KEGG ENZYME: 2.4.1.345

ENZYME: 2.4.1.345

Entry

EC 2.4.1.345                Enzyme

Name

phosphatidyl-myo-inositol alpha-mannosyltransferase;
mannosyltransferase PimA;
PimA;
guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase (ambiguous)

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

GDP-alpha-D-mannose:1-phosphatidyl-1D-myo-inositol 2-alpha-D-mannosyltransferase (configuration-retaining)

Reaction(IUBMB)

GDP-alpha-D-mannose + 1-phosphatidyl-1D-myo-inositol = GDP + 2-O-(alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol [RN:R11702 R12038]

Reaction(KEGG)

R11702 R12038(G)

Substrate

GDP-alpha-D-mannose [CPD:C00096];
1-phosphatidyl-1D-myo-inositol [CPD:C01194]

Product

GDP [CPD:C00035];
2-O-(alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol [CPD:C21606]

Comment

Requires Mg2+. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs).

History

EC 2.4.1.345 created 2017

Pathway

ec00571

Lipoarabinomannan (LAM) biosynthesis

ec01100

Metabolic pathways

Orthology

K08256

phosphatidyl-myo-inositol alpha-mannosyltransferase

Genes

CAMA:

F384_03810

CFAR:

CI104_08530

CTEL:

GBC03_21465

PRAG:

EKN56_09580

LEZ:

GLE_2461

ALTO:

AltI4_27610

MEJ:

Q7A_1432

HYB:

Q5W_14045

HHT:	F506_20065

AZA:

AZKH_0597

AZI:	AzCIB_3683

MEX:

Mext_0248

MPO:

Mpop_1268

MET:

M446_4034

MNO:

Mnod_3170

MEE:	DA075_25370

METD:

C0214_05545

METI:

DK427_15040

BID:

Bind_0839

SIW:	GH266_09650

TID:	Thein_1081

TMAI:

FVE67_07225

ADE:	Adeh_2418 Adeh_3504 Adeh_4147

ACP:	A2cp1_1540 A2cp1_3661 A2cp1_4300

AFW:	Anae109_1460 Anae109_4290

ANK:	AnaeK_1445 AnaeK_3592 AnaeK_4278

AORY:

AMOR_06500(pimA_1)

TRO:

trd_1965

STI:

Sthe_0282

TNR:	Thena_0576

TACI:

TDSAC_0544

VBA:	IMCC26134_14880

SSPE:

ACGY09_12000

SUS:

Acid_0304

RCG:	N7E81_10660

PTRI:

KDC22_17590

ERZ:	ER308_19055

EUZ:	DVS28_a1678

MTU:	Rv2610c(pimA)

MTV:	RVBD_2610c

MTC:

MT2685

MRA:	MRA_2638(pimA)

MTF:	TBFG_12629

MTB:	TBMG_01361

MTK:	TBSG_01371

MTZ:	TBXG_001350

MTG:	MRGA327_16080

MTI:	MRGA423_16330

MTE:	CCDC5079_2408

MTUR:

CFBS_2762(pimA)

MTL:	CCDC5180_2379

MTO:	MTCTRI2_2659(pimA)

MTD:	UDA_2610c(pimA)

MTN:	ERDMAN_2870(pimA)

MTJ:	J112_14005

MTUB:

MT7199_2643

MTUE:

J114_13960

MTX:	M943_13490

MTUL:

TBHG_02548

MTUT:

HKBT1_2753(pimA)

MTUU:

HKBT2_2756(pimA)

MTQ:	HKBS1_2760(pimA)

MBO:	BQ2027_MB2642C(pimA)

MBB:	BCG_2635c(pimA)

MBT:	JTY_2629(pimA)

MBM:	BCGMEX_2628c(pimA)

MBK:	K60_027150

MBX:

BCGT_2456

MAF:	MAF_26280(pimA)

MMIC:

RN08_2891

MCE:	MCAN_26531(pimA)

MCQ:	BN44_60073(pimA)

MCV:	BN43_40287(pimA)

MCX:	BN42_40595(pimA)

MCZ:	BN45_51003(pimA)

MORY:

MO_002739(pimA)

MLE:

ML0452

MLB:

MLBr00452

MPA:

MAP_2712c

MAO:

MAP4_1104

MAVI:

RC58_05485

MAVU:

RE97_05480

MAV:

MAV_3486

MAVM:

MAA44156_00973(pimA_1)

MIT:

OCO_33240

MIA:

OCU_33140

MID:

MIP_05001

MYO:

OEM_33370

MCHI:

AN480_17635

MIR:

OCQ_34380

MMAL:

CKJ54_15495

MLP:

MLM_1611

MMAN:

MMAN_05220(pimA)

MSER:

MTY59_50590(pimA)

MSA:	Mycsm_02705

MUL:	MUL_3252(pimA)

MMI:	MMAR_2092(pimA)

MMAE:

MMARE11_20350(pimA)

MLI:	MULP_03061(pimA)

MPSE:

MPSD_21280(pimA)

MSHO:

MSHO_50680(pimA)

MMC:

Mmcs_2246

MKM:

Mkms_2293

MJL:

Mjls_2285

MMM:

W7S_16645

MKN:	MKAN_26055

MYV:	G155_13350

MYE:	AB431_12530

MHAD:

B586_14000

MDX:	BTO20_19335

MSHG:

MSG_01937(pimA)

MFJ:	MFLOJ_13100(pimA)

MSTO:

MSTO_14470(pimA)

MSIM:

MSIM_04150(pimA)

MSAK:

MSAS_00570(pimA)

MKU:	I2456_10335

MLW:	MJO58_10525

MXE:	MYXE_30060(pimA)

MNV:	MNVI_36070(pimA)

MPAG:

C0J29_12025

MNM:	MNVM_36570(pimA)

MGOR:

H0P51_11475

MCOO:

