KEGG   ENZYME: 2.4.2.45
Entry
EC 2.4.2.45                 Enzyme                                 

Name
decaprenyl-phosphate phosphoribosyltransferase;
5-phospho-alpha-D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase;
5-phospho-alpha-D-ribose 1-pyrophosphate:decaprenyl phosphate 5-phosphoribosyltransferase;
DPPR synthase;
Rv3806
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate:diphosphate phospho-alpha-D-ribosyltransferase
Reaction(IUBMB)
trans,octacis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate = trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate [RN:R10095]
Reaction(KEGG)
R10095
Substrate
trans,octacis-decaprenyl phosphate [CPD:C02970];
5-phospho-alpha-D-ribose 1-diphosphate [CPD:C00119]
Product
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate [CPD:C20352];
diphosphate [CPD:C00013]
Comment
Requires Mg2+. Isolated from Mycobacterium tuberculosis. Has some activity with other polyprenyl phosphates.
History
EC 2.4.2.45 created 2012
Orthology
K14136  decaprenyl-phosphate phosphoribosyltransferase
Genes
SFO: Z042_01985
ERWI: GN242_05945
DKO: I596_3786
SAGA: M5M_17915
MMOB: F6R98_01170
NTG: NSCAC_0812
THIM: KFB96_03550
GAI: IMCC3135_22120
PNA: Pnap_3500
POS: DT070_03885
ATP: ATR_1838
SMUL: SMUL_2540
SUN: SUN_1522
GSK: KN400_1528(xapE)
GME: Gmet_1405
GLO: Glov_1962
GBM: Gbem_2584
GBN: GEOBRER4_16670(xapE)
PPD: Ppro_2111
DMA: DMR_44040
DALK: DSCA_01320
SFU: Sfum_0134
RIX: RO1_20840
RIM: ROI_08160
ADG: Adeg_1063
MTU: Rv3806c(ubiA)
MTC: MT3913
MRA: MRA_3846
MTUR: CFBS_4035
MTD: UDA_3806c
MTUB: MT7199_3875(ubiA)
MTUC: J113_26655
MTUE: J114_20330
MTUH: I917_26755
MTUL: TBHG_03744
MTUT: HKBT1_4018
MTUU: HKBT2_4028
MBO: BQ2027_MB3836C(ubia)
MBB: BCG_3868c
MBT: JTY_3870
MBX: BCGT_3668
MAF: MAF_38210
MMIC: RN08_4200
MCQ: BN44_120213(ubiA)
MLE: ML0095
MLB: MLBr00095
MPA: MAP_0214
MAO: MAP4_3657
MAVI: RC58_18185
MAVU: RE97_18220
MAV: MAV_0211
MIT: OCO_02170
MIA: OCU_02210
MID: MIP_00526
MYO: OEM_02260
MIR: OCQ_02150
MLP: MLM_0154
MUL: MUL_4990
MMC: Mmcs_5017
MKM: Mkms_5105
MJL: Mjls_5398
MMI: MMAR_5370
MMM: W7S_01065
MHAD: B586_03020
MSHG: MSG_04878
MSTO: MSTO_40840
MCOO: MCOO_30400
MSEO: MSEO_38090
MVA: Mvan_5647
MGI: Mflv_1162
MVQ: MYVA_5573
MHAS: MHAS_04491
MMAG: MMAD_51770
MMOR: MMOR_07760
MAIC: MAIC_02070
MALV: MALV_38610
MARZ: MARA_44280
MGAD: MGAD_40650
MHEV: MHEL_24390
MSAR: MSAR_13730
MANY: MANY_36390
MAUB: MAUB_30220
MPOF: MPOR_02610
MAB: MAB_0173
MABB: MASS_0171
MCHE: BB28_00885
MSTE: MSTE_00172
MMIN: MMIN_15600
