclature: 2.4.1.291
ExPASy - ENZYME nomenclature database: 2.4.1.291
BRENDA, the Enzyme Database: 2.4.1.291

  All links  
Gene (84)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (83)   
Protein sequence (691)   
   UniProt (533)   
   SWISS-PROT (1)   
   RefSeq(pep) (157)   
DNA sequence (4627)   
   RefSeq(nuc) (3286)   
   GenBank (714)   
   EMBL (627)   
Protein domain (2)   
   InterPro (2)   
All databases (5404)   

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