MCOO_03160(pimA)

MBAI:

MB901379_01929(pimA)

MSEO:

MSEO_07600(pimA)

MHEK:

JMUB5695_02979(pimA)

MGAU:

MGALJ_10290(pimA)

MLJ:	MLAC_11190(pimA)

MBRD:

MBRA_44180(pimA)

MSHJ:

MSHI_19720(pimA)

MMAM:

K3U93_09505

MSPG:

F6B93_08585

MOT:	LTS72_13935

MLM:	MLPF_0650(pimA)

MPAA:

MKK62_14785

MMEH:

M5I08_17925

MKY:	IWGMT90018_36860(pimA)

MADI:

A7U43_18235

MWU:	PT015_03060

MYW:	BVC93_29270

MYJ:	BCA37_13545

MHAF:

ACEL92_16955

MSM:	MSMEG_2935

MSG:	MSMEI_2861(pimA)

MSB:	LJ00_14605

MSN:	LI99_14610

MSH:	LI98_14615

MVA:

Mvan_2562

MAUS:

JN090_11870

MGI:

Mflv_3834

MSP:	Mspyr1_31770

MCB:	Mycch_2289

MNE:	D174_12480

MYN:	MyAD_12240

MFT:	XA26_27610

MPHL:

MPHLCCUG_03040(pimA_4)

MVQ:

MYVA_2455

MLL:	B1R94_16795

MRH:	MycrhN_5490

MTHN:

4412656_02663(pimA_1)

MHAS:

MHAS_02272(pimA_1)

MDU:	MDUV_17770(pimA)

MCHT:

MCHIJ_43050(pimA)

MDR:	MDOR_15860(pimA)

MAUU:

NCTC10437_02393(pimA)

MMAG:

MMAD_24800(pimA)

MMOR:

MMOR_39360(pimA)

MFX:	MFAL_05100(pimA)

MAIC:

MAIC_21910(pimA)

MIJ:	MINS_23160(pimA)

MALV:

MALV_11870(pimA)

MTY:	MTOK_42710(pimA)

MPSC:

MPSYJ_41350(pimA)

MARZ:

MARA_15080(pimA)

MGAD:

MGAD_13920(pimA)

MHEV:

MHEL_46500(pimA)

MSAR:

MSAR_34320(pimA)

MANY:

MANY_07950(pimA)

MAUB:

MAUB_01560(pimA)

MPOF:

MPOR_28660(pimA)

MPHU:

MPHO_11510(pimA)

MMUC:

C1S78_012510

MMAT:

MMAGJ_59210(pimA)

MBOK:

MBOE_47170(pimA)

MFG:	K6L26_18795

MSEI:

MSEDJ_36610(pimA)

MFLV:

NCTC10271_03012(pimA)

MCEE:

MCEL_12590(pimA)

MBRM:

L2Z93_002265

MMON:

EWR22_11450

MGO:	AFA91_25190

MHOL:

K3U96_15155

MSEN:

K3U95_10950

MPAE:

K0O64_12300

MRF:	MJO55_11485

MDF:	K0O62_12785

MCRO:

MI149_13090

MGRO:

FZ046_17675

MFRE:

EXE63_31495

MBUG:

MU0053_002870

MYQ:	TUM20985_33210(pimA)

MFLU:

HZU40_17830

MYH:	QU592_13615

MPAT:

MPNTM1_04471(pimA)

MKR:	MKOR_11500(pimA)

MPAK:

MIU77_11265

MAB:

MAB_2894c

MMV:	MYCMA_1602

MABB:

MASS_2835

MABL:

MMASJCM_2852

MCHE:

BB28_14485

MIZ:	BAB75_15640

MSTE:

MSTE_02857

MSAO:

MYCSP_13025

MSAL:

DSM43276_02615(pimA_2)

MJD:	JDM601_2393(pimA)

MTER:

4434518_02322(pimA)

MMIN:

MMIN_01020(pimA)

MHIB:

MHIB_18480(pimA)

MHER:

K3U94_13570

MVM:	MJO54_13355

MKK:	MU0083_002232

ASD:

AS9A_1808

CGL:	Cgl1667(Cgl1667)

CGB:

cg1876

CGU:

WA5_1603

CGT:

cgR_1712

CGS:	C624_09075

CGG:	C629_09085

CGM:

cgp_1876

CGJ:

AR0_08830

CGQ:	CGLAR1_08695

CGX:	SB89_08525

CEF:

CE1781

CDI:

DIP1384

CDP:	CD241_1326(pimA)

CDH:	CDB402_1295(pimA)

CDT:	CDHC01_1326(pimA)

CDE:	CDHC02_1285(pimA)

CDR:	CDHC03_1305(pimA)

CDA:	CDHC04_1306(pimA)

CDZ:	CD31A_1401(pimA)

CDB:	CDBH8_1378(pimA)

CDS:	CDC7B_1388(pimA)

CDD:	CDCE8392_1301(pimA)

CDW:	CDPW8_1374(pimA)

CDV:	CDVA01_1269(pimA)

CDIP:

ERS451417_01400(pimA)

CJK:	jk1062(pimA)

CUR:

cu0929

CUA:	CU7111_0915(pimA)

CAR:	cauri_1428(pimA)

CKP:	ckrop_1036(pimA)

CPU:	CPFRC_05960

CPL:	Cp3995_1209(pimA)

CPG:	CP316_06110

CPP:	CpP54B96_1204(pimA)

CPK:	CP1002_07185

CPQ:	CPC231_05965

CPX:	CPI19_05555

CPZ:	CpPAT10_1180(pimA)

COR:	Cp267_1237(pimA)

COP:	CP31_06340

COD:	Cp106_1164(pimA)

COS:	Cp4202_1174(pimA)

COI:	CPCIP5297_06125

COE:	CP258_06125

COU:	CP162_05170

CPSE:

CPTA_01758

CPSU:

