KEGG   ENZYME: 2.4.1.5
Entry
EC 2.4.1.5                  Enzyme                                 

Name
dextransucrase;
sucrose 6-glucosyltransferase;
SGE;
CEP;
sucrose-1,6-alpha-glucan glucosyltransferase;
sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
sucrose:(1->6)-alpha-D-glucan 6-alpha-D-glucosyltransferase
Reaction(IUBMB)
sucrose + [(1->6)-alpha-D-glucosyl]n = D-fructose + [(1->6)-alpha-D-glucosyl]n+1 [RN:R02120 R06066]
Reaction(KEGG)
R02120 R06066(G)
Substrate
sucrose [CPD:C00089];
[(1->6)-alpha-D-glucosyl]n
Product
D-fructose [CPD:C00095];
[(1->6)-alpha-D-glucosyl]n+1
Comment
The glucansucrases transfer a D-glucosyl residue from sucrose to a glucan chain. They are classified based on the linkage by which they attach the transferred residue. In some cases, in which the enzyme forms more than one linkage type, classification relies on the relative proportion of the linkages that are generated. This enzyme extends the glucan chain by an alpha(1->6) linkage.
History
EC 2.4.1.5 created 1961
Pathway
ec00500  Starch and sucrose metabolism
ec01100  Metabolic pathways
Orthology
K00689  dextransucrase
Genes
LLM: llmg_0458
SMU: SMU_1004(gtfB) SMU_1005(gtfC) SMU_910(gtfD)
SMC: SmuNN2025_1017(gtfC) SmuNN2025_1018(gtfB) SmuNN2025_1113(gtfD)
SMUT: SMUGS5_04025 SMUGS5_04450 SMUGS5_04455
SMJ: SMULJ23_1026(gtfC) SMULJ23_1027(gtfB) SMULJ23_1111(gtfD)
SMUA: SMUFR_0792 SMUFR_0875 SMUFR_0876
SSA: SSA_0613(gtfP)
SGO: SGO_0497(gtfG)
SGA: GALLO_1055(gtfA) GALLO_1057(gtfB)
SGG: SGGBAA2069_c10400(gtfB) SGGBAA2069_c10420(gtfB1)
SGT: SGGB_1044(gtfA) SGGB_1046(gtfB)
SOR: SOR_1347
SIF: Sinf_0877(gtfA)
STRG: SRT_10260(gtfC) SRT_10270(gtfB) SRT_11870(gtfD)
OOE: OEOE_0544
LME: LEUM_1752
LMM: MI1_07585
LMK: LMES_1520
LKI: LKI_09980
LGS: LEGAS_1012(dsrA)
 » show all
Reference
1  [PMID:13651133]
  Authors
BAILEY RW.
  Title
Transglucosidase activity of rumen strains of Streptococcus bovis. 2. Isolation and properties of dextransucrase.
  Journal
Biochem J 72:42-9 (1959)
DOI:10.1042/bj0720042
Reference
2
  Authors
Bailey, R.W., Barker, S.A., Bourne, E.J. and Stacey, M.
  Title
Immunopolysaccharides. Part VI. The isolation and properties of the dextransucrase of Betacoccus arabinosaceous.
  Journal
J Chem Soc (Lond) 3530-3536 (1957)
Reference
3  [PMID:24540594]
  Authors
HEHRE EJ
  Title
Enzymic synthesis of polysaccharides: a biological type of polymerization.
  Journal
Adv Enzymol Relat Subj Biochem 11:297-337 (1951)
DOI:10.1002/9780470122563.ch6
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.5
IUBMB Enzyme Nomenclature: 2.4.1.5
ExPASy - ENZYME nomenclature database: 2.4.1.5
BRENDA, the Enzyme Database: 2.4.1.5
CAS: 9032-14-8

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