KEGG   ENZYME: 2.4.2.46
Entry
EC 2.4.2.46                 Enzyme                                 
Name
galactan 5-O-arabinofuranosyltransferase;
AftA;
Rv3792
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
galactofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 5-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 5-O-position of the eighth, tenth and twelfth galactofuranose unit of the galactofuranan chain of [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Comment
Isolated from Mycobacterium tuberculosis and Corynebacterium glutamicum. These arabinofuranosyl groups form the start of an arabinofuranan chain as part of the of the cell wall in mycobacteria.
History
EC 2.4.2.46 created 2012
Pathway
ec00572  Arabinogalactan biosynthesis - Mycobacterium
ec01100  Metabolic pathways
Orthology
K13686  galactan 5-O-arabinofuranosyltransferase
Genes
MTURv3792(aftA)
MTVRVBD_3792
MTCMT3899.1
MRAMRA_3832
MTFTBFG_13826
MTBTBMG_03839
MTKTBSG_03862
MTZTBXG_003809
MTGMRGA327_23350
MTECCDC5079_3521
MTURCFBS_4021
MTLCCDC5180_3470
MTOMTCTRI2_3871
MTDUDA_3792
MTNERDMAN_4158
MTJJ112_20385
MTUBMT7199_3861(aftA)
MTUEJ114_20250
MTXM943_19480
MTULTBHG_03730
MTUTHKBT1_4004
MTUUHKBT2_4014
MTQHKBS1_4017
MBOBQ2027_MB3821(afta)
MBBBCG_3854
MBTJTY_3856
MBMBCGMEX_3855
MBKK60_039340
MBXBCGT_3653
MAFMAF_38070
MMICRN08_4181
MCEMCAN_38121
MCQBN44_120200
MCVBN43_90304
MCXBN42_90315
MCZBN45_110154
MORYMO_003943(aftA)
MLEML0107
MLBMLBr00107
MPAMAP_0233c
MAOMAP4_3638
MAVIRC58_18085
MAVURE97_18120
MAVMAV_0230
MITOCO_02350
MIAOCU_02410
MIDMIP_00565
MYOOEM_02460
MCHIAN480_01205
MIROCQ_02350
MMALCKJ54_01100
MLPMLM_0176
MMANMMAN_44830(aftA)
MSAMycsm_06179
MULMUL_4971
MMIMMAR_5354
MMAEMMARE11_51750
MLIMULP_05632(aftA)
MPSEMPSD_54770(aftA)
MSHOMSHO_08640(aftA)
MMCMmcs_5002
MKMMkms_5090
MJLMjls_5383
MMMW7S_01155
MKNMKAN_14110
MYVG155_28565
MYEAB431_27995
MHADB586_03105
MDXBTO20_02375
MSHGMSG_04856(aftA)
MFJMFLOJ_36670(aftA)
MSTOMSTO_41070(aftA)
MSIMMSIM_26110(aftA)
MSAKMSAS_32330(aftA)
MKUI2456_27385
MLWMJO58_26755
MXEMYXE_02620(aftA)
MNVMNVI_15210(aftA)
MPAGC0J29_29540
MNMMNVM_20830(aftA)
MGORH0P51_27390
MCOOMCOO_30250(aftA)
MBAIMB901379_04792(aftA)
MSEOMSEO_37890(aftA)
MHEKJMUB5695_00222(aftA)
MGAUMGALJ_45440(aftA)