CPTB_02005

CPSF:

CPTC_01749

CRD:	CRES_1144(pimA)

CUL:	CULC22_01294(pimA)

CUC:	CULC809_01280(pimA)

CUE:	CULC0102_1409(pimA)

CUN:	Cul210932_1348

CUQ:	Cul210931_1245

CUZ:	Cul05146_1321

CUJ:	CUL131002_1276c

CUS:	CulFRC11_1261

CVA:	CVAR_1555(pimA)

CHN:	A605_08130

CCN:	H924_07885

CTER:

A606_06170

CMD:	B841_07445

CAZ:	CARG_05435

CFN:	CFAL_05930

CCG:	CCASEI_06730

CVT:	B843_07790

CGY:	CGLY_08115(pimA)

CAX:	CATYP_04635

CII:	CIMIT_07025

CUV:	CUREI_06770

COA:	DR71_2131(pimA)

CDO:	CDOO_08010

CHM:	B842_07455

CSX:	CSING_07790(pimA)

CMQ:	B840_07005(pimA)

CKU:	UL82_05885(pimA)

CCJ:	UL81_06675(pimA)

CMV:	CMUST_08795(pimA)

CEI:	CEPID_07140(pimA)

CTED:

CTEST_07480(pimA)

CUT:	CUTER_06230(pimA)

CLW:	CLAC_05850

CDX:	CDES_08330(pimA)

CSP:	WM42_2557(pimA)

CSTA:

CSTAT_06040

CCJZ:

ccrud_08060

CFK:	CFRA_05085

CPHO:

CPHO_05410

CFC:	CFLV_07000

CGV:	CGLAU_07065(pimA)

CSTR:

CBE89_06450

CSPH:

CSPHI_06050

CAMG:

CAMM_06235

CMIN:

NCTC10288_01082(pimA)

CPEG:

CPELA_04930(pimA)

CXE:	FOB82_11695

CEE:	CENDO_06400(pimA)

CSAN:

E3227_08710

CGK:	CGERO_06240(pimA)

CRF:	FRC0190_01415

CRL:	NCTC7448_02033(pimA)

CCHO:

CCHOA_06555(pimA)

CPRE:

Csp1_13010(pimA)

CPSO:

CPPEL_05135(pimA)

CSUR:

N24_1753(pimA)

CCYS:

SAMEA4530656_0969(pimA)

CMAT:

HBA49_01000

CYZ:	C3B44_04980

CKF:	I6I12_06065

CANS:

GP473_04845

CLIA:

C3E79_06235

CPRP:

I6I69_00515

CAMC:

I6I65_02070

CGLU:

I6J20_02965

CUO:	CUROG_05405(pimA)

CLIZ:

G7Y31_06515

CSIL:

CBE74_06960

CTUB:

I6I74_00150

CLUJ:

IAU68_06555

CQN:	G7Y29_06080

CKW:	CKALI_06415(pimA)

CCOE:

CETAM_07460(pimA)

COK:	COCCU_08125(pimA)

CZO:	IAU67_04835

CORY:

FQV43_05700

CMF:	GWO64_005435

CWK:	IA203_07170

CUW:	LH390_06430

CPOY:

GP475_06550

CACC:

CACC_07060(pimA)

CFY:	I6L56_02150

CPSL:

KBP54_06420

CHIN:

J5O04_07485

CJH:	CJEDD_07185(pimA)

CPSP:

L9H27_05910

CMAS:

CMASS_05935(pimA1)

CHEI:

CHEID_05480(pimA)

CIHU:

CIHUM_06360(pimA)

CCOY:

CCOY_07090(pimA)

CHAD:

CHAD_06870(pimA)

CFG:	CFREI_07745(pimA)

CAQM:

CAQUA_05120(pimA)

CCAW:

CCANI_08060(pimA)

CAUI:

CAURIS_06415(pimA)

CFAC:

CFAEC_07955(pimA)

CFOU:

CFOUR_06425(pimA1)

CFEU:

CFELI_07740(pimA1)

CAUS:

CAURIC_05815(pimA)

CATR:

CATRI_07275(pimA)

CDUR:

CDUR_07390(pimA)

CCOU:

CCONF_06695(pimA)

CHAN:

CHAN_06375(pimA)

CAFE:

CAFEL_06295(pimA)

CGF:	CGUA_07325(pimA)

CGOI:

CGOTT_06575(pimA)

CAPP:

CAPP_06720(pimA)

CBOV:

CBOVI_05115(pimA)

CBRE:

QP027_06165

CPYR:

CYJ47_05365

CRIE:

AK829_02770

CIK:	H0194_00940

CORN:

BJP05_04535

CGP:	KBP53_06685

CPSK:

Q0N40_05500

CHES:

R3O64_07420

CBEL:

ABMV07_07775

CORS:

PAB09_07710

CORE:

RIU96_08985

CRHN:

QP973_007205

CMAL:

ACMX9P_05165

BFV:	C628_09050

NFA:

NFA_37080

NFR:	ERS450000_00344(pimA_1)

NCY:	NOCYR_3606(pimA)

NBR:	O3I_028930

NNO:	NONO_c46230

NSL:	BOX37_19780

NSR:	NS506_03888(pimA)

NTP:	CRH09_23165

NOZ:	DMB37_07920

NOD:	FOH10_18025

NAH:	F5544_28520

NAD:	NCTC11293_03465 NCTC11293_05069(pimA_3)

NWL:	NWFMUON74_29090(pimA)

NIE:	KV110_28110

NTC:	KHQ06_29285

NHU:	H0264_28365

NYA:	LTV02_05705

NGP:	LTT66_25005

NSPU:

IFM12276_18630(pimA)

NYU:	D7D52_25930

NVU:	V7968_36760

RHA:	RHA1_ro06882

RER:	RER_29070(pimA)

REY:

