Entry |
|
Name |
ceramide glucosyltransferase;
UDP-glucose:ceramide glucosyltransferase;
ceramide:UDP-Glc glucosyltransferase;
uridine diphosphoglucose-ceramide glucosyltransferase;
ceramide:UDP-glucose glucosyltransferase;
glucosylceramide synthase;
UDP-glucose:N-acylsphingosine D-glucosyltransferase
|
Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
|
Sysname |
UDP-alpha-D-glucose:N-acylsphingosine beta-D-glucosyltransferase (configuration-inverting)
|
Reaction(IUBMB) |
UDP-alpha-D-glucose + an N-acylsphingosine = UDP + a beta-D-glucosyl-N-acylsphingosine [RN: R01497 R06275]
|
Reaction(KEGG) |
|
Substrate |
UDP-alpha-D-glucose [CPD: C00029];
N-acylsphingosine [CPD: C00195]
|
Product |
UDP [CPD: C00015];
beta-D-glucosyl-N-acylsphingosine [CPD: C01190]
|
Comment |
Sphingosine and dihydrosphingosine can also act as acceptors; CDP-glucose can act as donor.
|
History |
EC 2.4.1.80 created 1976
|
Pathway |
|
Orthology |
K00720 | ceramide glucosyltransferase |
|
Genes |
PBG: | 122474780(UGCG) 122490230 |
LRUF: | 124503093 124528354 |
SCAM: | 104145320(UGCG) 104154078 |
XLA: | 399204(ugcg.L) 495444(ugcg.S) |
SANH: | 107658668 107685163 |
CCAR: | 109097720 109097723 |
CAUA: | 113054060 113109641 113109669 |
CGIB: | 127966256 128021528 |
MASI: | 127432812 127433320 |
MSAM: | 119906517 119914861(ugcg) |
PPRL: | 129356197 129356952 |
SASA: | 106568572 106572764 |
STRU: | 115149531 115160183 |
OTW: | 112219878 112257307(ugcg) |
OMY: | 110523078 110536868(ugcg) |
OGO: | 123989571 124000381 124029770 |
OKE: | 118379804 127906493(ugcg) |
SALP: | 111957369 112069012(ugcg) |
SNH: | 120026327 120042623(ugcg) |
CCLU: | 121573357 121583630 |
AANG: | 118206309 118212656(ugcg) |
PSPA: | 121303343 121314728 |
ARUT: | 117408820 117411687 |
PMRN: | 116942936 116948750(UGCG) |
LRJ: | 133345219(UGCG) 133359061 133359152 |
SCLV: | 120326318 120334856 |
APLC: | 110977427 110980457 110980461 |
DSI: | Dsimw501_GD11642(Dsim_GD11642) |
DMN: | 108160483 117192533 117192534 117193519 |
CQU: | CpipJ_CPIJ005214 CpipJ_CPIJ019694 |
CSET: | 123312046 123321321 |
ACOO: | 126837464 126841576 |
BROR: | 134529382 134533542 |
LPOL: | 106466956 106474689 |
CEL: | CELE_F20B4.6(cgt-2) CELE_F59G1.1(cgt-3) CELE_T06C12.10(cgt-1) |
CBR: | CBG_02537(Cbr-cgt-3) CBG_08882 |
CRQ: | GCK72_006150 GCK72_022423 |
LGI: | LOTGIDRAFT_120942 LOTGIDRAFT_214304 LOTGIDRAFT_235024 |
PVUL: | 126819221 126819713 126824738 |
PCAN: | 112554206 112561786 112569428 |
GAE: | 121367878 121375754 121380197 |
HRF: | 124133431 124134112 124135586 |
HRJ: | 124256637 124260052 124289638 |
