KEGG   ENZYME: 2.4.1.323
Entry
EC 2.4.1.323                Enzyme                                 

Name
7-deoxyloganetic acid glucosyltransferase;
UGT8
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-alpha-D-glucose:7-deoxyloganetate O-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + 7-deoxyloganetate = UDP + 7-deoxyloganate [RN:R10834]
Reaction(KEGG)
R10834
Substrate
UDP-alpha-D-glucose [CPD:C00029];
7-deoxyloganetate [CPD:C20789]
Product
UDP [CPD:C00015];
7-deoxyloganate [CPD:C11636]
Comment
Isolated from the plant Catharanthus roseus (Madagascar periwinkle). Involved in loganin and secologanin biosynthesis. Does not react with 7-deoxyloganetin. cf. EC 2.4.1.324 7-deoxyloganetin glucosyltransferase.
History
EC 2.4.1.323 created 2014
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K21373  7-deoxyloganetic acid glucosyltransferase
Reference
1  [PMID:24104568]
  Authors
Asada K, Salim V, Masada-Atsumi S, Edmunds E, Nagatoshi M, Terasaka K, Mizukami H, De Luca V
  Title
A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle.
  Journal
Plant Cell 25:4123-34 (2013)
DOI:10.1105/tpc.113.115154
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.323
IUBMB Enzyme Nomenclature: 2.4.1.323
ExPASy - ENZYME nomenclature database: 2.4.1.323
BRENDA, the Enzyme Database: 2.4.1.323

DBGET integrated database retrieval system