O5Y_13250

REB:	XU06_13470

RQI:	C1M55_14480

ROP:	ROP_68610(pimA)

ROA:	Pd630_LPD03508

RPY:	Y013_02060

RBY:	CEJ39_12755

RAV:	AAT18_12460

RHW:	BFN03_06725

RRZ:	CS378_02210

RHU:	A3Q40_01566(pimA_1)

RHQ:	IM25_16045

RHOD:

AOT96_24690

RRT:	4535765_02115(pimA_1)

RCR:	NCTC10994_00750(pimA_1)

RTM:	G4H71_20605

RKO:	JWS14_37085

RGO:	KYT97_02120

ROZ:	CBI38_16910

RPSK:

JWS13_07110

RGOR:

NMQ04_09370

RHOP:

D8W71_16240

RHOO:

RA302_13710

RHOU:

KZJ41_13580

RHOW:

A4U64_12260

RHOJ:

JVH1_01565

RHOS:

QWW67_02200

RHOQ:

QWW98_02205

RHOY:

QNA09_10015

RHOH:

CPI83_15540

RHOX:

RBB84_06195

RHJS:

OYT95_02395

RSF:	OED52_09305

RHZQ:

GO592_15405

RHZG:

BO226_06585

RHBH:

A0W34_13800

RHPD:

U9J23_10550

RHON:

EHW12_14090

RHWB:

FND50_16645

RHSQ:

E7742_06225

RHWY:

GFS60_05977(pimA)

RHDM:

HFP48_13010

RHWQ:

HUN07_11945

RHMM:

ISO16_02200

RHZP:

HYG77_30125

RHRC:

P0M12_26235

RHNY:

ACBG85_13595

RHRD:

RDE2_21170

RHDK:

PST05_35000

RHMZ:

QWU03_02835

RFA:	A3L23_04421(pimA_4)

RHS:	A3Q41_03846(pimA_2)

REQ:

REQ_20790

PDEF:

P9209_20800

PSOW:

ABI214_03350

WHR:	OG579_01605

GBR:

Gbro_2291

GPO:	GPOL_c21950(pimA)

GOR:

KTR9_2208

GOQ:	ACH46_09620

GTA:	BCM27_11805

GOC:	CXX93_13280

GIT:	C6V83_10000

GRU:	GCWB2_13855(pimA)

GOM:	D7316_00816(pimA_1)

GAV:	C5O27_14245

GOD:	GKZ92_12615

GOJ:	GR168_10845

GAM:	GII34_10775

GPD:	GII33_10405

GJI:	H1R19_11060

GOI:	LK459_22435

GHN:	MVF96_11205

GAMI:

IHQ52_16385

GMG:	NWF22_21600

GSI:	P5P27_08650

GOO:	HUN08_08635

GOP:	ACE11G_09530

SPIN:

KV203_08915

TPR:

Tpau_1923

TSM:	ASU32_10410

TPUL:

TPB0596_26710(pimA)

TSD:	MTP03_21190

SRT:

Srot_1804

DTM:	BJL86_1760

DIT:	C3V38_14395

DIZ:	CT688_08580

DPC:	A6048_08850

DLU:	A6035_08400

DKN:	NHB83_08145

DCD:	VYL96_08465

DID:	GJR88_02738

CBQ:	AL705_00580

TOY:	FO059_09810

SCO:	SCO1525(SCL2.15c)

SALB:

XNR_5328

SMA:	SAVERM_6828

SGR:

SGR_6010

SGB:

WQO_05350

SFI:

SFUL_1036

SANL:

KZO11_04965

SGRF:

SGFS_092710

SCYE:

R2B67_31080

SCB:	SCAB_74821

SSX:	SACTE_0928

SVL:	Strvi_3023

SHY:

SHJG_2949

SHO:	SHJGH_2713

SRC:	M271_10410

SMAL:

SMALA_6493

SAUO:

BV401_36385

SSOI:

I1A49_36265

SANT:

QR300_08750

SFA:

Sfla_5339

SBH:

SBI_02403

SVE:

SVEN_1125

SDV:	BN159_7064(pimA)

SALS:

SLNWT_6409

STRP:

F750_1283

SCI:	B446_07865

SLV:	SLIV_30150(pimA)

SGU:	SGLAU_06155(pimA)

SVT:	SVTN_06990

STRE:

GZL_07170

SCW:	TU94_06295

SLD:

T261_6732

SLC:	SL103_11910

SXI:	SXIM_03800

STRM:

M444_07965

STRC:

AA958_03325

SAMB:

SAM23877_1576(pimA)

SPRI:

SPRI_6038

SCZ:	ABE83_30470

SCX:	AS200_36050

SRW:	TUE45_01932(pimA)

STRF:

ASR50_07200

SLE:	sle_55860(sle_55860)

SRN:	A4G23_00770(pimA)

SPAV:

Spa2297_05785

STRT:

A8713_05245

SCLF:

BB341_24180

SGS:	AVL59_34115

STSI:

A4E84_07485

SKY:	D0C37_28685

SALW:

CP975_05725

SGM:	GCM10017557_68010

SCAD:

DN051_31090

SPHW:

NFX46_28075

SGRS:

V9K83_27055

SLS:	SLINC_1710

SNR:	SNOUR_32830(pimA)

SALU:

DC74_1981

SALL:

SAZ_10490

SPLU:

LK06_004325

STRD:

NI25_31590

SNW:	BBN63_29115

SSIA:

A7J05_29465

SVU:	B1H20_04550

SPUN:

BFF78_33955

SGV:	B1H19_09585

SLAU:

SLA_1022

SALF:

SMD44_01565(pimA)

SALJ:

SMD11_5509(pimA)

SLX:	SLAV_29875(pimA)

STRO:

STRMOE7_08175

SFK:

KY5_1309c

SNZ:	DC008_05625

SGE:	DWG14_06971(pimA)

SRJ:

