KEGG   ENZYME: 2.4.1.320Help
Entry
EC 2.4.1.320                Enzyme                                 

Name
1,4-beta-mannosyl-N-acetylglucosamine phosphorylase;
BT1033
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine:phosphate alpha-D-mannosyltransferase
Reaction(IUBMB)
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + phosphate = N-acetyl-D-glucosamine + alpha-D-mannose 1-phosphate [RN:R10829]
Reaction(KEGG)
Substrate
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine [CPD:C20887];
phosphate [CPD:C00009]
Product
N-acetyl-D-glucosamine [CPD:C00140];
alpha-D-mannose 1-phosphate [CPD:C00636]
Comment
The enzyme isolated from the anaerobic bacterium Bacteroides thetaiotaomicron is involved in the degradation of host-derived N-glycans.
History
EC 2.4.1.320 created 2014
Orthology
K18785  beta-1,4-mannooligosaccharide/beta-1,4-mannosyl-N-acetylglucosamine phosphorylase
Genes
VFU: vfu_B00533
VFL: AL536_06115
BCO: Bcell_1370
AXL: AXY_22380
GYM: GYMC10_2731 GYMC10_3409
PPY: PPE_04648
PPM: PPSC2_24185
PPO: PPM_4802(M1_5246)
PPOL: X809_40720
PPQ: PPSQR21_049000
PPOY: RE92_13090
CCE: Ccel_3001
CSD: Clst_1087
ESR: ES1_03380
ESU: EUS_01640
CCEL: CCDG5_2023
RCH: RUM_22240
FPA: FPR_17240
BHU: bhn_I1942
RIM: ROI_36350
COO: CCU_23030
CSC: Csac_0296
ATE: Athe_2555
TTM: Tthe_0138
TSH: Tsac_0695
HAU: Haur_0891
OTE: Oter_2313
BTH: BT_1033
BFR: BF1332
BVU: BVU_0612
PDI: BDI_0634
AFD: Alfi_2317
ASH: AL1_19480
DORI: FH5T_07110
MBAS: ALGA_4407
FLM: MY04_4859
FJO: Fjoh_2034
COC: Coch_0687
ZPR: ZPR_4182
EAO: BD94_2213
CHZ: CHSO_0298
MARF: CJ739_2385
TMA: TM1225
TMW: THMA_1251
TMQ: THMB_1251
TMX: THMC_1251
TPT: Tpet_1543
TRQ: TRQ2_1593
TNA: CTN_1346
TNP: Tnap_1567
TLE: Tlet_1437
TME: Tmel_1013
MARN: LN42_06120
DTU: Dtur_1800
 » show all
Taxonomy
Reference
1  [PMID:23943617]
  Authors
Nihira T, Suzuki E, Kitaoka M, Nishimoto M, Ohtsubo K, Nakai H
  Title
Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans.
  Journal
J Biol Chem 288:27366-74 (2013)
DOI:10.1074/jbc.M113.469080
  Sequence
[bth:BT_1033]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.320
IUBMB Enzyme Nomenclature: 2.4.1.320
ExPASy - ENZYME nomenclature database: 2.4.1.320
BRENDA, the Enzyme Database: 2.4.1.320

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