CANU: | 128176372 128188471 |
CVN: | 111130733 111131692 111135173 |
MYI: | 110443688 110449605 110451185 |
PMAX: | 117325759 117332702 117335232 |
MCAF: | 127712674 127722309 |
MMER: | 123523110 123525546 123533580 |
RPHI: | 132739590 132754789 |
DPOL: | 127844479 127852326 127871542 127871555 |
MAEA: | 128213826 128227773 128227940 128231207 |
SMM: | Smp_157080 Smp_160210 |
LLON: | 135482443 135485881 |
LBG: | 92210201(LODBEIA_P50050) |
CAL: | CAALFM_C402010CA(HSX11) |
YLI: | 2907264(YALI2_C00891g) |
NTE: | NEUTE1DRAFT57926(NEUTE1DRAFT_57926) |
SMP: | 10807098(SMAC4_03191) |
PBEL: | QC761_207510(HSX11) |
PPSD: | QC762_207510(HSX11_3) |
PPSP: | QC763_207510(HSX11_2) |
PPSA: | QC764_0074190(HSX11_1) QC764_207510(HSX11_2) |
FPOA: | FPOAC1_008917(GCS1_2) |
FMU: | J7337_006621(GCS1_2) |
TATV: | 25785317(TrAtP1_011704) |
TASP: | 36608260(TrAFT101_008420) |
PLJ: | 28890401(PLICBS_009734) |
PTKZ: | JDV02_004819(HSX11) |
PTRR: | 6349324(PtrM4_133110) |
CDEP: | 91089824(L203_105615) |
KMG: | 30162353(I203_100900) |
KNE: | 92179385(IAR55_002126) |
CCAC: | CcaHIS019_0608420(HSX11) |
ABP: | AGABI1DRAFT67520(AGABI1DRAFT_67520) |
ABV: | AGABI2DRAFT61534(AGABI2DRAFT_61534) |
SCM: | SCHCO_02684563(SCHCODRAFT_02684563) |
PGR: | PGTG_20281 PGTG_21479 |
XPH: | XppCFBP6546_19555(XppCFBP6546P_19555) |
REH: | H16_B2171(h16_B2171) |
BML: | BMA10229_A2073 BMA10229_A2853(hpnI) |
BMN: | BMA10247_1749(hpnI) BMA10247_3328 |
BMAE: | DM78_1174 DM78_2820 |
BMAI: | DM57_2003 DM57_2596 |
BPM: | BURPS1710b_0488 BURPS1710b_2860 |
BPL: | BURPS1106A_0308 BURPS1106A_2797 |
BPD: | BURPS668_0294 BURPS668_2738 |
BPR: | GBP346_A0212(hpnI_1) GBP346_A2918(hpnI_2) |
BPZ: | BP1026B_I0924 BP1026B_I3219 |
BPQ: | BPC006_I0290 BPC006_I2836 |
BUU: | WS70_05715 WS70_15995 |
BSAV: | WS86_06495 WS86_17655 |
BHG: | I6G56_02930(hpnI) I6G56_14205(hpnI) |
BUD: | AQ610_06280 AQ610_17205 |
BVI: | Bcep1808_1089 Bcep1808_4730 |
BUR: | Bcep18194_A4282 Bcep18194_B0471 |
BCEN: | DM39_1016 DM39_5445 |
BAC: | BamMC406_1052 BamMC406_5080 |
BCEP: | APZ15_09570 APZ15_22415 |
BPYR: | ABD05_11480 ABD05_23645 |
BCON: | NL30_00430 NL30_09785 |
BDF: | WI26_05380 WI26_24780 |
BTEI: | WS51_08975 WS51_16120 |
BSEM: | WJ12_05745 WJ12_31945 |
BPSL: | WS57_02115 WS57_23435 |
BMEC: | WJ16_05520 WJ16_30470 |
BSTL: | BBJ41_06240 BBJ41_25900 |
BANN: | JFN94_05690(hpnI) JFN94_29855(hpnI) |
BARI: | NLX30_05975(hpnI) NLX30_25195(hpnI) |
BAEN: | L3V59_06265(hpnI) L3V59_26730(hpnI) |
BGL: | bglu_1g10000 bglu_2g03670 |
BUG: | BC1001_1561 BC1001_1566 |
BGD: | bgla_1g11350 bgla_2g17420 |