SRO_5952

SVQ:	N6Q81_07010

SLK:	SLUN_06910

SDX:	C4B68_33285

SGD:	ELQ87_32170

SQZ:	FQU76_04385

SCYA:

EJ357_08400

SAST:

CD934_28145

SNQ:	CP978_07145

STIR:

DDW44_11610

SKA:	CP970_36225

SGZ:	C0216_21015

SVN:	CP980_27140

SNK:	CP967_28840

SHAW:

CEB94_07935

SRK:	FGW37_06130

SFIC:

EIZ62_27605

SGAL:

CP966_05970

SSPO:

DDQ41_01125

SVR:	CP971_27085

SPAD:

DVK44_03455

SFY:	GFH48_32905

SAQU:

EJC51_10190

SGF:	HEP81_06262

SCAV:

CVT27_04175

SSEO:

D0Z67_04505

SBY:	H7H31_04160

SRIM:

CP984_34040

SSUB:

CP968_26960

SPHV:

F9278_07090

SCIN:

CP977_06595

SFUG:

CNQ36_06140

SPAC:

B1H29_29995

STSU:

B7R87_04355

SCHA:

CP983_35570

SGX:	H4W23_07500

SCOE:

CP976_08570

SBAT:

G4Z16_29295

SSPB:

CP982_08940

SNF:	JYK04_02184(pimA)

SPLA:

CP981_07270

SBRO:

GQF42_10205

STUI:

GCM10017668_10930

SATA:

C5746_08065

SCHF:

IPT68_06650

SHUN:

DWB77_06227(pimA_2)

SHAR:

HUT13_02590

SCYG:

S1361_08370(pimA)

SFEU:

IM697_15050

SLIA:

HA039_28640

SDW:	K7C20_06375

SVD:	CP969_08560

SCAL:

I6J39_04730

SAUH:

SU9_005330

SFB:	CP974_04030

SMOB:

J7W19_05125

SPRA:

CP972_06600

SPEU:

CGZ69_06095

SROI:

IAG44_32990

SXN:	IAG42_29510

SGJ:	IAG43_04945

SHK:	J2N69_05655

SANU:

K7396_29455

SACT:

DMT42_06540

SMAO:

CAG99_25370

SGOB:

test1122_00790

SINE:

KI385_09685

SLF:	JEQ17_38120

SDEC:

L3078_08635

SAOV:

G3H79_31125

SDUR:

M4V62_34475

SYAN:

NRK68_06745

SRUG:

F0345_03640

SAKB:

K1J60_36805

STAA:

LDH80_31940

SNIG:

HEK616_20360

SVIO:

HWN34_26905

SCAE:

IHE65_36915

STUB:

MMF93_05280

SSPN:

LXH13_07540

SCIR:

STRCI_001575

SXT:	KPP03845_101762(pimA)

SLON:

LGI35_10755

SDRZ:

NEH16_26510

STUD:

STRTU_005915

STEE:

F3L20_10250

SENG:

OJ254_20870

SGK:	PET44_06555

SYUN:

MOV08_33190

SARG:

HKX69_28640

SJN:	RI060_34905

SCYN:

N8I84_08300

SOV:	QZH56_29880

SFIY:

F0344_30955

SHAU:

K9S39_35580

SKG:	KJK29_31765

SCOA:

QU709_36090

SLAI:

P8A22_32430

SROC:

RGF97_28445

SFP:	QUY26_33475

SCHG:

NRO40_04435

STTN:

BSL84_06445

SINN:

ABB07_31160

STRZ:

OYE22_04005

SCAY:

PYS65_29815

KBU:	Q4V64_09335

SARM:

DVA86_06590

SPRF:

K4G22_01615

SLUO:

PS467_33720

STPB:

QR97_33065

SMIB:

SMIR_32320

SCAJ:

O1G22_34170

STRW:

QHG49_28595

STRL:

HEP84_12590

STSD:

HEP87_12705

SRPZ:

HEP85_08345

SCHE:

QRN89_05665

SGLY:

P8A20_31100

SCAT:

P8A18_04490

STII:

DRB96_03910

STIC:

DRB89_08375

SABD:

N8I86_08420

STRV:

EZV63_05835

SPAZ:

ABXI76_31325

SPIH:

ABXR15_25430

SMOD:

POD33_27980

SPOF:

P8A21_06590

STBR:

ABDE16_30170

SGRO:

UBV09_05825

STAC:

ABII15_06830

STVB:

OH133_32645

SSOC:

ABZO31_05110

SSLI:

R2D22_30505

STYI:

C9F11_07965(pimA)

SCIT:

V2W30_06790

SSIR:

WAB15_08475

STRJ:

H7827_26865

SEXP:

SLV14_006485

SFLU:

ACKTSN_37900

SOKE:

ACE1N8_06060

SSTO:

ACE1OC_32730

SLUA:

AB8735_08310

STGO:

KBP30_32700

STCM:

SCMC78_63830

STID:

G7Z12_30730

STCZ:

JHY03_09510

STSG:

B6R96_28620

STHU:

M1P56_09355

STRQ:

CGL27_38405

SSEC:

ABZO29_36565

SHUG:

ABVG11_07525

STRK:

R2B38_05365

STJL:

ACE1OA_28730

STHP:

MQE23_36035

STRX:

A6E92_27570

STFR:

SFR_6199

STFD:

B1K54_07990

STCL:

CAC01_27025

STSM:

B9S66_03180

STFI:

WID27_31935

SCT:	SCAT_5298(pimA)

SCY:	SCATT_52950

KSK:	KSE_14510(pimA)

KAB:	B7C62_04170

KAU:	B6264_21640

KIT:	CFP65_1083

KIS:	HUT16_05925

KCH:	O1G21_31125

KCM:	ABWK59_28545

KNB:	ACF9IK_28470

KIC:	KCMC57_up08890

KPUR:

ACFCLZ_08530

STRI:

