KEGG   ENZYME: 2.4.1.56Help
Entry
EC 2.4.1.56                 Enzyme                                 

Name
lipopolysaccharide N-acetylglucosaminyltransferase;
UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase;
uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase;
UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-alpha-D-glucosaminyllipopolysaccharide [RN:R01996]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
lipopolysaccharide [CPD:C00338]
Product
UDP [CPD:C00015];
N-acetyl-alpha-D-glucosaminyllipopolysaccharide
Comment
Transfers N-acetylglucosaminyl residues to a D-galactose residue in the partially completed lipopolysaccharide core [cf. EC 2.4.1.44 (lipopolysaccharide 3-alpha-galactosyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].
History
EC 2.4.1.56 created 1972
Pathway
ec00540  Lipopolysaccharide biosynthesis
ec01100  Metabolic pathways
Orthology
K03280  UDP-N-acetylglucosamine:(glucosyl)LPS alpha-1,2-N-acetylglucosaminyltransferase
Genes
ECG: E2348C_3871
EFE: EFER_3912(rfaK)
EAL: EAKF1_ch2319
EMA: C1192_17515
STY: STY4081(waaK)
STT: t3805(waaK)
SEX: STBHUCCB_40160
SENT: TY21A_19330
STM: STM3714(rfaK)
SEO: STM14_4475(rfaK)
SEY: SL1344_3680(rfaK)
SEJ: STMUK_3700(rfaK)
SEB: STM474_3887(rfaK)
SEF: UMN798_4034(waaK)
SENI: CY43_19270
SPT: SPA3566(waaK)
SEK: SSPA3329(waaK)
SEI: SPC_3796(waaK)
SEC: SCH_3637(rfaK)
SHB: SU5_04191
SENS: Q786_18160
SED: SeD_A4100
SEG: SG3717(rfaK)
SEL: SPUL_3850(rfaK)
SEGA: SPUCDC_3836(rfaK)
SET: SEN3536(rfaK)
SENA: AU38_18060
SENO: AU37_18250
SENV: AU39_18255
SENQ: AU40_20340
SENL: IY59_18695
SEEP: I137_18470
SENE: IA1_18055
SBG: SBG_3296(waaK)
SBZ: A464_3791
CRO: ROD_41941(rfaK)
EBF: D782_0101
XPO: XPG1_3598(waaK)
PSX: DR96_1043
 » show all
Taxonomy
Reference
1  [PMID:5332855]
  Authors
Osborn MJ, D'Ari L.
  Title
Enzymatic incorporation of N-acetylglucosamine into cell wall lipopolysaccharide in a mutant strain of Salmonella typhimurium.
  Journal
Biochem Biophys Res Commun 16:568-75 (1964)
DOI:10.1016/0006-291X(64)90194-9
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.56
IUBMB Enzyme Nomenclature: 2.4.1.56
ExPASy - ENZYME nomenclature database: 2.4.1.56
BRENDA, the Enzyme Database: 2.4.1.56
CAS: 37277-64-8

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