KEGG   ENZYME: 2.4.1.365Help
Entry
EC 2.4.1.365                Enzyme                                 

Name
protopanaxadiol-type ginsenoside-3-O-glucoside 2''-O-glucosyltransferase;
UGT94Q2 (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:3-O-glucosyl-protopanaxadiol-type ginsenoside 2''-O-glucosyltransferase
Reaction(IUBMB)
(1) UDP-alpha-D-glucose + (20S)-ginsenoside Rh2 = UDP + (20S)-ginsenoside Rg3 [RN:R12385];
(2) UDP-alpha-D-glucose + ginsenoside F2 = UDP + ginsenoside Rd [RN:R12386]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:C00029];
(20S)-ginsenoside Rh2 [CPD:C22128];
ginsenoside F2 [CPD:C20779]
Product
UDP [CPD:C00015];
(20S)-ginsenoside Rg3;
ginsenoside Rd [CPD:C20725]
Comment
The enzyme, characterized from the plant Panax ginseng, transfers a glucosyl moiety to the 2'' position of the glucose moiety in the protopanaxadiol-type ginsenoside-3-O-glucosides (20S)-ginsenoside Rh2 and ginsenoside F2.
History
EC 2.4.1.365 created 2019
Orthology
K23522  protopanaxadiol-type ginsenoside-3-O-glucoside 2''-O-glucosyltransferase
Reference
1  [PMID:25320211]
  Authors
Jung SC, Kim W, Park SC, Jeong J, Park MK, Lim S, Lee Y, Im WT, Lee JH, Choi G, Kim SC
  Title
Two ginseng UDP-glycosyltransferases synthesize ginsenoside Rg3 and Rd.
  Journal
Plant Cell Physiol 55:2177-88 (2014)
DOI:10.1093/pcp/pcu147
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.365
IUBMB Enzyme Nomenclature: 2.4.1.365
ExPASy - ENZYME nomenclature database: 2.4.1.365
BRENDA, the Enzyme Database: 2.4.1.365

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