C7M71_028255

PPOD:

AB0761_08005

YIA:	LO772_28055

STRH:

GXP74_14040

ABRY:

NYE86_12200

AGLA:

OIE69_32020

AREV:

RVR_1152

LXL:	KDY119_01909(pimA) KDY119_02514 KDY119_02788

PSIC:

J4E96_11615

PPHP:

VTA80_19935

MRG:	SM116_00285

CURT:

LCG91_02640

AMAV:

GCM10025877_14610

BCV:

Bcav_1983

BSAU:

DWV08_15380

JDE:	Jden_0448 Jden_1374

KSE:	Ksed_15390

DNI:	HX89_06780

DAY:	FV141_06120 FV141_09830

DERM:

H7F30_11395

LMOI:

VV02_15090

YIM:	J5M86_03760 J5M86_08185

ALX:	LVQ62_11710

BEI:	GCM100_17460

XCE:

Xcel_1660

XYA:	ET471_14725

IVA:	Isova_1661

IDO:	I598_0528(pimA_1)

IHA:	UQW22_14110

CET:	B8281_13660

CCEU:

CBR64_17960

CPRT:

FIC82_012505

PROU:

AB1046_06620

PROZ:

ACO229_05110

SKE:	Sked_05020 Sked_17450

SANW:

G7063_08220

SBIL:

SANBI_000478 SANBI_001691

CFL:

Cfla_1787

CFI:

Celf_2038

CGA:	Celgi_1573

CEZ:	CBP52_00815 CBP52_05305

CELZ:

E5225_08975

CEJ:	GC089_09370

CELH:

GXP71_07115

CIRA:

LFM56_09310

CPAL:

F1D97_07675 F1D97_12170

CELC:

K5O09_03875 K5O09_04870 K5O09_10345

CDON:

KKR89_08830

CWAN:

KG103_09095

CFEN:

KG102_09600

CWN:	NP075_09340

CCHE:

NP064_03995 NP064_07705 NP064_08470

CXIE:

NP048_09060

CELE:

P9841_00775 P9841_05340 P9841_06370

CELN:

CELD12_10140(pimA) CELD12_17830

OEK:	FFI11_014075

PSEI:

GCE65_07260

PSEK:

GCM125_27640

ICA:	Intca_1864

JTE:	ASJ30_07240

JLI:	EXU32_06395

JME:	EEW87_007875

JAY:	H7A72_07285

JCR:	O9K63_04290

JAI:	V1351_07810

JTR:	V3C34_10305

TEH:	GKE56_05220

PHW:	G7075_06040

PEI:	H9L10_06330

TED:	U5C87_15115

KNO:	V6K52_10935

ORN:	DV701_03360

ORZ:	FNH13_10140

OCP:	NF557_01320 NF557_08255

OFA:	NF556_10295

DCO:	SAMEA4475696_1639(pimA)

AUS:	IPK37_16990

HALT:

IM660_10060

RHAL:

LQF10_09735

RSUA:

LQF12_08540

DEM:	LGT36_004575 LGT36_013815

DSS:	GCM25873_07130 GCM25873_24690

DCP:	RN607_06435 RN607_12605

GEZ:	FE251_08345

GYU:	FE374_08810

GEW:	MF406_09655

CGRN:

4412665_01260(pimA)

PFR:	PFREUD_12400(pimA)

PFRE:

RM25_0951

PACD:

EGX94_01020

PAUS:

NCTC13651_01031(pimA)

PBO:	PACID_16560(pimA)

AACI:

ASQ49_13255

ACIJ:

JS278_01751(pimA)

AJI:	C0Z10_05935

MPH:	MLP_23770(pimA)

MIK:	FOE78_12865

MICG:

GJV80_08155

TFL:	RPIT_05705

TFA:	BW733_17160

TES:	BW730_05300

TEZ:	BKM78_00515

TDF:	H9L22_05680

TLA:	TLA_TLA_00105(pimA)

TEJ:	KDB89_07580

TLS:	QH948_06585

RAIN:

Rai3103_09620

PROP:

QQ658_06950

BROO:

brsh051_01230

AFUV:

AADG42_11100

NDK:	I601_0099(pimA_1)

NMES:

H9L09_18895

NPS:	KRR39_06230

MUZ:	H4N58_08875

MQR:	AB3M34_10010

SGRG:

L0C25_20010

NBT:	KLP28_00370

KFL:

Kfla_3368

KQI:	F1D05_05320

KSL:	OG809_30485

KRI:	OX958_17920

TFU:

Tfu_2101

THAO:

NI17_012905

TALX:

FOF52_10400

NDA:

Ndas_0821

NAL:	B005_3737(pimA)

NGV:	CDO52_19305

NEX:	NE857_11160

NAKE:

KGD83_21505

NCG:	KGD84_23320

NOCB:

UIS43_25850

STRR:

EKD16_16760(pimA)

SNAH:

OUQ99_23100

SAIU:

J4H86_25575

TCU:

Tcur_2102

ACTW:

F7P10_40150

AGRA:

AGRA3207_000752

AMAZ:

LUW76_48025

ACIR:

OG979_41830

AWS:	ACN3XK_34470 ACN3XK_35085

SPIQ:

OHA34_00685

ACTQ:

OG417_26855

SRO:

Sros_6124

NOA:	BKM31_04655

NOW:	GBF35_33745

NCX:	Nocox_27555(pimA)

NGN:	LCN96_36960

NFS:	OIE67_11645

TBI:

Tbis_2072

MHAI:

OHB01_35175

FRA:	Francci3_1364

FAL:

FRAAL2134

FRE:	Franean1_5152

FSY:	FsymDg_2557

FRI:	FraEuI1c_2323

ACE:

Acel_1353

NML:

Namu_3418

NAK:	EH165_05740

NAKA:

H7F38_14725

GOB:

Gobs_3184

BSD:	BLASA_2318(pimA)