MLJMLAC_44410(aftA)
MBRDMBRA_17160(aftA)
MSHJMSHI_34020(aftA)
MMAMK3U93_24030
MSPGF6B93_21855
MOTLTS72_25875
MLMMLPF_0131(aftA)
MPAAMKK62_00515
MMEHM5I08_00570
MKYIWGMT90018_61340
MADIA7U43_04855
MWUPT015_16820
MSMMSMEG_6386
MSGMSMEI_6218(aftA)
MSBLJ00_31565
MSNLI99_31570
MSHLI98_31575
MVAMvan_5629
MGIMflv_1176
MSPMspyr1_50110
MCBMycch_4981
MNED174_00360
MYNMyAD_00345
MFTXA26_57740
MPHLMPHLCCUG_00213(aftA)
MVQMYVA_5558
MLLB1R94_27190
MRHMycrhN_1953
MTHN4412656_04394(aftA)
MHASMHAS_04504(aftA)
MDUMDUV_45960(aftA)
MCHTMCHIJ_16720(aftA)
MDRMDOR_35160(aftA)
MAUUNCTC10437_05393(aftA)
MMAGMMAD_51640(aftA)
MMORMMOR_07950(aftA)
MFXMFAL_28320(aftA)
MAICMAIC_02290(aftA)
MIJMINS_04380(aftA)
MALVMALV_38750(aftA)
MTYMTOK_18450(aftA)
MPSCMPSYJ_12490(aftA)
MARZMARA_44400(aftA)
MGADMGAD_40480(aftA)
MHEVMHEL_24720(aftA)
MSARMSAR_13490(aftA)
MANYMANY_36140(aftA)
MAUBMAUB_30010(aftA)
MPOFMPOR_02360(aftA)
MPHUMPHO_39720(aftA)
MMUCC1S78_027905
MMATMMAGJ_28500(aftA)
MBOKMBOE_08990(aftA)
MFGK6L26_02940
MSEIMSEDJ_06270(aftA)
MFLVNCTC10271_00222(aftA)
MCEEMCEL_34330(aftA)
MBRML2Z93_000099
MMONEWR22_27000
MGOAFA91_04280
MHOLK3U96_01685
MSENK3U95_27495
MPAEK0O64_28090
MRFMJO55_25895
MDFK0O62_27570
MCROMI149_27915
MGROFZ046_04530
MKRMKOR_33010(aftA)
MPAKMIU77_01105
MABMAB_0190c
MMVMYCMA_0114
MABBMASS_0188
MABLMMASJCM_0192
MCHEBB28_00980
MIZBAB75_01190
MSTEMSTE_00189
MSAOMYCSP_00865
MSALDSM43276_00167(aftA)
MJDJDM601_4101
MTER4434518_04038(aftA)
MMINMMIN_15450(aftA)
MHIBMHIB_36870(aftA)
MHERK3U94_22435
MVMMJO54_22495
CGLCgl0188(Cgl0188)
CGBcg0236
CGUWA5_0185(AftA)
CGTcgR_0267
CGSC624_01290
CGGC629_01290
CGMcgp_0236
CGJAR0_01230
CGQCGLAR1_01235
CGXSB89_01010
CEFCE0162
CDIDIP0160
CDPCD241_0159(aftA)
CDHCDB402_0127(aftA)
CDTCDHC01_0160(aftA)
CDECDHC02_0166(aftA)
CDRCDHC03_0132(aftA)
CDACDHC04_0120(aftA)
CDZCD31A_0163(aftA)
CDBCDBH8_0163(aftA)
CDSCDC7B_0119(aftA)
CDDCDCE8392_0117(aftA)
CDWCDPW8_0122(aftA)
CDVCDVA01_0116(aftA)
CDIPERS451417_00127(aftA)
CJKjk0086
CURcu0105
CUACU7111_0112(aftA)
CARcauri_0101(aftA)
CKPckrop_0083
CPUCPFRC_00515
CPLCp3995_0104(aftA)
CPGCP316_00570
CPPCpP54B96_0107(aftA)
CPKCP1002_00515
CPQCPC231_00515
CPXCPI19_00515
CPZCpPAT10_0100(aftA)
CORCp267_0111(aftA)
COPCP31_00565
CODCp106_0103(aftA)
COSCp4202_0100(aftA)
