Entry
Name
1,2-diacylglycerol 3-alpha-glucosyltransferase;
mgs (gene name);
UDP-glucose:diacylglycerol glucosyltransferase;
UDP-glucose:1,2-diacylglycerol glucosyltransferase;
uridine diphosphoglucose-diacylglycerol glucosyltransferase;
UDP-glucose-diacylglycerol glucosyltransferase;
UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase;
UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase;
1,2-diacylglycerol 3-glucosyltransferase (ambiguous)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:1,2-diacyl-sn-glycerol 3-alpha-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + a 1,2-diacyl-sn-glycerol = UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol [RN:
R10850 R12902 ]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:
C00029 ];
1,2-diacyl-sn-glycerol [CPD:
C00641 ]
Product
UDP [CPD:
C00015 ];
1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol [CPD:
C06364 ]
Comment
The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC
2.4.1.336 , monoglucosyldiacylglycerol synthase.
History
EC 2.4.1.337 created 2015
Pathway
Orthology
K19002 1,2-diacylglycerol 3-alpha-glucosyltransferase
Genes
LCJ : NCTC11976_00592(mgtA_1)
MPIN : LGT42_002320 LGT42_003665
NWR : E3U44_09950 E3U44_10035
HAK : KO116_01620 KO116_03650
HSR : HSBAA_09480 HSBAA_44290
HMD : CTT34_12870 CTT34_13415
HTT : HZS52_00715 HZS52_12990
HPIZ : GYM47_12155 GYM47_12720
HPRO : LMS44_03150 LMS44_15130
BSM : BSM4216_3294 BSM4216_3566
LGZ : NCTC10812_02558(pimB_3)
SVB : NCTC12167_00600(ugtP)
SMEN : SAMEA4412692_0129(mgtA)
SFER : NCTC12278_01377(mgtA)
SCAI : NCTC12191_00029(mgtA)
SPSU : NCTC13786_01835(pimB_1)
SPOC : NCTC10925_01327(mgtA)
SAUP : NCTC3168_01326(mgtA_3)
SURN : NCTC13766_01601(mgtA)
SVF : NCTC3166_01422(mgtA_1)
LAI : LAC30SC_02290 LAC30SC_05115
LAY : LAB52_02175 LAB52_05070
LAMY : B1745_05795 B1745_07745
LUU : H4B44_02850 H4B44_10920
LAGL : BEN83_07155 BEN83_10055
ECEC : NCTC12421_01432(pimB_2)
AUI : APT62_02240 APT62_06805
AVS : AWM76_03390 AWM76_08155
CML : BN424_2419(rfaG) BN424_2460(rfaG-2)
CAE : SMB_G2571(mgtA) SMB_G3635
CMAH : C1I91_09965 C1I91_15085
CRW : CROST_032050 CROST_045080
CFB : CLFE_003020 CLFE_031970
CAUN : CLAUR_029980 CLAUR_044230
HHW : NCTC503_01926(mgtA_2)
CSS : Cst_c07770 Cst_c17340
BPRO : PMF13cell1_02046 PMF13cell1_04337 PMF13cell1_04561
LBW : C3V36_09360 C3V36_10780
CLE : Clole_0152 Clole_2186
CEW : EKH84_03935 EKH84_13115
DGI : Desgi_1986 Desgi_4030
PIV : NCTC13079_00132(mgtA)
MBP : MBSPM3_v1c0110(mgs) MBSPM3_v1c0120(mgs)
AHK : NCTC10172_00220(mgtA_1) NCTC10172_00268(mgtA_2)
NAD : NCTC11293_03530(pimA_1)
MFOL : DXT68_08870 DXT68_15565
AAGI : NCTC2676_1_00907(mgtA_2)
NAE : BHE16_04380 BHE16_04390
ORN : DV701_07875 DV701_15600
DCO : SAMEA4475696_0403(cotSA)
PPC : HMPREF9154_0269 HMPREF9154_1531
TES : BW730_00425 BW730_05100
TEZ : BKM78_00290 BKM78_09055
TDF : H9L22_05890 H9L22_15370 H9L22_16430
TLA : TLA_TLA_00060 TLA_TLA_01828(mgs)
PRV : G7070_06030 G7070_10065
NGV : CDO52_05980 CDO52_21295
STRR : EKD16_02860(mgs) EKD16_06985(pimB4)
PRY : Prubr_28730 Prubr_33830
ASLA : NCTC11923_01626(pimB_3)
AVC : NCTC10951_00474(mgtA)
CYC : PCC7424_5786 PCC7424_5790
DMR : Deima_0594 Deima_2949
DGO : DGo_CA2214 DGo_CA2495
DSW : QR90_00770 QR90_08125
DEIN : DAAJ005_08760 DAAJ005_16600
DGA : DEGR_04410 DEGR_09070
CCZ : CCALI_02181 CCALI_02532
TBE : Trebr_0432 Trebr_0970
SFC : Spiaf_0092 Spiaf_0093
SGP : SpiGrapes_0163 SpiGrapes_0367 SpiGrapes_0753 SpiGrapes_1078 SpiGrapes_2889
CTAK : 4412677_01088(pimB_1)
CABY : Cabys_1107 Cabys_2433
DTH : DICTH_0026 DICTH_0815 DICTH_1512
DTU : Dtur_0297 Dtur_0959 Dtur_1622
BBGW : UT28_C0001G0809(mgtA)
MBY : MSBRM_2717 MSBRM_3277
MBAR : MSBR2_2671 MSBR2_3232
MEF : MSWH1_0824 MSWH1_2609
MEQ : MSWHS_0882 MSWHS_1952 MSWHS_2429
MHOR : MSHOH_0171 MSHOH_0781
NAY : HYG81_02015 HYG81_02580 HYG81_04175
HJT : DVR14_18940 DVR14_23070
CSY : CENSYa_0995 CENSYa_0996 CENSYa_1001
PSYT : DSAG12_00646(treT_1)
» show all
Taxonomy
Reference
Authors
Karlsson OP, Dahlqvist A, Vikstrom S, Wieslander A.
Title
Lipid dependence and basic kinetics of the purified 1,2-diacylglycerol 3-glucosyltransferase from membranes of Acholeplasma laidlawii.
Journal
Reference
Authors
Li L, Storm P, Karlsson OP, Berg S, Wieslander A
Title
Irreversible binding and activity control of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii at an anionic lipid bilayer surface.
Journal
Reference
Authors
Berg S, Edman M, Li L, Wikstrom M, Wieslander A.
Title
Sequence properties of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii membranes. Recognition of a large group of lipid glycosyltransferases in eubacteria and archaea.
Journal
Sequence
Reference
Authors
Semeniuk A, Sohlenkamp C, Duda K, Holzl G
Title
A bifunctional glycosyltransferase from Agrobacterium tumefaciens synthesizes monoglucosyl and glucuronosyl diacylglycerol under phosphate deprivation.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.4.1.337