Entry
Name
xanthine phosphoribosyltransferase;
Xan phosphoribosyltransferase;
xanthosine 5'-phosphate pyrophosphorylase;
xanthylate pyrophosphorylase;
xanthylic pyrophosphorylase;
XMP pyrophosphorylase;
5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase;
9-(5-phospho-beta-D-ribosyl)xanthine:diphosphate 5-phospho-alpha-D-ribosyltransferase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
Reaction(IUBMB)
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine [RN:
R02142 ]
Reaction(KEGG)
Substrate
Product
5-phospho-alpha-D-ribose 1-diphosphate [CPD:
C00119 ];
xanthine [CPD:
C00385 ]
History
EC 2.4.2.22 created 1972
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K00769 xanthine phosphoribosyltransferase
K03816 xanthine phosphoribosyltransferase
Genes
ECOC : C3026_01130 C3026_23865
ECOO : ECRM13514_0249(gpt)
ECOH : ECRM13516_0247(gpt)
EDJ : ECDH1ME8569_0226(gpt)
REE : electrica_04092(gpt)
RTG : NCTC13098_05994(gpt)
CLAP : NCTC11466_03679(gpt)
KIE : NCTC12125_02784(gpt)
LEW : DAI21_00005 DAI21_00075
AHN : NCTC12129_01041(gpt)
METY : MRY16398_45440(gpt)
PSHI : SAMEA2665130_2257(gpt)
YPI : YpsIP31758_3153(gpt)
SFJ : SAMEA4384070_0994(gpt)
SOF : NCTC11214_00533(gpt)
ROX : BV494_00005 BV494_00060
PARL : PEC302110_30450(gpt)
BAPF : BUMPF009_CDS00345(gpt)
BAPG : BUMPG002_CDS00346(gpt)
BAPU : BUMPUSDA_CDS00345(gpt)
BAPW : BUMPW106_CDS00345(gpt)
TPTY : NCTC11468_02947(gpt)
PHEI : NCTC12003_00894(gpt)
LRI : NCTC12151_01102(gpt)
HIT : NTHI0796(gpt) NTHI0814(gpt2)
HIP : CGSHiEE_08725 CGSHiEE_08800
HIQ : CGSHiGG_06650 CGSHiGG_06750
HIE : R2846_1645(gptB) R2846_1660(gptA)
HIZ : R2866_1784(gptB) R2866_1800(gptA)
HIK : HifGL_000303(gpt2) HifGL_000393
HIH : NF38_01680 NF38_01760
HIW : NTHI477_01772(gpt_1) NTHI477_01789(gpt_2)
HIC : NTHIC486_00307(gpt_1) NTHIC486_00321(gpt_2)
HIX : NTHI723_01012(gpt_1) NTHI723_01028(gpt_2)
HPIT : NCTC13334_00501(gpt)
HHZ : NCTC10839_00465(gpt)
HAEG : NCTC8502_00530(gpt)
ADP : NCTC12871_00033(gpt)
ALIG : NCTC10568_01282(gpt)
ASEG : NCTC10977_00391(gpt)
RPNE : NCTC8284_00368(gpt_1)
PAET : NCTC13378_02109(gpt)
VAU : VANGNB10_cI2063c(gpt)
VEU : IXK98_20765(tet(34))
VSI : MTO69_03035(tet(34))
VNL : D3H41_03380(tet(34))
VCC : FAZ90_03520(tet(34))
VKA : BTD91_03110(tet(34))
VNV : IF132_11950(tet(34))
VGI : MID13_12145(tet(34))
VSL : LTQ54_12215(tet(34))
VPL : SA104470976_00535(gpt)
VJP : NP165_03135(tet(34))
VPG : LZI70_10245(tet(34))
VCRA : IS519_14140(tet(34))
VNP : KW548_05305(tet(34))