MHIB: MHIB_34460
ASD: AS9A_0101
CGL: NCgl2781(Cgl2880)
CGB: cg3189
CGU: WA5_2781(ubiA)
CGT: cgR_2768
CGM: cgp_3189(ubiA)
CGJ: AR0_13990
CEF: CE2712
CDI: DIP2196
CDP: CD241_2085(ubiA)
CDH: CDB402_2060(ubiA)
CDT: CDHC01_2086(ubiA)
CDE: CDHC02_2080(ubiA)
CDR: CDHC03_2082(ubiA)
CDA: CDHC04_2112(ubiA)
CDZ: CD31A_2216(ubiA)
CDB: CDBH8_2172(ubiA)
CDS: CDC7B_2178(ubiA)
CDD: CDCE8392_2100(ubiA)
CDW: CDPW8_2161(ubiA)
CDV: CDVA01_2008(ubiA)
CDIP: ERS451417_02231(ubiA)
CJK: jk0132
CUR: cu0154
CUA: CU7111_0160(ubiA)
CAR: cauri_2375(ubiA)
CPL: Cp3995_2015(ubiA)
CPP: CpP54B96_1990(ubiA)
CPZ: CpPAT10_1966(ubiA)
COR: Cp267_2033(ubiA)
COD: Cp106_1916(ubiA)
COS: Cp4202_1953(ubiA)
CPSE: CPTA_00356
CPSU: CPTB_01173
CPSF: CPTC_00842
CRD: CRES_0529(ubiA)
CUL: CULC22_02194(ubiA)
CUC: CULC809_02042(ubiA)
CUN: Cul210932_2172(ubiA)
CUS: CulFRC11_2064(ubiA)
CUQ: Cul210931_2126(ubiA)
CUZ: Cul05146_2164(ubiA)
CUJ: CUL131002_2081c(ubiA)
CVA: CVAR_0243
CTER: A606_00985
COA: DR71_967
CSP: WM42_1637
CPHO: CPHO_11470
CAQU: CAQU_11910
CAMG: CAMM_11875
CMIN: NCTC10288_00191(ubiA)
CPRE: Csp1_25040
CSUR: N24_2980(ubiA)
NFA: NFA_1790
RER: RER_02140
REY: O5Y_01075
ROP: ROP_39340
REQ: REQ_01960
RHB: NY08_3908
GBR: Gbro_0207
GOR: KTR9_0204
TPR: Tpau_0164
SRT: Srot_0571
SCO: SCO4844(SC5G8.12)
SVE: SVEN_4890
SLE: sle_28300(sle_28300)
STRD: NI25_14725
SFK: KY5_4946
CFL: Cfla_2376
MPH: MLP_13390
TFU: Tfu_2460
NDA: Ndas_0269
NAL: B005_3137
MMAR: MODMU_4726
KRA: Krad_3882
SEN: SACE_0168
AMD: AMED_0226
AMN: RAM_01145
AMM: AMES_0221
AMZ: B737_0222
AOI: AORI_0229
AMYY: YIM_01195
AORI: SD37_40660
PDX: Psed_0175
PSEA: WY02_16935
PSEE: FRP1_25795
PSEH: XF36_24740
PAUT: Pdca_01300
ALO: CRK60908
CAI: Caci_5665
AFO: Afer_1739
PSER: ABRG53_2041(ubiA)
AVA: Ava_3231
ROO: G5S37_32095(ubiA)
TTF: THTE_3893
PGI: PG_0509
PGN: PGN_1463
TFO: BFO_0914
PRU: PRU_1405
CPI: Cpin_4052
MUC: MuYL_3237
FBA: FIC_00759
RAR: RIA_0061
RAG: B739_2044
RAE: G148_1548
RAT: M949_0254
EAO: BD94_1447
CHZ: CHSO_1352
CTS: Ctha_1598
 » show all
Reference
1  [PMID:15878857]
  Authors
Huang H, Scherman MS, D'Haeze W, Vereecke D, Holsters M, Crick DC, McNeil MR
  Title
Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis.
  Journal
J Biol Chem 280:24539-43 (2005)
DOI:10.1074/jbc.M504068200
  Sequence
[mtu:Rv3806c]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.45
IUBMB Enzyme Nomenclature: 2.4.2.45
ExPASy - ENZYME nomenclature database: 2.4.2.45
BRENDA, the Enzyme Database: 2.4.2.45

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