KEGG   ENZYME: 2.4.1.320
Entry
EC 2.4.1.320                Enzyme                                 
Name
1,4-beta-mannosyl-N-acetylglucosamine phosphorylase;
BT1033
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine:phosphate alpha-D-mannosyltransferase
Reaction(IUBMB)
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + phosphate = N-acetyl-D-glucosamine + alpha-D-mannose 1-phosphate [RN:R10829]
Reaction(KEGG)
R10829
Substrate
4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine [CPD:C20887];
phosphate [CPD:C00009]
Product
N-acetyl-D-glucosamine [CPD:C00140];
alpha-D-mannose 1-phosphate [CPD:C00636]
Comment
The enzyme isolated from the anaerobic bacterium Bacteroides thetaiotaomicron is involved in the degradation of host-derived N-glycans.
History
EC 2.4.1.320 created 2014
Orthology
K18785  beta-1,4-mannooligosaccharide/beta-1,4-mannosyl-N-acetylglucosamine phosphorylase
Genes
VFUvfu_B00533
VFLAL536_06115
ATEPAtep_01920
BCOBcell_1370
AXLAXY_22380
SLMSMM221_05525
GYMGYMC10_2731 GYMC10_3409
PPYPPE_04648
PPMPPSC2_24185
PPOPPM_4802(M1_5246)
PPOLX809_40720
PPQPPSQR21_049000
PPOYRE92_13090
PMSKNP414_01556
PMQPM3016_1863
PMWB2K_09465
PTAHPL003_05755
PBDPBOR_09470 PBOR_09515 PBOR_10055 PBOR_25915 PBOR_26270 PBOR_28855
PGMPGRAT_09165 PGRAT_09475 PGRAT_15390
PODPODO_08065 PODO_19685
PAENP40081_08370 P40081_09305 P40081_09775 P40081_22175 P40081_26050 P40081_26375
PAEFR50345_08115 R50345_09045
PAEQR50912_08610 R50912_08655 R50912_24000
PSTEPSTEL_08745
PAEAR70723_08705 R70723_16935 R70723_23835
PAEER70331_16230 R70331_22830
PAEHH70357_09105 H70357_09470 H70357_13340
PAEJH70737_07880 H70737_08525
PIHUB51_03365
PRIPRIO_1913 PRIO_1921 PRIO_2014 PRIO_3353
PSONJI735_17880 JI735_17925 JI735_18280 JI735_24240
PPEOABE82_24385
PXLBS614_01550
PDHB9T62_03560
PCXLPB68_19560
PKBB4V02_01090
PAIHASL14_13535
PLWD5F53_13285
PLENEIM92_02550 EIM92_12150
PLUTEI981_02585
PTRIKDC22_07110 KDC22_08135 KDC22_08175 KDC22_17260 KDC22_22670
PTJJRJ22_07490
COHNKCTCHS21_13650
CCBClocel_3196
CLBClo1100_3757
CSRCspa_c52780
CPASClopa_3784
CBUTATN24_15320
CEUA7L45_06550
CRWCROST_005210
CFBCLFE_043340
CAUNCLAUR_024870
CNNCNEO_0966
FSAC5Q98_00300 C5Q98_06630
CTHCthe_3112
CTXClo1313_0665
CCLClocl_1327
RUKA4V00_13395
CCECcel_3001
CSSCst_c11350
CSDClst_1087
CTHDCDO33_09820
ESRES1_03380
ESUEUS_01640
CCELCCDG5_2023
EHAEthha_0904
RALRumal_0099
RCHRUM_22240
RUSRBI_I00128
FPAFPR_17240
CAPREQM14_09725 EQM14_11540
CAMLH6X83_02580 H6X83_11010
BHUbhn_I1942
CLEClole_3363 Clole_3404
CEWEKH84_20045 EKH84_20530
RHORHOM_11440
RIXRO1_18100 RO1_39780 RO1_41360
RIMROI_36350
COOCCU_23030
CEVLK421_05065
BYLA4V09_07560
BHANCGC63_15005
CPYCphy_1718 Cphy_2264
ANRAna3638_07150 Ana3638_14295
ACELacsn021_03320 acsn021_26350
ACHTbsdcttw_02620 bsdcttw_17230 bsdcttw_44180
SSUNH9Q77_01920
LBWC3V36_08565
DCADesca_2163
VGUHYG85_12985 HYG85_13620 HYG85_20765
VPYHZI73_02305 HZI73_07080 HZI73_10845 HZI73_15795 HZI73_18550 HZI73_18995
AMICAmi3637_08830
TTETTE2626
TKITKV_c23460
CSCCsac_0296 Csac_0853
ATEAthe_0679 Athe_2555
COBCOB47_0628 COB47_2180
CHDCalhy_0280 Calhy_1988
COWCalow_0544
CKICalkr_1514 Calkr_2192
CLCCalla_0268 Calla_0900
CKNCalkro_0296 Calkro_1950
CCHAELD05_01495 ELD05_10660
CDIACaldiYA01_02580 CaldiYA01_17730
TTMTthe_0138
TSHTsac_0695
TNRThena_0257
TACITDSAC_0250
MASMahau_1676
HPKHprae_2065
HALSD7D81_09475
IFNGM661_06590
LPILLIP_3490
AHKNCTC10172_01380
SNASnas_3437 Snas_3439
HAUHaur_0891
LEKhrd7_07280
PBFCFX0092_B0391
THUGKNN16_09475
PMETG4Y79_19385
OTEOter_2313
OBGVerru16b_00602