VLE : ISX51_04825(tet(34))
VIB : VspSTUT11_23240(gpt)
VIS : VspSTUT16_24490(gpt)
VIO : AB2S62_03215(tet(34))
PPRC : PFLCHA0_c59920(xpt)
PMUD : NCTC8068_05240(xpt)
PFW : PF1751_v1c53760(xpt)
PTAE : NCTC10697_00074(xpt)
MVS : MVIS_0571(gpt) MVIS_1124(xpt)
MMAA : FR932_12065 FR932_14740
MOQ : HWV03_16545 HWV03_19270(gpt)
RHEI : ATY27_10130 ATY27_19525
HAAH : HALA3H3_830130(gpt)
AEL : NCTC12917_00912(gpt)
PLG : NCTC10937_00181(xpt)
THAG : CKCBHOJB_01779(xpt)
SAME : SAMCFNEI73_Ch1754(gpt)
ASAL : CFBP5507_07270(gpt)
ALEG : CFBP4996_06990(gpt)
REC : RHECIAT_CH0001840(gpt)
RLW : RlegWSM1455_07915(gpt)
BCAN : BcanWSM471_24820(gpt)
MAQU : Maq22A_1p32850(apt)
MTUN : MTUNDRAET4_2029(gpt)
PPIC : PhaeoP14_01583(gpt)
SINL : DSM14862_01728(gpt)
SPSE : SULPSESMR1_01772(gpt)
RMM : ROSMUCSMR3_03840(gpt)
AHT : ANTHELSMS3_03355(gpt)
LALG : LentiSH36_01323(gpt)
LVS : LOKVESSMR4R_01258(gpt)
HCL : NCTC13205_00986(gpt)
HSH : NHP194022_07990(gpt)
HPUL : NCTC13154_01121(gpt)
SMAB : LN246_02605 LN246_13175
PPOR : JCM14722_03460(gpt)
BTHO : Btheta7330_02950(xpt)
BCEL : BcellWH2_00511(xpt)
BSTE : K6V31_01855(xpt) K6V31_02585
PCAG : NCTC12856_00065(xpt)
COPR : Cop2CBH44_06510(xpt)
CFAS : Cfast33896_00400(xpt)
PMZ : HMPREF0659_A5459(xpt)
PDN : HMPREF9137_1046(xpt)
STHA : NCTC11429_04705(xpt)
BSTR : QI003_10940(xpt) QI003_14370(xpt)
BLEN : NCTC4824_01990(xpt)
SAX : USA300HOU_0411(xprT)
SUQ : HMPREF0772_10106(xpt)
SUX : SAEMRSA15_03400(xpt)
SUF : SARLGA251_03480(xpt)
SAUT : SAI1T1_2002950(xprT)
SAUJ : SAI2T2_1002950(xprT)
SAUK : SAI3T3_1002950(xprT)
SAUQ : SAI4T8_1002950(xprT)
SAUV : SAI7S6_1002950(xpt)
SAUW : SAI5S5_1002940(xpt)
SAUX : SAI6T6_1002950(xpt)
SAUY : SAI8T7_1002950(xpt)
SDP : NCTC12225_02646(xpt)
SPIC : SAMEA4384060_2479(xprT)
SSH : NCTC13712_00332(xpt)
SSIM : SAMEA4384339_0345(xprT)
SSTE : SAMEA4384403_2457(xprT)
LMOC : LMOSLCC5850_1947(xpt)
LMW : LMOSLCC2755_1945(xpt)
LMX : LMOSLCC2372_1951(xpt)
LMZ : LMOSLCC2482_1946(xpt)
LMON : LMOSLCC2376_1846(xpt)
LMOS : LMOSLCC7179_1857(xpt)
LMOO : LMOSLCC2378_1908(xpt)
LMOY : LMOSLCC2479_1948(xpt)
LMOT : LMOSLCC2540_1966(xpt)
LMOA : LMOATCC19117_1903(xpt)
LGZ : NCTC10812_00934(xpt)
GMO : NCTC11323_01483(xpt)
GHA : NCTC10459_01518(xpt)
PJD : Pjdr2_1053 Pjdr2_2159 Pjdr2_3999
GYM : GYMC10_0727 GYMC10_4563
PPM : PPSC2_09110(xpt1) PPSC2_24725(xpt3)
PPO : PPM_1735(xpt1) PPM_4913(xpt3)
PPOL : X809_09370 X809_41280
PPQ : PPSQR21_018130 PPSQR21_050060
PPOY : RE92_03185 RE92_12560
