| Entry |
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| Name |
dolichyl-phosphate beta-D-mannosyltransferase;
GDP-Man:DolP mannosyltransferase;
dolichyl mannosyl phosphate synthase;
dolichyl-phospho-mannose synthase;
GDP-mannose:dolichyl-phosphate mannosyltransferase;
guanosine diphosphomannose-dolichol phosphate mannosyltransferase;
dolichol phosphate mannose synthase;
dolichyl phosphate mannosyltransferase;
dolichyl-phosphate mannose synthase;
GDP-mannose-dolichol phosphate mannosyltransferase;
GDP-mannose-dolichylmonophosphate mannosyltransferase;
mannosylphosphodolichol synthase;
mannosylphosphoryldolichol synthase
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| Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
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| Sysname |
GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase
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| Reaction(IUBMB) |
GDP-alpha-D-mannose + dolichyl phosphate = GDP + dolichyl beta-D-mannosyl phosphate [RN: R01009]
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| Reaction(KEGG) |
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| Substrate |
GDP-alpha-D-mannose [CPD: C00096];
dolichyl phosphate [CPD: C00110]
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| Product |
GDP [CPD: C00035];
dolichyl beta-D-mannosyl phosphate [CPD: C03862]
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| Comment |
Acts only on long-chain polyprenyl phosphates and alpha-dihydropolyprenyl phosphates that are larger than C35.
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| History |
EC 2.4.1.83 created 1976, modified 1983
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| Pathway |
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| Orthology |
| K00721 | dolichol-phosphate mannosyltransferase |
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| Genes |
» show all
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| Reference |
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| Authors |
Babczinski P, Haselbeck A, Tanner W. |
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| Title |
Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and characterization of the solubilized enzyme. |
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| Journal |
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| Reference |
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| Authors |
Bretthauer RK, Wu S, Irwin WE. |
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| Title |
Enzymatic transfer of mannose from guanosine diphosphate mannose to dolichol phosphate in yeast (Hansenula holstii). A possible step in mannan synthesis. |
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| Journal |
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| Reference |
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| Authors |
Haselbeck A. |
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| Title |
Purification of GDP mannose:dolichyl-phosphate O-beta-D-mannosyltransferase from Saccharomyces cerevisiae. |
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| Journal |
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| Reference |
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| Authors |
Palamarczyk G, Lehle L, Mankowski T, Chojnacki T, Tanner W. |
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| Title |
Specificity of solubilized yeast glycosyl transferases for polyprenyl derivatives. |
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| Journal |
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| Reference |
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| Authors |
Richards JB, Hemming FW. |
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| Title |
The transfer of mannose from guanosine diphosphate mannose to dolichol phosphate and protein by pig liver endoplasmic reticulum. |
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| Journal |
Biochem J 130:77-93 (1972) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.4.1.83 |
| ExPASy - ENZYME nomenclature database: | 2.4.1.83 |
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