KEGG   ENZYME: 2.4.1.324Help
Entry
EC 2.4.1.324                Enzyme                                 

Name
7-deoxyloganetin glucosyltransferase;
UDPglucose:iridoid glucosyltransferase;
UGT6;
UGT85A24
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:7-deoxyloganetin O-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + 7-deoxyloganetin = UDP + 7-deoxyloganin [RN:R10835]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:C00029];
7-deoxyloganetin [CPD:C20790]
Product
UDP [CPD:C00015];
7-deoxyloganin [CPD:C06071]
Comment
Isolated from the plants Catharanthus roseus (Madagascar periwinkle) and Gardenia jasminoides (cape jasmine). With Gardenia it also acts on genipin. Involved in loganin and secologanin biosynthesis. Does not react with 7-deoxyloganetate. cf. EC 2.4.1.323 7-deoxyloganetic acid glucosyltransferase.
History
EC 2.4.1.324 created 2014
Pathway
ec00902  Monoterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K21374  7-deoxyloganetin glucosyltransferase
Reference
1  [PMID:21799001]
  Authors
Nagatoshi M, Terasaka K, Nagatsu A, Mizukami H
  Title
Iridoid-specific glucosyltransferase from Gardenia jasminoides.
  Journal
J Biol Chem 286:32866-74 (2011)
DOI:10.1074/jbc.M111.242586
  Sequence
Reference
2  [PMID:24104568]
  Authors
Asada K, Salim V, Masada-Atsumi S, Edmunds E, Nagatoshi M, Terasaka K, Mizukami H, De Luca V
  Title
A 7-deoxyloganetic acid glucosyltransferase contributes a key step in secologanin biosynthesis in Madagascar periwinkle.
  Journal
Plant Cell 25:4123-34 (2013)
DOI:10.1105/tpc.113.115154
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.324
IUBMB Enzyme Nomenclature: 2.4.1.324
ExPASy - ENZYME nomenclature database: 2.4.1.324
BRENDA, the Enzyme Database: 2.4.1.324

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