COICPCIP5297_00570
COECP258_00570
COUCP162_00600
CPSECPTA_00629
CPSUCPTB_00904
CPSFCPTC_00566
CRDCRES_0492(aftA)
CULCULC22_00147(aftA)
CUCCULC809_00149(aftA)
CUECULC0102_0145(aftA)
CUNCul210932_0150(aftA)
CUQCul210931_0144(aftA)
CUZCul05146_0150(aftA)
CUJCUL131002_0134c(aftA)
CUSCulFRC11_0145(aftA)
CVACVAR_2886(aftA)
CHNA605_01275
CCNH924_00880
CTERA606_00780
CMDB841_01080
CAZCARG_00305
CFNCFAL_00610 CFAL_02180
CCGCCASEI_01370
CVTB843_00725 B843_02240
CGYCGLY_15490
CAXCATYP_00415
CIICIMIT_00500
CUVCUREI_00385
COADR71_1172(aftA)
CDOCDOO_01140
CHMB842_00690
CSXCSING_00465(aftA)
CMQB840_00765(aftA)
CKUUL82_00345(aftA)
CCJUL81_00540(aftA)
CMVCMUST_00570(aftA)
CEICEPID_00975(aftA)
CTEDCTEST_00720(aftA)
CUTCUTER_00430
CLWCLAC_00500
CDXCDES_01085(aftA)
CSPWM42_1263
CSTACSTAT_01035
CCJZccrud_01005
CFKCFRA_00775
CPHOCPHO_00630
CFCCFLV_00890
CGVCGLAU_00435(aftA)
CSTRCBE89_00375
CAQUCAQU_00415
CSPHCSPHI_00370
CAMGCAMM_01040
CMINNCTC10288_02447(aftA)
CPEGCPELA_00620(aftA)
CXEFOB82_05985
CEECENDO_00725(aftA)
CSANE3227_03615
CGKCGERO_00615(aftA)
CRFFRC0190_00165
CRLNCTC7448_00915(aftA)
CCHOCCHOA_11390(aftA)
CPRECsp1_25770(aftA)
CPSOCPPEL_00590(aftA)
CSURN24_0304(aftA)
CCYSSAMEA4530656_2419(aftA)
CMATHBA49_07750
CYZC3B44_00540
CKFI6I12_00420
CANSGP473_00420
CLIAC3E79_00515
CPRPI6I69_06360
CAMCI6I65_08005
CGLUI6J20_08735
CUOCUROG_00770(aftA)
CLIZG7Y31_00495
CSILCBE74_00685
CTUBI6I74_05840
CLUJIAU68_00410
CQNG7Y29_00425
CKWCKALI_00885(aftA)
CCOECETAM_01070(aftA)
COKCOCCU_01115(aftA)
CZOIAU67_00605
CORYFQV43_00380
CMFGWO64_000640
CWKIA203_01085
CUWLH390_00520
CPOYGP475_00870
CACCCACC_00595(aftA)
CFYI6L56_08880
CPSLKBP54_00550
CHINJ5O04_00685
CJHCJEDD_00435(aftA)
CPSPL9H27_00570
CMASCMASS_00510(aftA)
CHEICHEID_00475(aftA)
CIHUCIHUM_00385(aftA)
CCOYCCOY_00445(aftA)
CHADCHAD_00425(aftA)
CFGCFREI_00360(aftA)
CAQMCAQUA_00565(aftA)
CCAWCCANI_00355(aftA)
CAUICAURIS_00600(aftA)
CFACCFAEC_00735(aftA)
CFOUCFOUR_00395(aftA)
CFEUCFELI_00575(aftA)
CAUSCAURIC_00780(aftA)
CATRCATRI_00725(aftA)
CDURCDUR_00520(aftA)
CHANCHAN_00585(aftA)
CAFECAFEL_00415(aftA)
CGFCGUA_00710(aftA)
CGOICGOTT_00450(aftA)
CAPPCAPP_00375(aftA)
CBOVCBOVI_10025(aftA)
CSUEQP029_04645 QP029_12700
CBREQP027_00205
CPYRCYJ47_11635
BFVC628_01125
NFANFA_1950(aftA)
