KEGG   ENZYME: 2.4.1.293Help
Entry
EC 2.4.1.293                Enzyme                                 

Name
GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase;
PglI
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:[GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol 3-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + [GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol = UDP  [GalNAc-alpha-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alpha-(1->4)]2-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Substrate
UDP-alpha-D-glucose [CPD:C00029];
[GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Product
UDP  [GalNAc-alpha-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alpha-(1->4)]2-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
Comment
Isolated from the bacterium Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.
History
EC 2.4.1.293 created 2012
Orthology
K17250  GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase
Genes
CJE: Cj1128c(pglI)
CJB: BN148_1128c(pglI)
CJJ: CJJ81176_1145(pglI)
CJU: C8J_1068(pglI)
CJN: ICDCCJ07001_1085
CJI: CJSA_1070(pgll)
CJM: CJM1_1106(pglI)
CJS: CJS3_1174(pglI)
CJP: A911_05465
CJEJ: N564_01096
CJEU: N565_01139
CJEN: N755_01132
CJEI: N135_01165
CJER: H730_06610
CJV: MTVDSCj20_1131(pglI)
CJY: QZ67_01206(pglI)
CJQ: UC78_1085(pglI)
CJR: CJE1270(pglI)
CJD: JJD26997_0593(pglI)
CCV: CCV52592_1217(pglI)
CCO: CCC13826_0456(pglI)
CCOC: CCON33237_1469(pglI)
CCQ: N149_1069
CCF: YSQ_03330
CCY: YSS_06105
CCOI: YSU_03365
CCOF: VC76_05535(pglI)
CCOO: ATE51_01348(pglI)
CHV: CHELV3228_0552(pglI)
CPIN: CPIN18020_0860(pglI)
CCUN: CCUN_1169(pglI)
TSH: Tsac_0593
BCEL: BcellWH2_05433(pglI_2)
CTHI: THC_1193
MMAC: MSMAC_0660
 » show all
Taxonomy
Reference
1  [PMID:16186480]
  Authors
Glover KJ, Weerapana E, Imperiali B
  Title
In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation.
  Journal
Proc Natl Acad Sci U S A 102:14255-9 (2005)
DOI:10.1073/pnas.0507311102
  Sequence
[cje:Cj1128c]
Reference
2  [PMID:16547029]
  Authors
Kelly J, Jarrell H, Millar L, Tessier L, Fiori LM, Lau PC, Allan B, Szymanski CM
  Title
Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer.
  Journal
J Bacteriol 188:2427-34 (2006)
DOI:10.1128/JB.188.7.2427-2434.2006
  Sequence
[cje:Cj1128c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.293
IUBMB Enzyme Nomenclature: 2.4.1.293
ExPASy - ENZYME nomenclature database: 2.4.1.293
BRENDA, the Enzyme Database: 2.4.1.293

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