KEGG   ENZYME: 2.4.1.291
Entry
EC 2.4.1.291                Enzyme                                 
Name
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase;
PglJ
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-alpha-D-galactosamine:N-acetylgalactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol 3-alpha-N-acetyl-D-galactosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol = UDP + N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Product
UDP [CPD:C00015];
N-acetyl-D-galactosaminyl-alpha-(1->4)-N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.291 created 2012
Orthology
K17248  N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase
Genes
CJE: Cj1127c(pglJ)
CJB: BN148_1127c(pglJ)
CJJ: CJJ81176_1144(pglJ)
CJU: C8J_1067(pglJ)
CJN: ICDCCJ07001_1084
CJI: CJSA_1069(pglJ)
CJM: CJM1_1105(pglJ)
CJS: CJS3_1173(pglJ)
CJP: A911_05460
CJEJ: N564_01095
CJEU: N565_01138
CJEN: N755_01131
CJEI: N135_01164
CJER: H730_06605
CJV: MTVDSCj20_1130(pglJ)
CJR: CJE1269(pglJ)
CJD: JJD26997_0594(pglJ)
CJZ: M635_01340
CJX: BN867_11180
CFF: CFF8240_1384
CFT: CFF04554_1399(pglJ)
CFV: CFVI03293_1422(pglJ)
CFX: CFV97608_1522(pglJ)
CAMP: CFT03427_1347(pglJ)
CFP: CR44_06815
CCV: CCV52592_1214(pglJ)
CHA: CHAB381_0955
CCO: CCC13826_0453(pglJ)
CCOC: CCON33237_1466(pglJ)
CLA: CLA_1252(pglJ)
CLR: UPTC16701_1235(pglJ)
CLM: UPTC16712_1253(pglJ)
CLQ: UPTC4110_1237(pglJ)
CLN: UPTC3659_1472(pglJ)
CLL: CONCH_1203(pglJ)
CCOL: BN865_10010
CCC: G157_03300
CCQ: N149_1068
CCF: YSQ_03335
CCY: YSS_06100
CCOI: YSU_03370
CAJ: CIG1485E_1393(pglJ)
CIS: CINS_1217(pglJ)
CVO: CVOL_1231(pglJ)
CPEL: CPEL_1358(pglJ)
CAMR: CAQ16704_1263(pglJ)
CSM: CSUB8521_1439(pglJ)
CSF: CSUB8523_1535(pglJ)
CURE: CUREO_1375(pglJ)
CAMZ: CVIC12175_1315(pglJ)
CMUC: CMCT_0315(pglJ)
CDEV: CIGN_1244(pglJ)
CCAQ: CCAL_1420(pglJ)
ZLA: Q5W13_23525
 » show all
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc Natl Acad Sci U S A 102:14255-9 (2005)
DOI:10.1073/pnas.0507311102
  Sequence
[cje:Cj1127c]
Reference
2  [PMID:18034500]
  Authors
Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B
  Title
Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway.
  Journal
Biochemistry 46:14342-8 (2007)
DOI:10.1021/bi701956x
  Sequence
[cje:Cj1127c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.291
IUBMB Enzyme Nomenclature: 2.4.1.291
ExPASy - ENZYME nomenclature database: 2.4.1.291
BRENDA, the Enzyme Database: 2.4.1.291

  All links  
Protein sequence (1288)   
   UniProt (403)   
   SWISS-PROT (1)   
   RefSeq(pep) (884)   
DNA sequence (8299)   
   RefSeq(nuc) (6832)   
   GenBank (758)   
   EMBL (709)   
All databases (9587)   

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