KEGG   ENZYME: 2.4.1.342Help
Entry
EC 2.4.1.342                Enzyme                                 

Name
alpha-maltose-1-phosphate synthase;
glgM (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
ADP-alpha-D-glucose:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (configuration-retaining)
Reaction(IUBMB)
ADP-alpha-D-glucose + alpha-D-glucose-1-phosphate = ADP + alpha-maltose-1-phosphate [RN:R11530]
Reaction(KEGG)
Substrate
ADP-alpha-D-glucose [CPD:C00498];
alpha-D-glucose-1-phosphate
Product
ADP [CPD:C00008];
alpha-maltose-1-phosphate
Comment
The enzyme, found in Mycobacteria, can also use UDP-alpha-D-glucose with much lower catalytic efficiency.
History
EC 2.4.1.342 created 2016
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
Orthology
K16148  alpha-maltose-1-phosphate synthase
Genes
DTX: ATSB10_36280
MAM: Mesau_02696
MTU: Rv1212c(glgA)
MTV: RVBD_1212c
MTC: MT1250(glgA)
MRA: MRA_1221
MTF: TBFG_11236
MTB: TBMG_02770
MTK: TBSG_02784
MTZ: TBXG_002750
MTUR: CFBS_1291
MTD: UDA_1212c
MTUC: J113_08495
MTUE: J114_06535
MTUH: I917_08635
MTUL: TBHG_01195
MTUT: HKBT1_1289
MTUU: HKBT2_1295
MBO: BQ2027_MB1244C(glga)
MBB: BCG_1272c
MBT: JTY_1247
MBX: BCGT_1043
MAF: MAF_12310
MMIC: RN08_1355
MPA: MAP_2565
MAO: MAP4_1255
MAVI: RC58_06210
MAVU: RE97_06205
MAV: MAV_1357
MAVD: NF84_06050
MAVR: LA63_06175
MAVA: LA64_06190
MIT: OCO_12660
MIA: OCU_12620
MID: MIP_02010
MYO: OEM_12800
MIR: OCQ_12640
MMC: Mmcs_4001
MKM: Mkms_4075
MJL: Mjls_4231
MMI: MMAR_4226
MMM: W7S_06165
MHAD: B586_07675
MSG: MSMEI_4954(glgA)
MVA: Mvan_4504
MGI: Mflv_2191
MPHL: MPHLCCUG_04044(glgA)
MVQ: MYVA_4281
MAB: MAB_1351c
MABB: MASS_1351
MABO: NF82_06805
MCHE: BB28_06670
MSTE: MSTE_01317
ASD: AS9A_1341
CGL: NCgl1072(Cgl1117)
CGB: cg1268(glgA)
CGU: WA5_1072(GlgA)
CGT: cgR_1201
CGM: cgp_1268(glgA)
CGJ: AR0_06085
CEF: CE1174
CDI: DIP0991
CDP: CD241_0899(glgA)
CDH: CDB402_0867(glgA)
CDT: CDHC01_0899(glgA)
CDE: CDHC02_0898(glgA)
CDR: CDHC03_0895(glgA)
CDA: CDHC04_0905(glgA)
CDZ: CD31A_0997(glgA)
CDB: CDBH8_0960(glgA)
CDS: CDC7B_0904(glgA)
CDD: CDCE8392_0896(glgA)
CDW: CDPW8_0955(glgA)
CDV: CDVA01_0862(glgA)
CDIP: ERS451417_00894(glgA)
CJK: jk1384(glgA)
CAR: cauri_0997(glgA)
CPL: Cp3995_0800(glgA)
CPG: Cp316_0816(glgA)
CPP: CpP54B96_0799(glgA)
CPK: Cp1002_0788(glgA)
CPQ: CpC231_0788(glgA)
CPX: CpI19_0788(glgA)
CPZ: CpPAT10_0786(glgA)
COR: Cp267_0822(glgA)
COP: Cp31_0796(glgA)
COD: Cp106_0772(glgA)
COS: Cp4202_0778(glgA)
COI: CpCIP5297_0804(glgA)
COE: Cp258_0793(glgA)
COU: Cp162_0787(glgA)
CPSE: CPTA_01343
CPSU: CPTB_00189
CPSF: CPTC_01333
CRD: CRES_1459(glgA)
CUN: Cul210932_0875(glgA)
CUS: CulFRC11_0841(glgA)
CUQ: Cul210931_0837(glgA)
CUZ: Cul05146_0897(glgA)
CUJ: CUL131002_0853c(glgA)
COA: DR71_1820(glgA)
CSX: CSING_05490(glgA)
CMQ: B840_04565(glgA)
CKU: UL82_07730(glgA)
CCJ: UL81_04580(glgA)
CMV: CMUST_06080(glgA)
CEI: CEPID_04765(glgA)
CTED: CTEST_04905(glgA)
CUT: CUTER_04130(glgA)
CDX: CDES_05405(glgA)
CSP: WM42_0373(glgA)
CPHO: CPHO_07835
CGV: CGLAU_04940(glgA)
CAQU: CAQU_04785
CAMG: CAMM_08490
NFA: NFA_47250