BLAP:

MVA48_05455

BBRG:

U6N30_12180 U6N30_12185

BMON:

ABDB74_08360

MMAR:

MODMU_3364(pimA)

MOM:	KUM42_19090

KRA:

Krad_3062

SVI:	Svir_14970

SACC:

EYD13_08535(pimA2)

AMD:

AMED_5322

AMN:

RAM_27110

AMM:

AMES_5259

AMZ:

B737_5259

AOI:	AORI_4444(pimA)

AJA:	AJAP_16575(pimA)

AMQ:	AMETH_2863

AMYC:

CU254_21640

AMYB:

BKN51_09605

AAB:	A4R43_04190

AMYY:

YIM_17345(pimA2)

AORI:

SD37_22790

AACD:

LWP59_14185

APRT:

MUY14_16770

AROO:

NQK81_43670

ATHM:

L1857_17185

ARHD:

VSH64_15515

AMOG:

QRX60_40850

ACYN:

ORV05_21085

ACOR:

LCL61_22065

AMYZ:

HUW46_07646(pimA)

ACAB:

QRX50_29965

ANW:	QP939_37200

AMYD:

K1T34_47505

ABAR:

AMYBAR_002509

AMYE:

MJQ72_21390

AMYS:

CVV72_06035

ARHI:

AB5I40_00835

PDX:

Psed_3609

PSEA:

WY02_04355

PSEH:

XF36_11805

PSEQ:

AD006_16425

PECQ:

AD017_24260

PHH:	AFB00_28690

PAUT:

Pdca_30590

PBRO:

HOP40_23410

PPEL:

H6H00_22105

PSDS:

K1T35_22025

PALQ:

PaSha_22100

APRE:

CNX65_10675

AMI:

Amir_2094

SESP:

BN6_30330(pimA)

SSYI:

EKG83_34945

SACX:

IOD16_21550

KAL:

KALB_2451

KUT:	JJ691_46260

KBR:	Q4V65_10295

KPHY:

AOZ06_37115

LED:	BBK82_27085

LXR:	ACRSBM_09420

AHM:	TL08_10355

ACTI:

UA75_10860

ACAD:

UA74_10775

AHG:	AHOG_10110(pimA1)

ACTA:

C1701_03650

ACAU:

ACOJVX_07705

ALO:

CRK58133

PMAD:

BAY61_20435

ACTU:

Actkin_01957(pimA_1)

AAUR:

V5P93_005599

CROS:

N8J89_29120

ACTY:

OG774_08670

UME:	RM788_11080

STP:	Strop_1788

SAQ:

Sare_1775

MAU:	Micau_2257

MIL:

ML5_2369

MICB:

MicB006_5325

MTUA:

CSH63_13460

MICH:

FJK98_10595

MTEM:

GCE86_04730

MCAB:

HXZ27_11695

MSAG:

GCM10017556_46020

VMA:	VAB18032_14530

MCRA:

ID554_02500

VER:	HUT12_10625

MENO:

Jiend_07500

MCHL:

PVK74_02095

MFEU:

H1D33_17340

MPRN:

Q3V37_27130

MHAW:

RMN56_00765

MCAY:

PVK37_17280

MICF:

QQG74_11525

MICN:

WHN02_13525

VET:	ACQVFL_09960

ASE:

ACPL_6545

AMS:	AMIS_62880

ACTN:

L083_6074 L083_7331

ACTS:

ACWT_6414

AIH:	Aiant_22440

ACTR:

Asp14428_71350

ACTL:

L3i22_088230

ASIC:

Q0Z83_107020

AOU:	ACTOB_006811

ACTE:

ACTI_03130

AFS:

AFR_31105

PLK:	CIK06_11250

PLAB:

C6361_23580

PLAT:

C6W10_32460

PFLA:

Pflav_006090 Pflav_043290 Pflav_084150

PSUU:

Psuf_046800 Psuf_062980

ATL:	Athai_27560

ASER:

Asera_47250

PRY:	Prubr_48440

CATI:

CS0771_36200

DVC:	Dvina_42390

DMAT:

Dmats_37065

DFU:	Dfulv_37220

DROS:

Drose_27970

DAUR:

Daura_41085

DACT:

KZZ52_48535

NHY:	JQS43_11965

CCAZ:

COUCH_13045

CAI:

Caci_2345

SNA:

Snas_2407

NAV:	JQS30_09340

GLY:	K3N28_01210

AHE:

Arch_0816

ARCA:

HC352_03865

APHO:

JTE88_04105

APII:

NG665_04080

AWL:	P8A24_04960

ACAS:

P7079_04505

TPY:	CQ11_00845

TPYO:

X956_05995

TBW:	NCTC13354_00166(pimA_1)

TPEC:

HLG82_05145

TBER:

QPC17_04040

ASG:	FB03_01555

AUU:	CJ184_007560

ATIM:

CYJ17_0007475

ACTT:

DDD63_06640

AMY:	ADJ76_02635

SOO:	FBF35_05905

ACQ:	AM609_07185

AOS:	AXE84_10565

ARD:	AXF14_10130

ACTP:

B6G06_04090

ACTC:

CHIBA101_1366

ACTO:

C3V41_04200

ANE:	ATCC27039_10490

AHW:	NCTC11636_00266(pimA)

ACTZ:

CWT12_06050

AIR:	AIF0345_1563(pimA)

ASLA:

NCTC11923_02016(pimA_1)

AVC:	NCTC10951_00667(pimA_1)

AWE:	JG540_04855

AMAM:

HPC72_05635

AREP:

ID810_05830

AGH:	M3I41_04170

AMAS:

QU670_09035

ACAP:

MANAM107_23310

AUO:	R3I39_08840

ALIL:

D5R93_06175

ACTH:

JJJ15_01585

ACHN:

JJJ14_06890

AVU:	BK816_04570

FSL:	EJO69_01925

FLH:	EJ997_02985

WIK:	H8R18_04135

WNE:	PIG85_05760

GEU:	CJ185_004230

GHM:	CJ187_003475

VCB:	CYK25_004305

PHON:

BH719_01270

SAPP:

SAC06_05890

BFY:	ABYF36_08395

BLA:	BLA_0946(pimA) BLA_1345

BLC:	Balac_0824 Balac_1101

BLT:	Balat_0824 Balat_1101

BBB:	BIF_00971 BIF_01831

BBC:	BLC1_0788 BLC1_1057

BNM:	BALAC2494_00144 BALAC2494_00298

BLV:	BalV_0795 BalV_1061

BLW:	W7Y_0826 W7Y_1102

BLS:	W91_0846 W91_1127

BANI:

BL12_04120 BL12_05490

BANL:

BLAC_04220 BLAC_05545

BNI:	BANAN_04070 BANAN_05420

BANM:

EN10_04175 EN10_05580

BDE:

BDP_1179

BDN:

BBDE_1125

BAST:

BAST_0796 BAST_0972

BTP:	D805_0739 D805_1057

BCOR:

BCOR_0682 BCOR_0827

BII:	BINDI_0623 BINDI_0767

BPSP:

AH67_04445

BACT:

AB656_01400 AB656_02215

BCHO:

BcFMB_07280 BcFMB_08500

BSUE:

BS3272_04740

BAQK:

QN215_04495 QN215_05045

BFK:	QN062_01385 QN062_02595

SIJ:	SCIP_0503 SCIP_0672

PDO:

PSDT_0809

BAPK:

KIMH_05550(pimA) KIMH_07990

BNK:	KIM372_07680(pimA) KIM372_09520

PLAN:

A1s21148_03920

PLAK:

A1s21155_03735

PLIM:

PHILAsVB114_03140

PSUF:

A1sIA56_03640

PVS:	A1sIA79_03545

PVN:	A7sIIA15_03285

ABAM:

B1s21122_02975

NHI:	B1s21160_02850

NAB:	B1sIIB91_02670

EKE:	EK0264_01355

JTL:	M6D93_10895

JCY:	M6B22_20400

JAT:	SAMN05892883_3457

ABAI:

IMCC26256_11980

RXY:

Rxyl_2620

RRD:	RradSPS_0381

BSOL:

FSW04_23180

CWO:

Cwoe_1613

AFO:

Afer_1223

AYM:	YM304_19780(pimA)

ATQ:	GH723_08520

AQZ:	KSP35_03025

ADAE:

ACE2AJ_02625

IAM:	HC251_13915

IMA:	PO878_09545

DHI:	LH044_01095

AHAI:

AB8619_09565 AB8619_17640

TOI:	HG267_21735

TOZ:	HGR01_32790

DET:

DET0978

DEH:

cbdbA942

DEB:	DehaBAV1_0869

DEV:

DhcVS_851

DEG:	DehalGT_0822

DMC:

btf_927

DMD:

dcmb_913

DMG:

GY50_0860

DMX:	X792_04460

DMY:	X793_04620

DMZ:	X794_04250

DUC:	UCH007_08170

DLY:	Dehly_0527

DEW:	DGWBC_1103

DFO:	Dform_01206(pimA)

DETH:

HX448_07365

DLF:	V8247_07310

LMAJ:

GKN94_11490

HAU:	Haur_4328 Haur_4807

CALL:

OZ401_003843

TTR:

Tter_1866

TBH:	Tbon_02390

TFLA:

O0235_11345

THUG:

KNN16_12560

CAQA:

MICH65_0065

MARW:

MNSC_05210

» show all

Reference

1 [PMID:12068013]

Authors

Kordulakova J, Gilleron M, Mikusova K, Puzo G, Brennan PJ, Gicquel B, Jackson M

Title

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria.

Journal

J Biol Chem 277:31335-44 (2002)
DOI:10.1074/jbc.M204060200

Sequence

[mtu:Rv2610c]

Reference

2 [PMID:15939292]

Authors

Gu X, Chen M, Wang Q, Zhang M, Wang B, Wang H

Title

Expression and purification of a functionally active recombinant GDP-mannosyltransferase (PimA) from Mycobacterium tuberculosis H37Rv.

Journal

Protein Expr Purif 42:47-53 (2005)
DOI:10.1016/j.pep.2005.03.015

Sequence

[mtu:Rv2610c]

Reference

3 [PMID:25402770]

Authors

Giganti D, Albesa-Jove D, Urresti S, Rodrigo-Unzueta A, Martinez MA, Comino N, Barilone N, Bellinzoni M, Chenal A, Guerin ME, Alzari PM

Title

Secondary structure reshuffling modulates glycosyltransferase function at the membrane.

Journal

Nat Chem Biol 11:16-8 (2015)
DOI:10.1038/nchembio.1694

Sequence

[msm:MSMEG_2935]

Reference

4 [PMID:27189944]

Authors

Rodrigo-Unzueta A, Martinez MA, Comino N, Alzari PM, Chenal A, Guerin ME

Title

Molecular Basis of Membrane Association by the Phosphatidylinositol Mannosyltransferase PimA Enzyme from Mycobacteria.

Journal

J Biol Chem 291:13955-63 (2016)
DOI:10.1074/jbc.M116.723676

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.345

IUBMB Enzyme Nomenclature:

2.4.1.345

ExPASy - ENZYME nomenclature database:

2.4.1.345

BRENDA, the Enzyme Database:

2.4.1.345

All links

Gene (6111)   
   MGENES (5439)   
   RefGene (672)   
Protein sequence (1071)   
   UniProt (1007)   
   SWISS-PROT (6)   
   RefSeq(pep) (58)   
DNA sequence (8576)   
   RefSeq(nuc) (7098)   
   GenBank (897)   
   EMBL (581)   
All databases (15758)   

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