PMS : KNP414_01661(xpt) KNP414_06868(xpt2) KNP414_07913(xpt3)
PMQ : PM3016_1968 PM3016_6480 PM3016_7430
PMW : B2K_09985 B2K_32735 B2K_37465
PTA : HPL003_06580 HPL003_17130
PSAB : PSAB_02045 PSAB_09900 PSAB_23385
PDU : PDUR_02360 PDUR_11210
PBD : PBOR_02765 PBOR_13195 PBOR_34925
PGM : PGRAT_02975 PGRAT_12110 PGRAT_31245
POD : PODO_02590 PODO_10615 PODO_29620
PAEN : P40081_03005 P40081_12925 P40081_36235
PAEF : R50345_02500 R50345_10985 R50345_29715
PAEQ : R50912_02705 R50912_12515 R50912_32840
PSTE : PSTEL_02865 PSTEL_11185 PSTEL_26110
PAEA : R70723_02335 R70723_11640 R70723_31610
PAEE : R70331_02300 R70331_11390 R70331_30360
PAEH : H70357_02605 H70357_13030 H70357_33895
PAEJ : H70737_02610 H70737_10420 H70737_29360
PBJ : VN24_00190 VN24_17040
PIH : UB51_14075 UB51_24450
PRI : PRIO_0640(xpt1) PRIO_2583(xpt3) PRIO_6530(xpt5)
PSON : JI735_07360 JI735_11625 JI735_21860
PPEO : ABE82_09205 ABE82_25025
PNP : IJ22_06780 IJ22_29880
POW : IJ21_31170 IJ21_38160
PBV : AR543_01670 AR543_05185 AR543_10535
PXL : BS614_06575 BS614_14250
PYG : AWM70_04145 AWM70_21490
PDH : B9T62_07665 B9T62_30420 B9T62_34895
PIB : BBD41_11205 BBD41_22555
PCX : LPB68_09480 LPB68_18625
PKB : B4V02_00310 B4V02_16185
PAIH : ASL14_02270 ASL14_12740
PVO : PVOR_05925 PVOR_24499
PLW : D5F53_07380 D5F53_25965
PLEN : EIM92_00775 EIM92_18925
PPSC : EHS13_18770 EHS13_22165
PLUT : EI981_03370 EI981_19195
PALB : EJC50_08230 EJC50_22755
PCHI : PC41400_04625 PC41400_10305
PBK : Back11_07150(xpt_1) Back11_35700(xpt_2)
PPRT : ET464_01970 ET464_02070 ET464_13225
PBAC : HUB98_20215 HUB98_27235
PSOP : KP014_05540 KP014_13715
PTRI : KDC22_02620 KDC22_11325 KDC22_31725
PTJ : JRJ22_09870 JRJ22_28055
PALR : HGI30_08715 HGI30_22390
PKA : PQ456_02460 PQ456_07960 PQ456_21965
PUI : PUW25_02345 PUW25_08915
PMAH : PTQ21_08105 PTQ21_15600
PMAE : LMZ02_09735 LMZ02_15925
PWN : QNH46_03705 QNH46_09720
PSPN : L1F29_21170 L1F29_23170
PPOG : QPK24_02455 QPK24_08315
PAUN : MJA45_18980 MJA45_25115
PHK : SK066_15420 SK066_21150 SK066_22185
PNK : AASFL403_10955 AASFL403_16650 AASFL403_19730
PPAB : KET34_03060 KET34_11710
PKP : SK3146_01449(xpt_1) SK3146_01917(xpt_2) SK3146_03919(xpt_3)
PGLU : A3958_00890 A3958_12815
PLZH : C0638_08565 C0638_24050
PACL : DCC85_02805 DCC85_08065
PEZZ : HW560_02450 HW560_27855
COH : EAV92_11325 EAV92_22160
COHN : KCTCHS21_20290(xpt_1) KCTCHS21_27260(xpt_2)
CCHL : FPL14_24090 FPL14_24270
CHEB : HH215_01005 HH215_01795
SACA : FFV09_13725 FFV09_18720