BUE: | BRPE67_ACDS23540 BRPE67_CCDS07270 |
BUQ: | AC233_31370 AC233_31395 |
BGP: | BGL_1c10340 BGL_2c04560(hpnI) |
BPLA: | bpln_1g09890 bpln_2g05110 |
BUM: | AXG89_23680 AXG89_23695 AXG89_28995 AXG89_29010 |
BUI: | AX768_19925 AX768_19940 |
BURK: | DM992_15710 DM992_23545 |
BXE: | Bxe_A2063 Bxe_A2068 Bxe_B0384 |
BXB: | DR64_4218 DR64_4223 DR64_5722 |
BGE: | BC1002_1626 BC1002_1632 |
BPX: | BUPH_02073 BUPH_02078 |
BPY: | Bphyt_2195 Bphyt_2200 |
BUZ: | AYM40_09220 AYM40_09245 AYM40_23060 |
PSPW: | BJG93_04260(hpnI) BJG93_04290(hpnI) |
PARA: | BTO02_04680 BTO02_32910 |
PARB: | CJU94_14335 CJU94_14360 CJU94_15730 CJU94_27530 |
PHS: | C2L64_07560 C2L64_20575 C2L64_46460 |
PTER: | C2L65_07285 C2L65_24755 |
PGP: | CUJ91_32255 CUJ91_32280 |
PCJ: | CUJ87_08175 CUJ87_08715 CUJ87_08740 |
PTS: | CUJ90_19770 CUJ90_19795 |
PMEG: | FNZ07_11175 FNZ07_20550 |
PTRO: | G5S35_09075 G5S35_24735 |
PACP: | FAZ97_08610 FAZ97_31630 |
PACS: | FAZ98_08505 FAZ98_33150 |
PEW: | KZJ38_18490(hpnI) KZJ38_35745(hpnI) |
PDIO: | PDMSB3_2273 PDMSB3_2278 PDMSB3_3061.1 |
PBRY: | NDK50_10960(hpnI) NDK50_10985(hpnI) |
PSAA: | QEN71_21470(hpnI) QEN71_31770(hpnI) QEN71_35030(hpnI) |
PKF: | RW095_07735(hpnI) RW095_28720(hpnI) RW095_28745(hpnI) |
PPAI: | E1956_08865 E1956_28805 |
PHUN: | U0042_04375(hpnI) U0042_12605(hpnI) |
CABA: | SBC2_19310 SBC2_49610 |
CABK: | NK8_42740(hpnI) NK8_44930(hpnI) |
TVL: | FAZ95_07315 FAZ95_27900 |
AGR: | AGROH133_06859(ugcG) |
MEA: | Mex_1p0541 Mex_1p3685 |
MZA: | B2G69_10335 B2G69_24830 |
MRD: | Mrad2831_0974 Mrad2831_3865 |
MOR: | MOC_1191(hpnI) MOC_4411 |
META: | Y590_02640 Y590_16965 |
MAQU: | Maq22A_c00115 Maq22A_c16025 |
MPHY: | MCBMB27_00569 MCBMB27_03340 |
MEE: | DA075_00125 DA075_31530 |
METD: | C0214_03125 C0214_18915 |
METX: | A3862_12140 A3862_25705 |
METS: | DK389_00135 DK389_19215 DK389_31850 |
METI: | DK427_11605 DK427_24670 |
MMES: | MMSR116_10400 MMSR116_26105 |
MTEA: | DK419_00175 DK419_17590 |
MIND: | mvi_13780 mvi_46390 |
MOG: | MMB17_13640(hpnI) MMB17_14680 |
MTAD: | M6G65_03875(hpnI) M6G65_27920 |
MSL: | Msil_0130 Msil_1502 Msil_3035 |
MTUN: | MTUNDRAET4_0180 MTUNDRAET4_3347 |
MLG: | CWB41_00755 CWB41_03155 |
MEDK: | QEV83_12670 QEV83_18590 |
BBAR: | RHAL1_00522 RHAL1_03937 |
HDN: | Hden_0483 Hden_0488 Hden_3051 |
HDT: | HYPDE_24918 HYPDE_24943 HYPDE_38423 |
HMC: | HYPMC_2933 HYPMC_3764 HYPMC_4291 |
MBRY: | B1812_09720 B1812_11620 B1812_14350 |
MROS: | EHO51_09750 EHO51_12335 |
MHEY: | H2LOC_001830 H2LOC_002890 H2LOC_016565 |
MPAR: | F7D14_02525 F7D14_10295 |
MIWA: | SS37A_30500 SS37A_33790 |