NFR: ERS450000_05204(glgA_2)
NNO: NONO_c64270(glgA)
NSR: NS506_01933(glgA)
RER: RER_41610(glgA)
REY: O5Y_19445
ROP: ROP_60340(glgA)
REQ: REQ_14430
RHB: NY08_5052
RFA: A3L23_03109(glgA)
RHS: A3Q41_00220(glgA)
RHU: A3Q40_02306(glgA)
GBR: Gbro_3306
GOR: KTR9_3346
TPR: Tpau_1174
SRT: Srot_1592
SCO: SCO0962(glgA)
SMA: SAVERM_7253(glgA)
SGB: WQO_31760
SCB: SCAB_11771(glgA)
SHY: SHJG_7839
SLV: SLIV_33125(glgA)
SGU: SGLAU_29155(glgA)
SAMB: SAM23877_6583(glgA)
SRW: TUE45_00138(glgA)
SLE: sle_07320(sle_07320)
STRD: NI25_03400
SALF: SMD44_07637(glgA)
SFK: KY5_7367
CMI: CMM_1718
CMS: CMS1962
CMC: CMN_01698
MTS: MTES_3626
AMIN: AUMI_16080
ART: Arth_2141
ARM: ART_0692
ARX: ARZXY2_1842(glgA)
AAU: AAur_2137(glgA)
ACH: Achl_1888
KRH: KRH_12730
BCV: Bcav_2317
JDE: Jden_1173
LMOI: VV02_14790
XCE: Xcel_1421
IDO: I598_0854(glgA)
CFL: Cfla_1691
CFI: Celf_1719
SERJ: SGUI_0281
DCO: SAMEA4475696_1745(glgA)
PAC: PPA0639
PAK: HMPREF0675_3706(glgA)
PACC: PAC1_03325
PACH: PAGK_1490
CACN: RN83_03715
CGRN: 4412665_00939(glgA)
PFR: PFREUD_16190(glgA)
PFRE: RM25_1536
PPC: HMPREF9154_1178(glgA)
MPH: MLP_43020(glgA)
NCA: Noca_3718
NDK: I601_0412(glgA)
KFL: Kfla_5498
SRO: Sros_6261
FAL: FRAAL4552
ACE: Acel_1822
NML: Namu_2152
GOB: Gobs_1119
MMAR: MODMU_1180
KRA: Krad_2900
AMD: AMED_4464
AMN: RAM_22735
AMM: AMES_4409
AMZ: B737_4409
PDX: Psed_1025
PSEA: WY02_21295
PSEE: FRP1_22030
PSEH: XF36_20280
AMI: Amir_0793
SESP: BN6_08760(glgA)
KAL: KALB_954
ACTI: UA75_04680
ACAD: UA74_04565
AHG: AHOG_04420(glgA)
ALL: CRK61709
MIL: ML5_2216
ASE: ACPL_5093(glgA)
ACTN: L083_4038(glgA)
AFS: AFR_21025
ACTS: ACWT_4963
AHE: Arch_0927
MCU: HMPREF0573_11587(glgA)
TPYO: X956_05280
BLO: BL0826(glgA)
BLJ: BLD_0562(rfaG1)
BLN: Blon_1477
BLON: BLIJ_1526
BLF: BLIF_0913
BLL: BLJ_0922
BLB: BBMN68_570(rfaG1)
BLM: BLLJ_0790
BLG: BIL_10460
BAD: BAD_0751(glgA)
BADL: BADO_0799
BLA: BLA_1404(glgA)
BBB: BIF_00645
BBC: BLC1_0848
BLV: BalV_0854
BLW: W7Y_0890
BLS: W91_0911
BANI: Bl12_0830
BANL: BLAC_04515
BANM: EN10_04505
BDE: BDP_1081
BDN: BBDE_1035
BBI: BBIF_0875
BBP: BBPR_0846
BBF: BBB_0849(glgA)
BBV: HMPREF9228_0920(glgA)
BBRU: Bbr_0942
BBRE: B12L_0872
BBRV: B689b_0952
BBRJ: B7017_1037
BBRC: B7019_1024
BBRN: B2258_0908
BBRS: BS27_0952
BBRD: BBBR_0903
BKS: BBKW_0875
BANG: BBAG_0786
BCAT: BBCT_0799
BPSC: BBPC_0854
BSCA: BBSC_1242
SIJ: SCIP_0639
PDO: PSDT_0843
TBI: Tbis_2112
 » show all
Taxonomy
Reference
1  [PMID:27513637]
  Authors
Koliwer-Brandl H, Syson K, van de Weerd R, Chandra G, Appelmelk B, Alber M, Ioerger TR, Jacobs WR Jr, Geurtsen J, Bornemann S, Kalscheuer R
  Title
Metabolic Network for the Biosynthesis of Intra- and Extracellular alpha-Glucans  Required for Virulence of Mycobacterium tuberculosis.
  Journal
PLoS Pathog 12:e1005768 (2016)
DOI:10.1371/journal.ppat.1005768
  Sequence
[mtu:Rv1212c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.342
IUBMB Enzyme Nomenclature: 2.4.1.342
ExPASy - ENZYME nomenclature database: 2.4.1.342
BRENDA, the Enzyme Database: 2.4.1.342

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