OBTOPIT5_07215 OPIT5_11815 OPIT5_23100
RUFIK0V07_00835 K0V07_07235
SOAG3M56_001300
PSLPsta_1702
LPAVPLANPX_1775
PNDPla175_22260
AMOBHG15A2_24750
MCADPan265_03500 Pan265_13470 Pan265_14000
PBASSMSP2_00185 SMSP2_00196 SMSP2_02122
ALUSSTSP2_00410 STSP2_01263
VBLL21SP4_00426
VBCC5Q97_01515 C5Q97_02585 C5Q97_02725
TBETrebr_1917
TPHGFUT81_09735
STASTHERM_c00870
STQSpith_0074
ABACLuPra_05155
BTHBT_1033
BTHOBtheta7330_02647
BFRBF1332
BFSBF9343_1252
BFGBF638R_1332
BFBVU15_05745
BHLBache_1484
BOABovatus_00584
BCELBcellWH2_04281
BCACCGC64_14095
BCAEA4V03_08150
BZGC4H11_04160
BHFC3V43_05350
BISDXK01_010720
BUNBun01g_17560
BSTEK6V31_14815
BFEK6V30_17375
BNOK8P02_03840
BHUMJXR92_008095
BVUBVU_0612
BSABacsa_0833
BDOEL88_22465
BDHGV66_03275
PCOPI6J50_13605
PSOECE91St14_00900
PDIBDI_0634
PARCCI960_07120
PGOLK6V26_11690
PARYA4V02_08585
BVSBARVI_04290
COPRCop2CBH44_31010
PMZHMPREF0659_A6441
PDNHMPREF9137_2294
PDTPrede_1056
PROHMPREF0669_00679
PFUSADJ77_10335
PEOAS203_11020
PJECRM71_15525
POCNCTC13071_00182
PMUFJ4864_10525
PHISJ5A62_05805
PVFJ5A55_05720
PSCJJ4856_00430
ALQC7Y71_007810
AFDAlfi_2317
ASHAL1_19480
AOKA3BBH6_04040 A3BBH6_16990
ACOUA5CBH24_20410
ADAA5CPEGH6_17600
DORIFH5T_07110
DRCG0Q07_00505
MBASALGA_1579 ALGA_4407
RMRRmar_2614
RMGRhom172_2628
FLMMY04_4859
FLLEI427_16975
FYAKMW28_26355
FKAKM029_26190
FJOFjoh_2034
FJGBB050_03365
FCMBIW12_12900
FCRHYN56_20150
FNKE1750_03220
FFLHYN86_16685
FENJ0383_05405
COCCoch_0687
CCMCcan_22860
COLAM608_07510
CHGAXF12_10340
CAPNCBG49_03015
CLKCGC53_06065
CSPUCGC55_06740
CCYNCGC48_04880
CAPHCGC49_09355
CSTOCGC58_07420
CAPQCGC52_09345
CAPFFOC45_00075
ZPRZPR_4182
FBCFB2170_01422
MAREEJ994_10965
POACW731_00330
PHALH9I45_14180
PBATJL193_13025
PCEAJ3359_15550
AHZAPS56_03075
SALTAO058_10025
SEONBWZ22_09920
AALGAREALGSMS7_02958
FEKC1H87_15720
MARFCJ739_2385
AQDD1816_07205
OCIFEZ18_00875
LPALLDL79_10020
SINHLS482_05805
FLGLV716_10840
ZSPMQE36_02400
FBEFF125_13095
FBMMQE35_02030
ORHOrnrh_1984
ORIQ785_09790
EAOBD94_2213
EMNM876_08155
EENBBD30_15830
ELBVO54_00483
EMGBBD33_11870
EGOBBD34_00180
EGMAYC65_07155
ELZFCS00_20115
CHZCHSO_0298
CGNOK18_09015
CIOCEQ15_19240
CHRYCEY12_15615
CPIPCJF12_13220
CARHEGY05_23105
CNKEG343_15340
CJTEG359_15775
CCAUEG346_05040
CBENEG339_06760
CGLENCTC11432_03565
CLACEG342_06565
CRHIKB553_17025
MROMROS_1577 MROS_2100
TMATM1225
TMMTmari_1232
TMITHEMA_08205
TMWTHMA_1251
TMQTHMB_1251
TMXTHMC_1251
TPTTpet_1543
TNPTnap_1567
TRQTRQ2_1593
TNACTN_1346
THQT2812B_07905
THZCELL2_07970
THRTRQ7_08205
TLETlet_1437
PHYAJ81_05250 AJ81_07270
TMETmel_1013
TAFTHA_1292 THA_774
TFEJYK00_08165
FPEFerpe_1840
FIANA23_08980
OCYOSSY52_16370
MARNLN42_06120
MPGTheba_1637 Theba_1714
MINFMESINF_0095
DDFDEFDS_1902
CABYCabys_2432
DTHDICTH_1691
DTUDtur_1800
MBAKMSBR3_1143
MMAMM_2771 MM_2944
MMAZMmTuc01_2818 MmTuc01_3026
MMJMSMAS_1765 MSMAS_1955
MMACMSMAC_1169 MSMAC_1355
MVCMSVAZ_1494 MSVAZ_1827
MEKMSKOL_1437 MSKOL_1804
MSJMSSAC_2416
MSZMSSIH_1994
MSWMSSIT_2042
MHORMSHOH_2244 MSHOH_2526 MSHOH_3014
MPYMpsy_3024
 » show all
Reference
1  [PMID:23943617]
  Authors
Nihira T, Suzuki E, Kitaoka M, Nishimoto M, Ohtsubo K, Nakai H
  Title
Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans.
  Journal
J Biol Chem 288:27366-74 (2013)
DOI:10.1074/jbc.M113.469080
  Sequence
[bth:BT_1033]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.320
IUBMB Enzyme Nomenclature: 2.4.1.320
ExPASy - ENZYME nomenclature database: 2.4.1.320
BRENDA, the Enzyme Database: 2.4.1.320

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