MESZ: | LNB28_12600 LNB28_15265 |
MTW: | CQW49_09025 CQW49_17480 |
MECQ: | MSC49_06450 MSC49_35850(ugcG) |
LIZ: | LGH83_02085 LGH83_18650(hpnI) |
LCK: | HN018_02130 HN018_06635 |
NAO: | Y958_22600 Y958_29210 |
GEC: | GEO60473_01510(hpnI) |
GBN: | GEOBRER4_08520(hpnI) |
DAO: | Desac_1010 Desac_1022 |
MSD: | MYSTI_00909 MYSTI_05254 |
MYM: | A176_002097 A176_006082 |
MFB: | MFUL124B02_05150 MFUL124B02_14125 MFUL124B02_28810 |
MYX: | QEG98_05195 QEG98_25875 |
MLAN: | JY572_00355 JY572_22015 |
CCX: | COCOR_00784 COCOR_01774 COCOR_02605(ugcG) |
MFU: | LILAB_04215 LILAB_31910 |
MMAS: | MYMAC_000923 MYMAC_004689 |
PPAK: | JY651_08145 JY651_34675 |
SUR: | STAUR_5634 STAUR_7076 |
AVM: | JQX13_07085 JQX13_34545 |
MBD: | MEBOL_004338 MEBOL_005947 |
CFUS: | CYFUS_001185 CYFUS_003454 |
MRM: | A7982_00107 A7982_03913 A7982_08937 |
SAMY: | DB32_003881 DB32_008060 |
STJ: | SALIVA_1338(FNV0895) |
SAUP: | NCTC3168_01774(FNV0895) |
SVF: | NCTC3166_00973(FNV0895) |
SYY: | SYNGTS_1546(slr0813) |
SYT: | SYNGTI_1546(slr0813) |
SYS: | SYNPCCN_1545(slr0813) |
SYQ: | SYNPCCP_1545(slr0813) |
CYN: | Cyan7425_1602 Cyan7425_5069 |
LEN: | LEP3755_41650 LEP3755_46880 |
KOV: | K9N68_09195 K9N68_19110 K9N68_21060(hpnI) |
LSC: | KIK02_08880(hpnI) KIK02_23265 |
OAC: | Oscil6304_5380 Oscil6304_5381 |
SCYT: | SAMD_46680 SAMD_46690 |
SCYS: | NIES4073_49430 NIES4073_49440 |
KBS: | EPA93_18675 EPA93_18680 |
UAM: | UABAM_00420 UABAM_00421 |
ABA: | Acid345_0723 Acid345_0724 |
ACA: | ACP_0805 ACP_1042 ACP_2005 |
ACM: | AciX9_0056 AciX9_0964 |
GMA: | AciX8_0165 AciX8_1675 |
GRW: | FTO74_00220 FTO74_01610 |
GRB: | GOB94_09400 GOB94_13755 |
TSA: | AciPR4_3023 AciPR4_4055 |
TRS: | Terro_0191 Terro_3566 |
TALB: | FTW19_03205 FTW19_20445 |
ABAS: | ACPOL_1039 ACPOL_1194 ACPOL_3979 |
EDA: | GWR55_14500 GWR55_18875 |
EDG: | H7846_01985(hpnI) H7846_14530 |
ADIN: | H7849_20685(hpnI) H7849_25090 |
TGI: | RBB81_03205 RBB81_04560(hpnI) RBB81_19375 |
TEMP: | RBB75_01820 RBB75_07185(hpnI) |
TPSC: | RBB77_02300(hpnI) RBB77_09225 |
SUS: | Acid_1399 Acid_1491 Acid_6450 |
PFER: | IRI77_19410(hpnI) IRI77_29800 |
CTM: | Cabther_A0245 Cabther_B0247 Cabther_B0595 |
CVL: | J8C06_12850(hpnI) J8C06_14795(hpnI) |
CHLO: | J8C02_11590(hpnI) J8C02_13905(hpnI) |
» show all
|
Reference |
|
Authors |
Basu S, Kaufman B, Roseman S. |
Title |
Enzymatic synthesis of glucocerebroside by a glucosyltransferase from embryonic chicken brain. |
Journal |
J Biol Chem 248:1388-94 (1973) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.4.1.80 |
ExPASy - ENZYME nomenclature database: | 2.4.1.80 |
|