KEGG   ENZYME: 2.4.1.377
Entry
EC 2.4.1.377                Enzyme                                 
Name
dTDP-Rha:alpha-D-Gal-diphosphoundecaprenol alpha-1,3-rhamnosyltransferase;
wbaN (gene name);
rfbN (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
dTDP-beta-L-rhamnose:alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-rhamnosyltransferase (configuration-inverting)
Reaction(IUBMB)
dTDP-beta-L-rhamnose + alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol = dTDP + alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und [RN:R12739]
Reaction(KEGG)
R12739(G)
Substrate
dTDP-beta-L-rhamnose [CPD:C03319];
alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol
Product
dTDP [CPD:C00363];
alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und
Comment
The enzyme, characterized from several Salmonella strains, participates in the biosynthesis of the repeat unit of O antigens produced by strains that belong to the A, B, D and E groups.
History
EC 2.4.1.377 created 2021
Orthology
K12992  O-antigen biosynthesis alpha-1,3-rhamnosyltransferase
Genes
STYSTY2294(rfbN)
STTt0788(rfbN)
SEXSTBHUCCB_8400
SENTTY21A_03995
STMSTM2085(rfbN)
SEOSTM14_2579(rfbN)
SEVSTMMW_21161
SEYSL1344_2062(rfbN)
SEMSTMDT12_C21070
SEJSTMUK_2115(rfbN)
SEBSTM474_2170(rfbN)
SEFUMN798_2253(rfbN)
SETUSTU288_06810
SETCCFSAN001921_06360
SENRSTMDT2_20591(rfbN)
SENDDT104_21441(rfbN)
SENICY43_11250
SEENSE451236_16635
SPTSPA0786(rfbN)
SEKSSPA0736
SPQSPAB_00946
SEHSeHA_C2311
SHBSU5_02679
SENHCFSAN002069_21395
SEEHSEEH1578_19705
SEWSeSA_A2313
SEASeAg_B2210
SENSQ786_10295
SEDSeD_A2424
SEGSG2115(rfbN)
SELSPUL_0813(rfbN)
SEGASPUCDC_0813(rfbN)
SETSEN2084(rfbN)
SENAAU38_10515
SENOAU37_10525
SENVAU39_10525
SENQAU40_11780
SENLIY59_10810
SENJCFSAN001992_01005
SEEPI137_03655
KIENCTC12125_00633
PAKHB0X70_24685
PLUICE143_24725
PCAMHNE05_08240
MESLKKZ03_09535
AELNCTC12917_02814
TAUTola_2045
CDIZCEDIAZO_02901
RAPRHOA_2855(rfbN)
PMUOLOK61_15930
 » show all
Reference
1  [PMID:7684736]
  Authors
Liu D, Haase AM, Lindqvist L, Lindberg AA, Reeves PR.
  Title
Glycosyl transferases of O-antigen biosynthesis in Salmonella enterica: identification and characterization of transferase genes of groups B, C2, and E1.
  Journal
J Bacteriol 175:3408-13 (1993)
DOI:10.1128/JB.175.11.3408-3413.1993
  Sequence
[stm:STM2085]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.377
IUBMB Enzyme Nomenclature: 2.4.1.377
ExPASy - ENZYME nomenclature database: 2.4.1.377
BRENDA, the Enzyme Database: 2.4.1.377

DBGET integrated database retrieval system