KEGG   ENZYME: 2.4.1.362
Entry
EC 2.4.1.362                Enzyme                                 

Name
alpha-(1->3) branching sucrase;
branching sucrase A;
BRS-A;
brsA (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
sucrose:(1->6)-alpha-D-glucan 3-alpha-D-[(1->3)-alpha-D-glucosyl]-transferase
Reaction(IUBMB)
sucrose + a (1->6)-alpha-D-glucan = D-fructose + a (1->6)-alpha-D-glucan containing a (1->3)-alpha-D-glucose branch [RN:R12349]
Reaction(KEGG)
R12349
Substrate
sucrose [CPD:C00089];
(1->6)-alpha-D-glucan
Product
D-fructose [CPD:C00095];
(1->6)-alpha-D-glucan containing a (1->3)-alpha-D-glucose branch [CPD:C22097]
Comment
The enzyme from Leuconostoc spp. is responsible for producing alpha-(1->3) branches in alpha-(1->6) glucans by transferring the glucose residue from fructose to a 3-hydroxyl group of a glucan.
History
EC 2.4.1.362 created 2019
Orthology
K23396  alpha-(1->3) branching sucrase
Reference
1  [PMID:26763236]
  Authors
Vuillemin M, Claverie M, Brison Y, Severac E, Bondy P, Morel S, Monsan P, Moulis C, Remaud-Simeon M
  Title
Characterization of the First alpha-(1-->3) Branching Sucrases of the GH70 Family.
  Journal
J Biol Chem 291:7687-702 (2016)
DOI:10.1074/jbc.M115.688044
  Sequence
Reference
2  [PMID:27141938]
  Authors
Moulis C, Andre I, Remaud-Simeon M
  Title
GH13 amylosucrases and GH70 branching sucrases, atypical enzymes in their respective families.
  Journal
Cell Mol Life Sci 73:2661-79 (2016)
DOI:10.1007/s00018-016-2244-8
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.362
IUBMB Enzyme Nomenclature: 2.4.1.362
ExPASy - ENZYME nomenclature database: 2.4.1.362
BRENDA, the Enzyme Database: 2.4.1.362

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