NFRERS450000_04043(aftA)
NCYNOCYR_0153
NBRO3I_000795
NNONONO_c01570
NSLBOX37_00860
NSRNS506_00804(aftA)
NTPCRH09_00865
NOZDMB37_21815
NODFOH10_30715
NAHF5544_00905
NADNCTC11293_00939(aftA)
NWLNWFMUON74_01360
NIEKV110_00780
NTCKHQ06_33440
NHUH0264_02030
NYALTV02_30730
NGPLTT66_13630
NSPUIFM12276_65800(aftA)
RHARHA1_ro04076
RERRER_02330(aftA)
REYO5Y_01175
REBXU06_01190
RQIC1M55_01195
ROPROP_39510(aftA)
ROAPd630_LPD00474
RPYY013_17535
RBYCEJ39_03940
RHBNY08_3924
RAVAAT18_01570
RFAA3L23_02040(aftA)
RHSA3Q41_01323(aftA)
RHWBFN03_17040
RRZCS378_17750
RHUA3Q40_03631(aftA)
RHQIM25_07470
RHODAOT96_11750
RRT4535765_00237(aftA)
RCRNCTC10994_02454(aftA)
RTMG4H71_09070
RKOJWS14_22270
RGOKYT97_20765
ROZCBI38_02290
RPSKJWS13_22675
RGORNMQ04_00905
RHOPD8W71_02490
REQREQ_02200
PDEFP9209_02100
WHROG579_11250
GBRGbro_0250
GPOGPOL_c04350(aftA)
GORKTR9_0241
GOQACH46_01260
GTABCM27_01665
GOCCXX93_02025
GITC6V83_02240
GRUGCWB2_01060(aftA)
GOMD7316_03429(aftA)
GAVC5O27_03565
GODGKZ92_01370
GAMGII34_22485
GPDGII33_21995
GJIH1R19_01135
GOILK459_07725
GHNMVF96_01690
GAMIIHQ52_03160
GMGNWF22_11115
GSIP5P27_00015
SPINKV203_00975
TPRTpau_4121
TSMASU32_23390
TPULTPB0596_44980(aftA)
TSDMTP03_46360(aftA)
SRTSrot_2818
DTMBJL86_0248 BJL86_0598
DITC3V38_07700 C3V38_08815
DIZCT688_01490 CT688_02680
DPCA6048_01525 A6048_02615
DLUA6035_01875 A6035_02950
DKNNHB83_01420 NHB83_02505
TOYFO059_02210 FO059_17760
NPIG7071_18190
MMARMODMU_4713
SENSACE_5810
SACGFDZ84_04095
AMQAMETH_0241
AACDLWP59_00850 LWP59_36045
ATHML1857_03620
PSEAWY02_17060
PSEEFRP1_25680
PSEQAD006_04860
PECQAD017_12680
PHHAFB00_10420
PAUTPdca_01660
KPHYAOZ06_00955
SACEGIY23_16290
PLABC6361_25620
PLATC6W10_13230
PSUUPsuf_014910(aftA)
PRYPrubr_20140
NHYJQS43_22510
AEYCDG81_07945
 » show all
Reference
1  [PMID:16595677]
  Authors
Alderwick LJ, Seidel M, Sahm H, Besra GS, Eggeling L
  Title
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis.
  Journal
J Biol Chem 281:15653-61 (2006)
DOI:10.1074/jbc.M600045200
  Sequence
[cgl:Cgl0188] [mtu:Rv3792]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.46
IUBMB Enzyme Nomenclature: 2.4.2.46
ExPASy - ENZYME nomenclature database: 2.4.2.46
BRENDA, the Enzyme Database: 2.4.2.46

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