KEGG   ENZYME: 2.4.1.382
Entry
EC 2.4.1.382                Enzyme                                 
Name
CDP-abequose:alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und alpha-1,3-abequosyltransferase;
wbaR (gene name);
rfbR (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
CDP-alpha-D-abequose:2-O-acetyl-alpha-L-rhamnopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-alpha-D-galactopyranosyl-diphospho-ditrans,octacis-undecaprenol 3IV-alpha-abequosyltransferase (configuration retaining)
Reaction(IUBMB)
CDP-alpha-D-abequose + 2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und = CDP + alpha-D-Abe-(1->3)-2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und [RN:R12744]
Reaction(KEGG)
R12744(G)
Substrate
CDP-alpha-D-abequose [CPD:C01788];
2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und
Product
CDP [CPD:C00112];
alpha-D-Abe-(1->3)-2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und
Comment
The enzyme, present in Salmonella strains that belong to group C2, participates in the biosynthesis of the repeat unit of O antigens produced by these strains.
History
EC 2.4.1.382 created 2021
Orthology
K25199  O-antigen biosynthesis alpha-1,3-abequosyltransferase
Genes
SEESNSL254_A2269
SENNSN31241_31930
SENBBN855_21760
SAVIJYB87_13125
Reference
1  [PMID:7541787]
  Authors
Liu D, Lindqvist L, Reeves PR
  Title
Transferases of O-antigen biosynthesis in Salmonella enterica: dideoxyhexosyltransferases of groups B and C2 and acetyltransferase of group C2.
  Journal
J Bacteriol 177:4084-8 (1995)
DOI:10.1128/JB.177.14.4084-4088.1995
  Sequence
Reference
2  [PMID:28929089]
  Authors
Zhao X, Dai Q, Jia R, Zhu D, Liu M, Wang M, Chen S, Sun K, Yang Q, Wu Y, Cheng A.
  Title
Two Novel Salmonella Bivalent Vaccines Confer Dual Protection against Two Salmonella Serovars in Mice.
  Journal
Front Cell Infect Microbiol 7:391 (2017)
DOI:10.3389/fcimb.2017.00391
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.382
IUBMB Enzyme Nomenclature: 2.4.1.382
ExPASy - ENZYME nomenclature database: 2.4.1.382
BRENDA, the Enzyme Database: 2.4.1.382

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