KEGG   ENZYME: 2.4.1.298Help
Entry
EC 2.4.1.298                Enzyme                                 

Name
anthocyanidin 3-O-glucoside 5-O-glucosyltransferase;
UDP-glucose:anthocyanin 5-O-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:anthocyanidin-3-O-beta-D-glucoside 5-O-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + an anthocyanidin 3-O-beta-D-glucoside = UDP + an anthocyanidin 3,5-di-O-beta-D-glucoside [RN:R10262]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:C00029];
anthocyanidin 3-O-beta-D-glucoside [CPD:C15539]
Product
UDP [CPD:C00015];
anthocyanidin 3,5-di-O-beta-D-glucoside [CPD:C06361]
Comment
Isolated from the plants Perilla frutescens var. crispa, Verbena hybrida [1], Dahlia variabilis [2] and Gentiana triflora (clustered gentian) [3]. It will also act on anthocyanidin 3-O-(6-O-malonylglucoside) [2] and is much less active with hydroxycinnamoylglucose derivatives [3]. There is no activity in the absence of the 3-O-glucoside group.
History
EC 2.4.1.298 created 2013
Pathway
ec00942  Anthocyanin biosynthesis
Orthology
K12338  anthocyanidin 3-O-glucoside 5-O-glucosyltransferase
Genes
ATH: AT4G14090
ALY: ARALYDRAFT_915488
CRB: 17880057
EUS: EUTSA_v10025167mg
BRP: 103833789
BNA: 106397231
THJ: 104804785
Taxonomy
Reference
1  [PMID:10066805]
  Authors
Yamazaki M, Gong Z, Fukuchi-Mizutani M, Fukui Y, Tanaka Y, Kusumi T, Saito K
  Title
Molecular cloning and biochemical characterization of a novel anthocyanin 5-O-glucosyltransferase by mRNA differential display for plant forms regarding anthocyanin.
  Journal
J Biol Chem 274:7405-11 (1999)
DOI:10.1074/jbc.274.11.7405
  Sequence
Reference
2
  Authors
Ogata, J., Sakamoto, T., Yamaguchi, M., Kawanobu, S., Yoshitama, K.
  Title
Isolation and characterization of anthocyanin 5-O-glucosyltransferase from flowers of Dahlia variabilis.
  Journal
J Plant Physiol 158:709-714 (2001)
Reference
3  [PMID:18375606]
  Authors
Nakatsuka T, Sato K, Takahashi H, Yamamura S, Nishihara M
  Title
Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian.
  Journal
J Exp Bot 59:1241-52 (2008)
DOI:10.1093/jxb/ern031
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.298
IUBMB Enzyme Nomenclature: 2.4.1.298
ExPASy - ENZYME nomenclature database: 2.4.1.298
BRENDA, the Enzyme Database: 2.4.1.298

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