SPH : MGAS10270_Spy0972(xpt)
SPI : MGAS10750_Spy1007(xpt)
SPJ : MGAS2096_Spy0932(xpt)
SPK : MGAS9429_Spy0975(xpt)
STZ : SPYALAB49_000855(xpt)
SNV : SPNINV200_16670(xpt)
SNC : HMPREF0837_12070(xpt)
SPNE : SPN034156_06930(xpt)
SPNU : SPN034183_16230(xpt)
SPNM : SPN994038_16120(xpt)
SPNO : SPN994039_16130(xpt)
SGG : SGGBAA2069_c10050(xpt)
SCP : HMPREF0833_10483(xpt)
SVB : NCTC12167_01275(xpt)
SMEN : SAMEA4412692_0487(xpt)
SFER : NCTC12278_00965(xpt)
SCAI : NCTC12191_01553(xpt)
SPSU : NCTC13786_00185(xpt)
SPOC : NCTC10925_00987(xpt)
SAUP : NCTC3168_01667(xpt)
SURN : NCTC13766_01058(xpt)
SMIE : NCTC11169_00868(xpt)
LPW : LpgJCM5343_02320(xpt)
LRU : HMPREF0538_20554(xpt)
LOR : AYI71_03775 AYI71_11395
EFU : HMPREF0351_11199(xpt)
ECEC : NCTC12421_01127(xpt)
VLU : M2919_04750 M2919_05775
VIE : OL234_02970 OL234_08770
AUR : HMPREF9243_0641(xpt)
CPF : CPF_0319(xpt) CPF_1498(xpt)
CPR : CPR_0313(xpt_1) CPR_1287(xpt_2)
CBO : CBO0317(xpt) CBO1139(xpt)
CBA : CLB_0360(xpt-1) CLB_1176(xpt-2)
CBH : CLC_0375(xpt-1) CLC_1188(xpt-2)
CBY : CLM_0385(xpt) CLM_1295(xpt)
CBL : CLK_0579(xpt) CLK_3506(xpt)
CBB : CLD_0436(xpt) CLD_3424(xpt)
CBI : CLJ_B0371(xpt_1) CLJ_B1186(xpt_2)
CBF : CLI_0387(xpt-1) CLI_1225(xpt-2)
CBM : CBF_0355(xpt-1) CBF_1197(xpt-2)
CBJ : H04402_00326 H04402_01214
CLD : CLSPO_c03480(xpt1) CLSPO_c11460(xpt2)
CARG : RSJ17_05790 RSJ17_16050
CCOH : SAMEA4530647_2054(xpt)
CGEL : psyc5s11_39140(xpt1)
SARJ : HH195_02840 HH195_03920
CLO : HMPREF0868_1085(xpt)
FPLA : A4U99_00130 A4U99_12625
PFAA : MM59RIKEN_13400(xpt)
VFA : MM35RIKEN_07730(xpt)
VCOP : MM50RIKEN_14240(xpt)
ANQ : PYS63_02180 PYS63_02330
IBU : IB211_01066c IB211_03362c
BPRO : PMF13cell1_02570(xpt)
CSCI : HDCHBGLK_02374(xpt)
CHYL : CE91St63_26240(xpt)
PDF : CD630DERM_23300(xpt)
PEB : O0R46_05295 O0R46_07005
PHAR : NCTC13077_00561(xpt)
VDN : NCTC11831_00345(xpt)
PFAC : PFJ30894_00988(xpt)
AARG : Aargi30884_03180(xpt1)
ABSI : A9CBEGH2_04300(xpt1)
FIT : Fi14EGH31_15750(xpt)
BBV : HMPREF9228_0981(xpt)
GVG : HMPREF0421_21105(xpt)
GVA : HMPREF0424_0364(xpt)
GVH : HMPREF9231_0433(xpt)
» show all
Taxonomy
Reference
Authors
Krenitsky TA, Neil SM, Miller RL.
Title
Guanine and xanthine phosphoribosyltransfer activities of Lactobacillus casei and Escherichia coli. Their relationship to hypoxanthine and adenine phosphoribosyltransfer activities.
Journal
J Biol Chem 245:2605-11 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.22
ExPASy - ENZYME nomenclature database: 2.4.2.22